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4K7Z
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BU of 4k7z by Molmil
Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADP and Hg2+
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MERCURY (II) ION, ...
Authors:Dong, A, Falkowaski, M, Malone, M, Miller, S.M, Pai, E.F.
Deposit date:2013-04-17
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADP and Hg2+
To be Published
4K8D
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BU of 4k8d by Molmil
Crystal structure of the C558(464)A/C559(465)A double mutant of Tn501 MerA in complex with NADPH and Hg2+
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Mercuric reductase, ...
Authors:Dong, A, Falkowski, M, Malone, M, Miller, S.M, Pai, E.F.
Deposit date:2013-04-18
Release date:2013-05-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADPH and Hg2+
to be published
1ZK7
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BU of 1zk7 by Molmil
Crystal Structure of Tn501 MerA
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Mercuric reductase, ...
Authors:Dong, A, Ledwidge, R, Patel, B, Fiedler, D, Falkowski, M, Zelikova, J, Summers, A.O, Pai, E.F, Miller, S.M.
Deposit date:2005-05-02
Release date:2005-07-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:NmerA, the Metal Binding Domain of Mercuric Ion Reductase, Removes Hg(2+) from Proteins, Delivers It to the Catalytic Core, and Protects Cells under Glutathione-Depleted Conditions
Biochemistry, 44, 2005
1ZX9
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BU of 1zx9 by Molmil
Crystal Structure of Tn501 MerA
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Mercuric reductase
Authors:Dong, A, Ledwidge, R, Patel, B, Fiedler, D, Falkowski, M, Zelikova, J, Summers, A.O, Pai, E.F, Miller, S.M.
Deposit date:2005-06-07
Release date:2005-07-05
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:NmerA, the Metal Binding Domain of Mercuric Ion Reductase, Removes Hg(2+) from Proteins, Delivers It to the Catalytic Core, and Protects Cells under Glutathione-Depleted Conditions
Biochemistry, 44, 2005
7A8P
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BU of 7a8p by Molmil
Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.
Descriptor: (3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid, DNA-directed RNA polymerase, mitochondrial
Authors:Hillen, H.S, Bonekamp, N, Peter, B, Felser, A, Bergbrede, T, Choidas, A, Horn, M, Unger, A, di Lucrezia, R, Atanassov, I, Li, X, Koch, U, Menninger, S, Boros, J, Habenberger, P, Giavalisco, P, Cramer, P, Denzel, M, Nussbaumer, P, Klebl, B, Falkenberg, M, Gustafsson, C.M, Larsson, N.G.
Deposit date:2020-08-30
Release date:2020-12-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Small-molecule inhibitors of human mitochondrial DNA transcription.
Nature, 588, 2020
4TV3
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BU of 4tv3 by Molmil
Isolated p110a subunit of PI3Ka provides a platform for structure-based drug design
Descriptor: 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Chen, P, Deng, Y.-L, Bergqvist, S, Falk, M, Liu, W, Timofeevski, S.
Deposit date:2014-06-25
Release date:2014-08-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Engineering of an isolated p110 alpha subunit of PI3K alpha permits crystallization and provides a platform for structure-based drug design.
Protein Sci., 23, 2014
4TUU
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BU of 4tuu by Molmil
Isolated p110a subunit of PI3Ka provides a platform for structure-based drug design
Descriptor: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Chen, P, Deng, Y.-L, Bergqvist, S, Falk, M, Liu, W, Timofeevski, S.
Deposit date:2014-06-24
Release date:2014-08-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Engineering of an isolated p110 alpha subunit of PI3K alpha permits crystallization and provides a platform for structure-based drug design.
Protein Sci., 23, 2014
6RCL
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BU of 6rcl by Molmil
Crystal structure of REXO2-D199A-AA
Descriptor: MAGNESIUM ION, Oligoribonuclease, mitochondrial, ...
Authors:Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M.
Deposit date:2019-04-11
Release date:2019-10-09
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Mol.Cell, 76, 2019
7P0M
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BU of 7p0m by Molmil
Human mitochondrial Lon protease with substrate in the ATPase and protease domains
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-30
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P0B
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BU of 7p0b by Molmil
Human mitochondrial Lon protease without substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-29
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P09
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BU of 7p09 by Molmil
Human mitochondrial Lon protease with substrate in the ATPase domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-29
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
6RCI
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BU of 6rci by Molmil
Crystal structure of REXO2
Descriptor: Oligoribonuclease, mitochondrial
Authors:Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M.
Deposit date:2019-04-11
Release date:2019-10-09
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Mol.Cell, 76, 2019
6RCN
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BU of 6rcn by Molmil
Crystal structure of REXO2-D199A-dAdA
Descriptor: DNA (5'-D(P*AP*A)-3'), MAGNESIUM ION, Oligoribonuclease, ...
Authors:Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M.
Deposit date:2019-04-11
Release date:2019-10-09
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Mol.Cell, 76, 2019
7ZC4
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BU of 7zc4 by Molmil
Cryo-EM structure of POLRMT mutant.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2022-03-25
Release date:2023-02-01
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
2KT2
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BU of 2kt2 by Molmil
Structure of NmerA, the N-terminal HMA domain of Tn501 Mercuric Reductase
Descriptor: Mercuric reductase
Authors:Ledwidge, R, Danacea, F, Dotsch, V, Miller, S.M.
Deposit date:2010-01-17
Release date:2010-09-22
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:NmerA of Tn501 mercuric ion reductase: structural modulation of the pKa values of the metal binding cysteine thiols.
Biochemistry, 49, 2010
2KT3
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BU of 2kt3 by Molmil
Structure of Hg-NmerA, Hg(II) complex of the N-terminal domain of Tn501 Mercuric Reductase
Descriptor: MERCURY (II) ION, Mercuric reductase
Authors:Miller, S.M, Ledwidge, R, Danacea, F, Dotsch, V.
Deposit date:2010-01-17
Release date:2010-09-22
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:NmerA of Tn501 mercuric ion reductase: structural modulation of the pKa values of the metal binding cysteine thiols.
Biochemistry, 49, 2010
7PZR
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BU of 7pzr by Molmil
Cryo-EM structure of POLRMT in free form.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-10-13
Release date:2022-11-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
7PZP
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BU of 7pzp by Molmil
Mitochondrial DNA dependent RNA polymerase homodimer.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-10-13
Release date:2022-09-28
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022

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PDB entries from 2024-11-20

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