6I1D
 
 | | Structure of the Ysh1-Mpe1 nuclease complex from S.cerevisiae | | Descriptor: | Endoribonuclease YSH1, GLYCEROL, Protein MPE1, ... | | Authors: | Hill, C.H, Boreikaite, V, Kumar, A, Casanal, A, Kubik, P, Degliesposti, G, Maslen, S, Mariani, A, von Loeffelholz, O, Girbig, M, Skehel, M, Passmore, L.A. | | Deposit date: | 2018-10-28 | | Release date: | 2019-02-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex.
Mol.Cell, 73, 2019
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7B6H
 | | Drosophila melanogaster TRAPP C11 subunits region 1 to 718 | | Descriptor: | Trafficking protein particle complex subunit 11 | | Authors: | Galindo, A, Munro, S, Planelles-Herrero, V.J, Degliesposti, G. | | Deposit date: | 2020-12-07 | | Release date: | 2021-06-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (5.4 Å) | | Cite: | Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
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7B6E
 | | Drosophila melanogaster TRAPP C8 subunits region 355 to 661 | | Descriptor: | FI18195p1 | | Authors: | Galindo, A, Munro, S, Planelles-Herrero, V.J, Degliesposti, G. | | Deposit date: | 2020-12-07 | | Release date: | 2021-06-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
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7B6R
 | | Drosophila melanogaster TRAPPIII partial complex: core plus C8 and C11 attached region | | Descriptor: | FI18195p1, GEO08327p1, Probable trafficking protein particle complex subunit 2, ... | | Authors: | Galindo, A, Munro, S, Planelles-Herrero, V.J, Degliesposti, G. | | Deposit date: | 2020-12-08 | | Release date: | 2021-06-09 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
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7B6D
 | | Drosophila melanogaster TRAPPCore (C1, C2, C2L, C3a/b, C4, C5, C6 subunits) | | Descriptor: | GEO08327p1, Probable trafficking protein particle complex subunit 2, TRAPPC2L, ... | | Authors: | Galindo, A, Munro, S, Planelles-Herrero, V.J, Degliesposti, G. | | Deposit date: | 2020-12-07 | | Release date: | 2021-06-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (4.27 Å) | | Cite: | Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
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6EOJ
 | | PolyA polymerase module of the cleavage and polyadenylation factor (CPF) from Saccharomyces cerevisiae | | Descriptor: | Polyadenylation factor subunit 2,Polyadenylation factor subunit 2, Protein CFT1, ZINC ION, ... | | Authors: | Casanal, A, Kumar, A, Hill, C.H, Emsley, P, Passmore, L.A. | | Deposit date: | 2017-10-09 | | Release date: | 2017-11-15 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.55 Å) | | Cite: | Architecture of eukaryotic mRNA 3'-end processing machinery.
Science, 358, 2017
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6ZHX
 | | Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: nucleosome class. | | Descriptor: | Chromodomain-helicase-DNA-binding protein 1-like, DNA (145-MER) Widom 601 sequence, Histone H2A type 1, ... | | Authors: | Bacic, L, Gaullier, G, Croll, T.I, Deindl, S. | | Deposit date: | 2020-06-24 | | Release date: | 2020-12-23 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Cell Rep, 33, 2020
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6ZHY
 | | Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: hexasome class. | | Descriptor: | Chromodomain-helicase-DNA-binding protein 1-like, DNA (110-MER) Widom 601 sequence, Histone H2A type 1, ... | | Authors: | Bacic, L, Gaullier, G, Deindl, S. | | Deposit date: | 2020-06-24 | | Release date: | 2020-12-23 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Cell Rep, 33, 2020
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7OLE
 | | Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ... | | Authors: | Pal, M, Llorca, O, Pearl, L. | | Deposit date: | 2021-05-19 | | Release date: | 2021-07-07 | | Last modified: | 2021-10-06 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone.
Cell Rep, 36, 2021
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7P6X
 | | Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | | Authors: | Llorca, O, Serna, M, Fernandez-Leiro, R. | | Deposit date: | 2021-07-18 | | Release date: | 2021-12-15 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.
Nucleic Acids Res., 50, 2022
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5LNK
 | | Entire ovine respiratory complex I | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 4'-PHOSPHOPANTETHEINE, ... | | Authors: | Fiedorczuk, K, Letts, J.A, Kaszuba, K, Sazanov, L.A. | | Deposit date: | 2016-08-04 | | Release date: | 2016-11-23 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Atomic structure of the entire mammalian mitochondrial complex I.
Nature, 538, 2016
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6FO1
 | | Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ... | | Authors: | Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O. | | Deposit date: | 2018-02-05 | | Release date: | 2018-04-04 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
Nat Commun, 9, 2018
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5MQI
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6SGX
 | | Structure of protomer 1 of the ESX-3 core complex | | Descriptor: | ESX-3 secretion system EccB3, ESX-3 secretion system protein EccC3, ESX-3 secretion system protein EccD3, ... | | Authors: | Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S. | | Deposit date: | 2019-08-05 | | Release date: | 2019-10-09 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
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6SGY
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6SGW
 | | Structure of the ESX-3 core complex | | Descriptor: | ESX-3 secretion system ATPase EccB3, ESX-3 secretion system protein EccC3, ESX-3 secretion system protein EccD3, ... | | Authors: | Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S. | | Deposit date: | 2019-08-05 | | Release date: | 2019-10-09 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
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6SRI
 | | Structure of the Fanconi anaemia core complex | | Descriptor: | Fanconi anaemia protein FANCL, Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), ... | | Authors: | Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A. | | Deposit date: | 2019-09-05 | | Release date: | 2019-11-06 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
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6SRS
 | | Structure of the Fanconi anaemia core subcomplex | | Descriptor: | Fanconi anaemia protein FANCL, Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), ... | | Authors: | Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A. | | Deposit date: | 2019-09-05 | | Release date: | 2019-11-06 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
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6SGZ
 | | Structure of protomer 2 of the ESX-3 core complex | | Descriptor: | ESX-3 secretion system ATPase EccB3, ESX-3 secretion system protein EccC3, ESX-3 secretion system protein EccD3, ... | | Authors: | Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S. | | Deposit date: | 2019-08-05 | | Release date: | 2019-10-09 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
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7B70
 | | TRAPPCore plus C8 (355-596) and C11 (1-718) from MiniTRAPPIII | | Descriptor: | FI18195p1, GEO08327p1, Probable trafficking protein particle complex subunit 2, ... | | Authors: | Galindo, A, Munro, S, Planelles-Herrero, V.J. | | Deposit date: | 2020-12-09 | | Release date: | 2021-06-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
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7B6X
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7B6Y
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7B6Z
 | | TRAPPC11 subunit (1-716) | | Descriptor: | Trafficking protein particle complex subunit 11 | | Authors: | Galindo, A, Munro, S, Planelles-Herrero, V.J. | | Deposit date: | 2020-12-08 | | Release date: | 2022-01-12 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Structural insights into the metazoan TRAPP complexes that activate Rab1 and
Rab11.
To Be Published
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6QA9
 | | Isolated complex I class refinement from Ovine respiratory supercomplex I+III2 | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | Authors: | Letts, J.A, Sazanov, L.A. | | Deposit date: | 2018-12-19 | | Release date: | 2019-08-21 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
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6QC8
 | | Ovine respiratory complex I FRC open class 2 | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | Authors: | Letts, J.A, Sazanov, L.A. | | Deposit date: | 2018-12-27 | | Release date: | 2019-08-21 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
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