5VH8

Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1

Summary for 5VH8

• Entry DOI: 10.2210/pdb5vh8/pdb
• Related: 5VH7
• NMR Information: BMRB: 30283
• Descriptor: RNA (5'-R(*GP*AP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*C)-3') (1 entity in total)
• Functional Keywords: cug repeat, triplet repeat, myotonic dystrophy, repeat expansion, uu pair, rna
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 9521.70

Authors

Chen, J.L.,VanEtten, D.M.,Fountain, M.A.,Yildirim, I.,Disney, M.D. (deposition date: 2017-04-12, release date: 2017-06-28, Last modification date: 2019-12-18)

• Primary citation: Chen, J.L.,VanEtten, D.M.,Fountain, M.A.,Yildirim, I.,Disney, M.D.; Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1.; Biochemistry, 56:3463-3474, 2017; PubMed: 28617590; DOI: 10.1021/acs.biochem.7b00252

Experimental method

SOLUTION NMR