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1ITG
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BU of 1itg by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES
分子名称: CACODYLATE ION, HIV-1 INTEGRASE
著者Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R.
登録日1994-11-21
公開日1995-05-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.
Science, 266, 1994
1PYD
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BU of 1pyd by Molmil
CATALYTIC CENTERS IN THE THIAMIN DIPHOSPHATE DEPENDENT ENZYME PYRUVATE DECARBOXYLASE AT 2.4 ANGSTROMS RESOLUTION
分子名称: MAGNESIUM ION, PYRUVATE DECARBOXYLASE, THIAMINE DIPHOSPHATE
著者Furey, W, Dyda, F.
登録日1993-03-23
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4-A resolution.
Biochemistry, 32, 1993
9AZ7
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BU of 9az7 by Molmil
Chloride Sites in Photoactive Yellow Protein
分子名称: 4'-HYDROXYCINNAMIC ACID, CHLORIDE ION, Photoactive yellow protein
著者Dyda, F, Schotte, F, Anfinrud, P, Cho, H.S.
登録日2024-03-10
公開日2024-03-20
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein.
Struct Dyn., 11, 2024
9AZ9
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BU of 9az9 by Molmil
Chloride Sites in Photoactive Yellow Protein (Chloride-Free Reference Structure)
分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
著者Dyda, F, Schotte, F, Anfinrud, P, Cho, H.S.
登録日2024-03-10
公開日2024-03-20
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein.
Struct Dyn., 11, 2024
6B67
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BU of 6b67 by Molmil
Human PP2Calpha (PPM1A) complexed with cyclic peptide c(MpSIpYVA)
分子名称: CALCIUM ION, Protein phosphatase 1A, cyclic peptide c(MpSIpYVA)
著者Dyda, F, Kosek, D.
登録日2017-10-01
公開日2018-04-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.
J. Biol. Chem., 293, 2018
6OPM
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BU of 6opm by Molmil
Casposase bound to integration product
分子名称: CALCIUM ION, CRISPR-associated endonuclease Cas1, DNA 21-mer, ...
著者Dyda, F, Hickman, A.B, Kailasan, S.
登録日2019-04-25
公開日2020-02-12
最終更新日2020-08-26
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas.
Elife, 9, 2020
1UUT
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BU of 1uut by Molmil
The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat
分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*TP*TP*GP *AP*GP*CP*TP*G)-3', CHLORIDE ION, MAGNESIUM ION, ...
著者Dyda, F, Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M.
登録日2004-01-10
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces
Mol.Cell, 13, 2004
6DWZ
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BU of 6dwz by Molmil
Hermes transposase deletion dimer complex with (C/G) DNA
分子名称: DNA (26-MER), DNA (5'-D(*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*C)-3'), ...
著者Dyda, F, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DX0
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BU of 6dx0 by Molmil
Hermes transposase deletion dimer complex with (A/T) DNA
分子名称: DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ...
著者Dyda, F, Voth, A.R, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DWW
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BU of 6dww by Molmil
Hermes transposase deletion dimer complex with (A/T) DNA and Mn2+
分子名称: DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ...
著者Dyda, F, Voth, A.R, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.851 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DWY
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BU of 6dwy by Molmil
Hermes transposase deletion dimer complex with (C/G) DNA and Ca2+
分子名称: CALCIUM ION, DNA (26-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), ...
著者Dyda, F, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
7TH0
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BU of 7th0 by Molmil
Escherichia coli RpnA-S
分子名称: Recombination-promoting nuclease RpnA
著者Zhong, A, Hickman, A.B, Storz, G, Dyda, F.
登録日2022-01-10
公開日2023-03-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SJD
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BU of 8sjd by Molmil
Cryo-EM structure of the Hermes transposase bound to two right-ends of its DNA transposon.
分子名称: DNA (46-MER), DNA (55-MER), DNA (8-MER), ...
著者Lannes, L, Dyda, F.
登録日2023-04-17
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
1BIS
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BU of 1bis by Molmil
HIV-1 INTEGRASE CORE DOMAIN
分子名称: HIV-1 INTEGRASE
著者Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R.
登録日1998-06-19
公開日1998-08-19
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BIU
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BU of 1biu by Molmil
HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++
分子名称: HIV-1 INTEGRASE, MAGNESIUM ION
著者Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R.
登録日1998-06-19
公開日1998-08-19
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BIZ
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BU of 1biz by Molmil
HIV-1 INTEGRASE CORE DOMAIN
分子名称: CACODYLATE ION, HIV-1 INTEGRASE
著者Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R.
登録日1998-06-21
公開日1998-08-19
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
8EB5
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BU of 8eb5 by Molmil
Tandem of Hermes transposase BED domain in complex with the quasi palindrome of its transposon left-end
分子名称: Hermes transposase BED domain, Hermes transposon left-end subterminal repeats 1 and 2, ZINC ION
著者Lannes, L, Dyda, F.
登録日2022-08-30
公開日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
8EDG
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BU of 8edg by Molmil
Cryo-EM structure of the Hermes transposase bound to two left-ends of its DNA transposon
分子名称: DNA (46-MER), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), DNA (55-MER), ...
著者Lannes, L, Dyda, F.
登録日2022-09-04
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (4.64 Å)
主引用文献Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
1AER
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BU of 1aer by Molmil
DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH BETA-TAD
分子名称: 2-(1,5-DIDEOXYRIBOSE)-4-AMIDO-THIAZOLE, ADENOSINE MONOPHOSPHATE, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ...
著者Li, M, Dyda, F, Benhar, I, Pastan, I, Davies, D.R.
登録日1995-12-11
公開日1996-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation
Proc.Natl.Acad.Sci.USA, 93, 1996
6XGX
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BU of 6xgx by Molmil
ISCth4 transposase, strand transfer complex 1, STC1
分子名称: DNA (21-MER), DNA (25-MER), DNA (47-MER), ...
著者Kosek, D, Dyda, F.
登録日2020-06-18
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
7MGV
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BU of 7mgv by Molmil
Chryseobacterium gregarium RiPP-associated ATP-grasp ligase in complex with ADP, and a leader and core peptide
分子名称: ADENOSINE-5'-DIPHOSPHATE, CdnA3 Core peptide, CdnA3 Leader peptide, ...
著者Bewley, C.A, Zhao, G, Kosek, D, Dyda, F.
登録日2021-04-13
公開日2021-06-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural Basis for a Dual Function ATP Grasp Ligase That Installs Single and Bicyclic omega-Ester Macrocycles in a New Multicore RiPP Natural Product.
J.Am.Chem.Soc., 143, 2021
5LME
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BU of 5lme by Molmil
Specific-DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase
分子名称: ZINC ION, piggyBac transposase
著者Morellet, N, Taylor, J.A, Wieninger, S, Moriau, S, Li, X, Lescop, E, Mathy, N, Bischerour, J, Betermier, M, Bardiaux, B, Nilges, M, Craig, N.L, Hickman, A.B, Dyda, F, Guittet, E.
登録日2016-07-30
公開日2017-12-20
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase.
Nucleic Acids Res., 46, 2018
4ER8
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BU of 4er8 by Molmil
Structure of the REP associates tyrosine transposase bound to a REP hairpin
分子名称: DNA (32-MER), NICKEL (II) ION, TnpArep for protein
著者Messing, S.A.J, Ton-Hoang, B, Hickman, A.B, Ghirlando, R, Chandler, M, Dyda, F.
登録日2012-04-19
公開日2012-08-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The processing of repetitive extragenic palindromes: the structure of a repetitive extragenic palindrome bound to its associated nuclease.
Nucleic Acids Res., 40, 2012
2VJV
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BU of 2vjv by Molmil
Crystal structure of the IS608 transposase in complex with left end 26-mer DNA hairpin and a 6-mer DNA representing the left end cleavage site
分子名称: 5'-D(*DA*DA*DA*DG*DC*DC*DC*DC*DT*DA*DG*DC*DTP*DT *DT*DT*DA*DG*DC*DT*DA*DT*DG*DG*DG*DGP)-3', 5'-D(*DT*DA*DT*DT*DA*DCP)-3', MAGNESIUM ION, ...
著者Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
登録日2007-12-13
公開日2008-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
1B6B
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BU of 1b6b by Molmil
MELATONIN BIOSYNTHESIS: THE STRUCTURE OF SEROTONIN N-ACETYLTRANSFERASE AT 2.5 A RESOLUTION SUGGESTS A CATALYTIC MECHANISM
分子名称: PROTEIN (ARYLALKYLAMINE N-ACETYLTRANSFERASE)
著者Hickman, A.B, Klein, D.C, Dyda, F.
登録日1999-01-13
公開日2000-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Melatonin biosynthesis: the structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism.
Mol.Cell, 3, 1999

 

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