2LOA

Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA

Summary for 2LOA

• Entry DOI: 10.2210/pdb2loa/pdb
• Related: 2lo5 2lo8
• NMR Information: BMRB: 18199
• Descriptor: DNA (5'-D(*GP*CP*CP*GP*CP*AP*GP*TP*GP*C)-3'), 4-(1,4,7,10-tetraazacyclododecan-1-ylmethyl)quinoline, ZINC ION (3 entities in total)
• Functional Keywords: thymine bulge, bifunctional zn(ii) macrocyclic complex, dna, cyclen
• Total number of polymer chains: 1
• Total formula weight: 3424.84

Authors

Morrow, J.R.,Fountain, M.A.,del Mundo, I.A.,Siter, K.E. (deposition date: 2012-01-20, release date: 2012-03-14, Last modification date: 2023-06-14)

• Primary citation: Del Mundo, I.M.,Siters, K.E.,Fountain, M.A.,Morrow, J.R.; Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA.; Inorg.Chem., 51:5444-5457, 2012; PubMed: 22507054; DOI: 10.1021/ic3004245

Experimental method

SOLUTION NMR