1TC1
 
 | | A 1.4 ANGSTROM CRYSTAL STRUCTURE FOR THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE OF TRYPANOSOMA CRUZI | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FORMYCIN B, PROTEIN (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE) | | 著者 | Focia, P.J, Craig III, S.P, Nieves-Alicea, R, Fletterick, R.J, Eakin, A.E. | | 登録日 | 1998-09-30 | | 公開日 | 1999-10-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi.
Biochemistry, 37, 1998
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1TC2
 | | TERNARY SUBSTRATE COMPLEX OF THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE FROM TRYPANOSOMA CRUZI | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, MAGNESIUM ION, ... | | 著者 | Focia, P.J, Craig III, S.P, Eakin, A.E. | | 登録日 | 1998-11-04 | | 公開日 | 2000-03-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Approaching the transition state in the crystal structure of a phosphoribosyltransferase.
Biochemistry, 37, 1998
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2CNW
 | | GDPALF4 complex of the SRP GTPases Ffh and FtsY | | 分子名称: | CELL DIVISION PROTEIN FTSY, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ... | | 著者 | Focia, P.J, Gawronski-Salerno, J, Coon V, J.S, Freymann, D.M. | | 登録日 | 2006-05-24 | | 公開日 | 2006-10-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structure of a Gdp:Alf(4) Complex of the Srp Gtpases Ffh and Ftsy, and Identification of a Peripheral Nucleotide Interaction Site.
J.Mol.Biol., 360, 2006
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1OKK
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2IYL
 | | Structure of an FtsY:GDP complex | | 分子名称: | CELL DIVISION PROTEIN FTSY, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | | 著者 | Focia, P.J, Freymann, D.M. | | 登録日 | 2006-07-18 | | 公開日 | 2007-01-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray structure of the T. aquaticus FtsY:GDP complex suggests functional roles for the C-terminal helix of the SRP GTPases.
Proteins, 66, 2007
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4UUJ
 | | POTASSIUM CHANNEL KCSA-FAB WITH TETRAHEXYLAMMONIUM | | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | | 著者 | Lenaeus, M.J, Burdette, D, Wagner, T, Focia, P.J, Gross, A. | | 登録日 | 2014-07-29 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
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6D71
 | | Crystal Structure of the Human Miro1 N-terminal GTPase bound to GTP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 1 | | 著者 | Smith, K.P, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2018-04-23 | | 公開日 | 2019-10-09 | | 最終更新日 | 2022-10-05 | | 実験手法 | X-RAY DIFFRACTION (1.7180779 Å) | | 主引用文献 | Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase.
J.Struct.Biol., 212, 2020
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3IFX
 | | Crystal structure of the Spin-labeled KcsA mutant V48R1 | | 分子名称: | POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, TETRABUTYLAMMONIUM ION, ... | | 著者 | Cieslak, J.A, Focia, P.J, Gross, A. | | 登録日 | 2009-07-26 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | EPR (3.56 Å), X-RAY DIFFRACTION | | 主引用文献 | Electron Spin-Echo Envelope Modulation (ESEEM) Reveals Water and Phosphate Interactions with the KcsA Potassium Channel
Biochemistry, 49, 2010
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2O26
 | | Structure of a class III RTK signaling assembly | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor, ... | | 著者 | Liu, H, Chen, X, Focia, P.J, He, X. | | 登録日 | 2006-11-29 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.
Embo J., 26, 2007
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3EJJ
 | | Structure of M-CSF bound to the first three domains of FMS | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Colony stimulating factor-1, Macrophage colony-stimulating factor 1 receptor | | 著者 | Chen, X, Liu, H, Focia, P.J, Shim, A, He, X. | | 登録日 | 2008-09-18 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.
Proc.Natl.Acad.Sci.USA, 105, 2008
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2W0F
 | | Potassium Channel KcsA-Fab Complex with Tetraoctylammonium | | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | | 著者 | Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A. | | 登録日 | 2008-08-14 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
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2BOC
 | | Potassium channel KcsA-Fab complex in thallium with tetraethylarsonium (TEAs) | | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | | 著者 | Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A. | | 登録日 | 2005-04-09 | | 公開日 | 2005-04-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
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2BOB
 | | Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA) | | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | | 著者 | Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A. | | 登録日 | 2005-04-09 | | 公開日 | 2005-04-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
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2JK5
 | | Potassium Channel KcsA in complex with Tetrabutylammonium in high K | | 分子名称: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ... | | 著者 | Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A. | | 登録日 | 2008-08-15 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
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5KUT
 | | hMiro2 C-terminal GTPase domain, GDP-bound | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 2 | | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2016-07-13 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.693 Å) | | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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5KSY
 | | hMiro1 C-domain GDP Complex P41212 Crystal Form | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mitochondrial Rho GTPase 1 | | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2016-07-10 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.482 Å) | | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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5KSZ
 | | hMiro EF hand and cGTPase domains in the GMPPCP-bound state | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Mitochondrial Rho GTPase 1, ... | | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2016-07-10 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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5KTY
 | | hMiro EF hand and cGTPase domains, GDP and Ca2+ bound state | | 分子名称: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2016-07-12 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.522 Å) | | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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5KSP
 | | hMiro1 C-domain GDP Complex C2221 Crystal Form | | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Mitochondrial Rho GTPase 1 | | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2016-07-08 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.162 Å) | | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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1I0I
 | | ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-GLUTAMINE MUTANT | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ... | | 著者 | Canyuk, B, Focia, P.J, Eakin, A.E. | | 登録日 | 2001-01-29 | | 公開日 | 2002-05-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
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1I0L
 | | ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ASPARAGINE MUTANT | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ... | | 著者 | Canyuk, B, Focia, P.J, Eakin, A.E. | | 登録日 | 2001-01-29 | | 公開日 | 2002-05-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
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1I13
 | | ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ALANINE MUTANT | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, FORMIC ACID, ... | | 著者 | Canyuk, B, Focia, P.J, Eakin, A.E. | | 登録日 | 2001-01-30 | | 公開日 | 2002-05-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
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1I14
 | | ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-GLUTAMIC ACID MUTANT | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ... | | 著者 | Canyuk, B, Focia, P.J, Eakin, A.E. | | 登録日 | 2001-01-30 | | 公開日 | 2002-05-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
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5KSO
 | | hMiro1 C-domain GDP-Pi Complex P3121 Crystal Form | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mitochondrial Rho GTPase 1, PHOSPHATE ION | | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2016-07-08 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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5KU1
 | | hMiro1 EF hand and cGTPase domains in the GDP-bound state | | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2016-07-12 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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