6C8G
| Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of barium | Descriptor: | BARIUM ION, Transient receptor potential cation channel, subfamily V, ... | Authors: | Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P. | Deposit date: | 2018-01-24 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (6.31 Å) | Cite: | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms. Nat. Struct. Mol. Biol., 25, 2018
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8WWO
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6V5A
| Crystal structure of the human BK channel gating ring L390P mutant | Descriptor: | CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, SULFATE ION | Authors: | Deng, Z, Yuan, P. | Deposit date: | 2019-12-03 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Coupling of Ca2+and voltage activation in BK channels through the alpha B helix/voltage sensor interface. Proc.Natl.Acad.Sci.USA, 117, 2020
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8IEJ
| RNF20-RNF40/hRad6A-Ub/nucleosome complex | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | Authors: | Ai, H, Deng, Z, Sun, M, Du, Y, Pan, M, Liu, L. | Deposit date: | 2023-02-15 | Release date: | 2023-09-06 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A. Mol.Cell, 83, 2023
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8IEG
| Bre1(mRBD-RING)/Rad6-Ub/nucleosome complex | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase BRE1, Histone H2A type 1-B/E, ... | Authors: | Ai, H, Deng, Z, Pan, M, Liu, L. | Deposit date: | 2023-02-15 | Release date: | 2023-09-06 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A. Mol.Cell, 83, 2023
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8J9Y
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8J9Z
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6JDR
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1BWK
| OLD YELLOW ENZYME (OYE1) MUTANT H191N | Descriptor: | FLAVIN MONONUCLEOTIDE, PROTEIN (NADPH DEHYDROGENASE 1) | Authors: | Brown, B.J, Deng, Z, Karplus, P.A, Massey, V. | Deposit date: | 1998-09-24 | Release date: | 1998-09-30 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | On the active site of Old Yellow Enzyme. Role of histidine 191 and asparagine 194. J.Biol.Chem., 273, 1998
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1BX0
| Ferredoxin:nadp+ oxidoreductase (ferredoxin reductase) mutant e312l | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ... | Authors: | Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G. | Deposit date: | 1998-10-10 | Release date: | 1998-10-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase. J.Biol.Chem., 273, 1998
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1BWL
| OLD YELLOW ENZYME (OYE1) DOUBLE MUTANT H191N:N194H | Descriptor: | FLAVIN MONONUCLEOTIDE, PROTEIN (NADPH DEHYDROGENASE 1) | Authors: | Brown, B.J, Deng, Z, Karplus, P.A, Massey, V. | Deposit date: | 1998-09-24 | Release date: | 1998-09-30 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | On the active site of Old Yellow Enzyme. Role of histidine 191 and asparagine 194. J.Biol.Chem., 273, 1998
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1BX1
| FERREDOXIN:NADP+ OXIDOREDUCTASE (FERREDOXIN REDUCTASE) MUTANT E312Q | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ... | Authors: | Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G. | Deposit date: | 1998-10-10 | Release date: | 1998-10-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase. J.Biol.Chem., 273, 1998
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1FRQ
| FERREDOXIN:NADP+ OXIDOREDUCTASE (FERREDOXIN REDUCTASE) MUTANT E312A | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ... | Authors: | Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G. | Deposit date: | 1998-10-10 | Release date: | 1998-10-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase. J.Biol.Chem., 273, 1998
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8D66
| ELIC with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-AMINO-ETHANETHIOL, Erwinia ligand-gated ion channel | Authors: | Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-23 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Nat Commun, 13, 2022
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8D65
| ELIC apo in 2:1:1 POPC:POPE:POPG nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Erwinia ligand-gated ion channel | Authors: | Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-23 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Nat Commun, 13, 2022
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8D63
| ELIC apo in POPC nanodisc | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Erwinia ligand-gated ion channel | Authors: | Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-23 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Nat Commun, 13, 2022
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8D64
| ELIC with cysteamine in POPC nanodisc | Descriptor: | 2-AMINO-ETHANETHIOL, Erwinia ligand-gated ion channel | Authors: | Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-23 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Nat Commun, 13, 2022
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8D67
| ELIC3 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc | Descriptor: | 2-AMINO-ETHANETHIOL, Erwinia ligand-gated ion channel | Authors: | Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-23 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Nat Commun, 13, 2022
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8VUW
| ELIC5 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc in open conformation | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-AMINO-ETHANETHIOL, Erwinia chrysanthemi ligand-gated ion channel | Authors: | Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L. | Deposit date: | 2024-01-29 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Nat Commun, 13, 2022
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3K3N
| Crystal structure of the catalytic core domain of human PHF8 | Descriptor: | FE (II) ION, PHD finger protein 8 | Authors: | Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z. | Deposit date: | 2009-10-03 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into a novel histone demethylase PHF8 Cell Res., 20, 2010
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3K3O
| Crystal structure of the catalytic core domain of human PHF8 complexed with alpha-ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, PHD finger protein 8 | Authors: | Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z. | Deposit date: | 2009-10-03 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into a novel histone demethylase PHF8 Cell Res., 20, 2010
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1HM1
| THE SOLUTION NMR STRUCTURE OF A THERMALLY STABLE FAPY ADDUCT OF AFLATOXIN B1 IN AN OLIGODEOXYNUCLEOTIDE DUPLEX REFINED FROM DISTANCE RESTRAINED MOLECULAR DYNAMICS SIMULATED ANNEALING, MINIMIZED AVERAGE STRUCTURE | Descriptor: | DNA (5'-D(*CP*TP*AP*TP*(FAG)P*AP*TP*TP*CP*A)-3'), DNA (5'-D(TP*GP*AP*AP*TP*CP*AP*TP*AP*G)-3') | Authors: | Mao, H, Deng, Z, Wang, F, Harris, T.M, Stone, M.P. | Deposit date: | 1998-05-11 | Release date: | 1998-10-14 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | An intercalated and thermally stable FAPY adduct of aflatoxin B1 in a DNA duplex: structural refinement from 1H NMR. Biochemistry, 37, 1998
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4P5A
| Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMP | Descriptor: | 5-BROMO-URIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase ThyX | Authors: | Li, Y, Chen, W, Li, J, Xia, Z, Deng, Z, Zhou, J. | Deposit date: | 2014-03-15 | Release date: | 2015-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi with 5-Br UMP To Be Published
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4P5B
| Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br dUMP | Descriptor: | 5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | Authors: | Li, Y, Chen, W, Li, J, Xia, Z, Deng, Z, Zhou, J. | Deposit date: | 2014-03-15 | Release date: | 2015-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.274 Å) | Cite: | Crystal structure of a UMP/dUMP methylase PolB form Streptomyces cacaoi bound with 5-Br dUMP To Be Published
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8GNA
| Structure of the SbCas7-11-crRNA-NTR complex | Descriptor: | RAMP superfamily protein, RNA (32-MER), RNA (5'-R(P*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*U)-3'), ... | Authors: | Yu, G, Wang, X, Deng, Z, Zhang, H. | Deposit date: | 2022-08-23 | Release date: | 2023-01-18 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Target RNA-guided protease activity in type III-E CRISPR-Cas system. Nucleic Acids Res., 50, 2022
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