6I08
 
 | | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C-I201W | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Hu, H.D, Delarue, M. | | 登録日 | 2018-10-25 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6HY9
 | | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193M | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel | | 著者 | Hu, H.D, Delarue, M. | | 登録日 | 2018-10-19 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8C5Z
 | | RPA tetrameric supercomplex with AROD-OB-1 | | 分子名称: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | | 著者 | Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L. | | 登録日 | 2023-01-10 | | 公開日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
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8C5Y
 | | RPA tetrameric supercomplex from Pyrococcus abyssi | | 分子名称: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | | 著者 | Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L. | | 登録日 | 2023-01-10 | | 公開日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
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8AAJ
 | | Crystal structure of the Pyrococcus abyssi RPA (apo form) | | 分子名称: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | | 著者 | Legrand, P, Madru, C, Sauguet, L. | | 登録日 | 2022-07-01 | | 公開日 | 2023-05-03 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
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8AAS
 | | Crystal structure of the Pyrococcus abyssi RPA trimerization core bound to poly-dT20 ssDNA | | 分子名称: | CALCIUM ION, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, ... | | 著者 | Madru, C, Legrand, P, Sauguet, L. | | 登録日 | 2022-07-01 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
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8AA9
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8OEJ
 | | Extended RPA-DNA nucleoprotein filament | | 分子名称: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | | 著者 | Madru, C, Martinez-Carranza, M, Sauguet, L. | | 登録日 | 2023-03-10 | | 公開日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (7.96 Å) | | 主引用文献 | DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
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8OEL
 | | Condensed RPA-DNA nucleoprotein filament | | 分子名称: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | | 著者 | Madru, C, Martinez-Carranza, M, Sauguet, L. | | 登録日 | 2023-03-10 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (8.24 Å) | | 主引用文献 | DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
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2QMI
 | | Structure of the octameric penicillin-binding protein homologue from Pyrococcus abyssi | | 分子名称: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, LUTETIUM (III) ION, Pbp related beta-lactamase | | 著者 | Delfosse, V, Girard, E, Moulinier, L, Schultz, P, Mayer, C. | | 登録日 | 2007-07-16 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the archaeal pab87 peptidase reveals a novel self-compartmentalizing protease family
Plos One, 4, 2009
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8PPV
 | | Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches | | 分子名称: | DNA (5'-D(*P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(G7P)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ... | | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | | 登録日 | 2023-07-10 | | 公開日 | 2023-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
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8PPU
 | | Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches | | 分子名称: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA polymerase II small subunit, ... | | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | | 登録日 | 2023-07-10 | | 公開日 | 2023-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
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8PPT
 | | Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing a mismatch | | 分子名称: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*GP*CP*TP*TP*T)-3'), DNA polymerase II small subunit, ... | | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | | 登録日 | 2023-07-10 | | 公開日 | 2023-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
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5IHE
 | | D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) | | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ACETATE ION, ... | | 著者 | Sauguet, L, Raia, P, De Larue, M. | | 登録日 | 2016-02-29 | | 公開日 | 2016-08-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography.
Nat Commun, 7, 2016
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5IJL
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3M4I
 | | Crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 1.95 A resolution | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit B | | 著者 | Piton, J, Petrella, S, Aubry, A, Mayer, C. | | 登録日 | 2010-03-11 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase.
Plos One, 5, 2010
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1B70
 | | PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE | | 分子名称: | MAGNESIUM ION, PHENYLALANINE, PHENYLALANYL-TRNA SYNTHETASE | | 著者 | Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G. | | 登録日 | 1999-01-26 | | 公開日 | 2000-02-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue
J.Mol.Biol., 287, 1999
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1B7Y
 | | PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINYL-ADENYLATE | | 分子名称: | ADENOSINE-5'-[PHENYLALANINOL-PHOSPHATE], MAGNESIUM ION, PROTEIN (PHENYLALANYL-TRNA SYNTHETASE) | | 著者 | Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G. | | 登録日 | 1999-01-26 | | 公開日 | 2000-01-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue.
J.Mol.Biol., 287, 1999
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1JJC
 | | Crystal structure at 2.6A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese | | 分子名称: | ADENOSINE-5'-[PHENYLALANINYL-PHOSPHATE], MANGANESE (II) ION, PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN, ... | | 著者 | Safro, M.G, Fishman, R, Moor, N, Ankilova, V. | | 登録日 | 2001-07-04 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure at 2.6 A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese.
Acta Crystallogr.,Sect.D, 57, 2001
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1PAX
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6HMS
 | | Cryo-EM map of DNA polymerase D from Pyrococcus abyssi in complex with DNA | | 分子名称: | DNA (5'-D(*GP*AP*GP*AP*CP*GP*GP*GP*CP*CP*GP*CP*GP*TP*C)-3'), DNA (5'-D(P*TP*GP*AP*CP*GP*CP*GP*GP*CP*CP*CP*GP*TP*CP*TP*C)-3'), DNA polymerase II large subunit,DNA polymerase II large subunit, ... | | 著者 | Raia, P, Carroni, M, Sauguet, L. | | 登録日 | 2018-09-12 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases.
PLoS Biol., 17, 2019
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1A26
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1MRS
 | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH 5-CH2OH DEOXYURIDINE MONOPHOSPHATE | | 分子名称: | 5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Haouz, A, Vanheusden, V, Munier-Lehmann, H, Froeyen, M, Herdewijn, P, Van Calenbergh, S, Delarue, M. | | 登録日 | 2002-09-18 | | 公開日 | 2003-01-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.
J.Biol.Chem., 278, 2003
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3PAX
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2PAX
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