6C2T
| Aurora A ligand complex | Descriptor: | (2S,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid, Aurora kinase A, DIMETHYL SULFOXIDE, ... | Authors: | Antonysamy, S, Pustilnik, A, Manglicmot, D, Froning, K, Weichert, K, Wasserman, S. | Deposit date: | 2018-01-08 | Release date: | 2019-01-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene. Cancer Discov, 9, 2019
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7W91
| Residues 440-490 of centrosomal protein 63 | Descriptor: | Centrosomal protein of 63 kDa | Authors: | Yun, H.Y, Ku, B. | Deposit date: | 2021-12-09 | Release date: | 2023-07-19 | Method: | X-RAY DIFFRACTION (3.292 Å) | Cite: | Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells. Commun Biol, 6, 2023
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8JT6
| 5-HT1A-Gi in complex with compound (R)-IHCH-7179 | Descriptor: | 1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Chen, Z, Xu, P, Huang, S, Xu, H.E, Wang, S. | Deposit date: | 2023-06-21 | Release date: | 2024-02-28 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Flexible scaffold-based cheminformatics approach for polypharmacological drug design. Cell, 187, 2024
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6DR3
| Crystal structure of E. coli LpoA amino terminal domain | Descriptor: | Penicillin-binding protein activator LpoA | Authors: | Kelley, A.C, Saper, M.A. | Deposit date: | 2018-06-11 | Release date: | 2019-05-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Crystal structures of the amino-terminal domain of LpoA from Escherichia coli and Haemophilus influenzae. Acta Crystallogr.,Sect.F, 75, 2019
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6DCJ
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3CKM
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7UHE
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