8SGE
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![BU of 8sge by Molmil](/molmil-images/mine/8sge) | KLHDC2 Kelch Domain with ligand KDRLKZ-1 | Descriptor: | GLYCEROL, Kelch domain-containing protein 2, [(5P)-5-{3-[(2R)-butan-2-yl]-7-[(2-methoxyethoxy)carbonyl]-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl}-2-oxopyridin-1(2H)-yl]acetic acid | Authors: | Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K. | Deposit date: | 2023-04-12 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.509 Å) | Cite: | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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8SGF
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![BU of 8sgf by Molmil](/molmil-images/mine/8sgf) | KLHDC2 Kelch Domain with KLHDC2 c-terminal peptide bound | Descriptor: | GLYCEROL, HIS-SER-VAL-ASN-GLN-ARG-PHE-GLY-SER-ASN-ASN-THR-SER-GLY-SER, Kelch domain-containing protein 2 | Authors: | Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K. | Deposit date: | 2023-04-12 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.418 Å) | Cite: | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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8SH2
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![BU of 8sh2 by Molmil](/molmil-images/mine/8sh2) | KLHDC2 in complex with EloB and EloC | Descriptor: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | Authors: | Digianantonio, K.M, Bekes, M. | Deposit date: | 2023-04-13 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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7N9U
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![BU of 7n9u by Molmil](/molmil-images/mine/7n9u) | CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions | Descriptor: | Capsid protein, Nanobody | Authors: | Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y. | Deposit date: | 2021-06-18 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions To Be Published
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7N9X
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![BU of 7n9x by Molmil](/molmil-images/mine/7n9x) | CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions | Descriptor: | Capsid protein, Nanobody, Peptidyl-prolyl cis-trans isomerase A | Authors: | Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y. | Deposit date: | 2021-06-18 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.511 Å) | Cite: | CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions To Be Published
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7S2Y
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![BU of 7s2y by Molmil](/molmil-images/mine/7s2y) | SAMHD1 HD domain bound to CNDAC | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 4-amino-1-{2-cyano-2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | Authors: | Digianantonio, K.M, Xiong, Y. | Deposit date: | 2021-09-04 | Release date: | 2021-10-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells. J Exp Clin Cancer Res, 40, 2021
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6OBH
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![BU of 6obh by Molmil](/molmil-images/mine/6obh) | Structure of HIV-1 CA 1/2-hexamer | Descriptor: | CA, SODIUM ION | Authors: | Summers, B.J, Xiong, Y. | Deposit date: | 2019-03-20 | Release date: | 2019-08-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms. Cell Host Microbe, 26, 2019
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8H7E
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![BU of 8h7e by Molmil](/molmil-images/mine/8h7e) | Crystal structure of a de novo enzyme, ferric enterobactin esterase Syn-F4 (K4T) at 2.0 angstrom resolution | Descriptor: | ACETATE ION, De novo ferric enterobactin esterase Syn-F4 | Authors: | Kurihara, K, Umezawa, K, Donnelly, A.E, Hecht, M.H, Arai, R. | Deposit date: | 2022-10-19 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4. Proc.Natl.Acad.Sci.USA, 120, 2023
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8H7C
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![BU of 8h7c by Molmil](/molmil-images/mine/8h7c) | Crystal structure of a de novo enzyme, ferric enterobactin esterase Syn-F4 (K4T) - Pt derivative | Descriptor: | ACETATE ION, CHLORIDE ION, De novo ferric enterobactin esterase Syn-F4, ... | Authors: | Kurihara, K, Umezawa, K, Donnelly, A.E, Hecht, M.H, Arai, R. | Deposit date: | 2022-10-19 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4. Proc.Natl.Acad.Sci.USA, 120, 2023
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8H7D
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![BU of 8h7d by Molmil](/molmil-images/mine/8h7d) | Crystal structure of a de novo enzyme, ferric enterobactin esterase Syn-F4 (K4T) | Descriptor: | ACETATE ION, De novo ferric enterobactin esterase Syn-F4 | Authors: | Kurihara, K, Umezawa, K, Donnelly, A.E, Hecht, M.H, Arai, R. | Deposit date: | 2022-10-19 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4. Proc.Natl.Acad.Sci.USA, 120, 2023
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6MQO
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![BU of 6mqo by Molmil](/molmil-images/mine/6mqo) | Structure of HIV-1 CA G208R | Descriptor: | Capsid protein, IODIDE ION | Authors: | Smaga, S.S, Xiong, Y. | Deposit date: | 2018-10-10 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid. Structure, 27, 2019
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6MQA
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![BU of 6mqa by Molmil](/molmil-images/mine/6mqa) | Structure of HIV-1 CA P207S | Descriptor: | CHLORIDE ION, Capsid protein, IODIDE ION | Authors: | Smaga, S.S, Xiong, Y. | Deposit date: | 2018-10-09 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.199 Å) | Cite: | MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid. Structure, 27, 2019
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6MQP
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![BU of 6mqp by Molmil](/molmil-images/mine/6mqp) | Structure of HIV-1 CA T210K | Descriptor: | CHLORIDE ION, Capsid protein, IODIDE ION | Authors: | Smaga, S.S, Xiong, Y. | Deposit date: | 2018-10-10 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.296 Å) | Cite: | MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid. Structure, 27, 2019
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6ECN
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![BU of 6ecn by Molmil](/molmil-images/mine/6ecn) | HIV-1 CA 1/2-hexamer-EE | Descriptor: | HIV-1 CA | Authors: | Summers, B.J, Xiong, Y. | Deposit date: | 2018-08-08 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms. Cell Host Microbe, 26, 2019
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6EC2
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![BU of 6ec2 by Molmil](/molmil-images/mine/6ec2) | Structure of HIV-1 CA 1/3-hexamer | Descriptor: | ACETATE ION, Capsid protein p24 | Authors: | Summers, B.J, Xiong, Y. | Deposit date: | 2018-08-07 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms. Cell Host Microbe, 26, 2019
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6ECO
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![BU of 6eco by Molmil](/molmil-images/mine/6eco) | Hexamer-2-Foldon HIV-1 capsid platform | Descriptor: | HIV-1 capsid platform protein | Authors: | Summers, B.J, Xiong, Y. | Deposit date: | 2018-08-08 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms. Cell Host Microbe, 26, 2019
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