1MRS
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH 5-CH2OH DEOXYURIDINE MONOPHOSPHATE
Summary for 1MRS
| Entry DOI | 10.2210/pdb1mrs/pdb |
| Related | 1G3U 1MRN |
| Descriptor | THYMIDYLATE KINASE, SULFATE ION, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | transferase (atp:tmp phosphotransferase), kinase, transferase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 23217.16 |
| Authors | Haouz, A.,Vanheusden, V.,Munier-Lehmann, H.,Froeyen, M.,Herdewijn, P.,Van Calenbergh, S.,Delarue, M. (deposition date: 2002-09-18, release date: 2003-01-07, Last modification date: 2024-02-14) |
| Primary citation | Haouz, A.,Vanheusden, V.,Munier-Lehmann, H.,Froeyen, M. Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism. J.Biol.Chem., 278:4963-4971, 2003 Cited by PubMed: 12454011DOI: 10.1074/jbc.M209630200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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