1HS2
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![BU of 1hs2 by Molmil](/molmil-images/mine/1hs2) | |
6VA3
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![BU of 6va3 by Molmil](/molmil-images/mine/6va3) | Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MQC | Descriptor: | 4-[(3-methoxyphenyl)amino]-2-methylquinoline-6-carboximidamide, RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | Authors: | Chen, J.L, Fountain, M.A, Disney, M.D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J.Am.Chem.Soc., 142, 2020
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6VA2
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![BU of 6va2 by Molmil](/molmil-images/mine/6va2) | Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MH5 | Descriptor: | (2E,2'E)-2,2'-{dibenzo[b,d]thiene-2,8-diyldi[(1E)eth-1-yl-1-ylidene]}bis(N-methylhydrazine-1-carboximidamide), RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | Authors: | Chen, J.L, Fountain, M.A, Disney, M.D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J.Am.Chem.Soc., 142, 2020
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6VA1
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![BU of 6va1 by Molmil](/molmil-images/mine/6va1) | Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element | Descriptor: | RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | Authors: | Chen, J.L, Fountain, M.A, Disney, M.D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J.Am.Chem.Soc., 142, 2020
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6VA4
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![BU of 6va4 by Molmil](/molmil-images/mine/6va4) | Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MIP | Descriptor: | N-[3-(8-methoxy-4-oxo-4,5-dihydro-3H-pyrimido[5,4-b]indol-3-yl)propyl]-N-methylcyclohexanaminium, RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | Authors: | Chen, J.L, Fountain, M.A, Disney, M.D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J.Am.Chem.Soc., 142, 2020
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5VH7
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![BU of 5vh7 by Molmil](/molmil-images/mine/5vh7) | Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1 | Descriptor: | RNA (5'-R(*GP*AP*CP*CP*AP*GP*CP*AP*G)-3') | Authors: | Chen, J.L, VanEtten, D.M, Fountain, M.A, Yildirim, I, Disney, M.D. | Deposit date: | 2017-04-12 | Release date: | 2017-06-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1. Biochemistry, 56, 2017
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5VH8
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![BU of 5vh8 by Molmil](/molmil-images/mine/5vh8) | Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1 | Descriptor: | RNA (5'-R(*GP*AP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*C)-3') | Authors: | Chen, J.L, VanEtten, D.M, Fountain, M.A, Yildirim, I, Disney, M.D. | Deposit date: | 2017-04-12 | Release date: | 2017-06-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1. Biochemistry, 56, 2017
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2LOA
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![BU of 2loa by Molmil](/molmil-images/mine/2loa) | Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA | Descriptor: | 4-(1,4,7,10-tetraazacyclododecan-1-ylmethyl)quinoline, DNA (5'-D(*GP*CP*CP*GP*CP*AP*GP*TP*GP*C)-3'), ZINC ION | Authors: | Morrow, J.R, Fountain, M.A, del Mundo, I.A, Siter, K.E. | Deposit date: | 2012-01-20 | Release date: | 2012-03-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA. Inorg.Chem., 51, 2012
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2LO8
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2LO5
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![BU of 2lo5 by Molmil](/molmil-images/mine/2lo5) | Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA, Structure of a Thymine bulge | Descriptor: | DNA (5'-D(*GP*GP*CP*CP*GP*CP*AP*GP*TP*GP*CP*C)-3') | Authors: | Morrow, J.R, Fountain, M.A, del Mundo, I.A, Siter, K.E. | Deposit date: | 2012-01-17 | Release date: | 2012-03-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA. Inorg.Chem., 51, 2012
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2L8U
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![BU of 2l8u by Molmil](/molmil-images/mine/2l8u) | |
2L8C
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![BU of 2l8c by Molmil](/molmil-images/mine/2l8c) | |