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5EKU
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BU of 5eku by Molmil
Crystal Structure of Trypanosoma Brucei Protein Arginine Methyltransferase PRMT7 in complex with S-Adenosyl-L-homocysteine
分子名称: Arginine N-methyltransferase, putative, S-ADENOSYL-L-HOMOCYSTEINE
著者Debler, E.W, Stavropoulos, P.
登録日2015-11-04
公開日2016-05-18
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase.
Proc.Natl.Acad.Sci.USA, 113, 2016
2NTF
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BU of 2ntf by Molmil
Crystal Structure of a Quorum-Quenching Antibody in Complex with an N-Acyl-L-Homoserine Lactone Analog
分子名称: 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
著者Debler, E.W, Wilson, I.A.
登録日2006-11-07
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
1Y18
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BU of 1y18 by Molmil
Fab fragment of catalytic elimination antibody 34E4 E(H50)D mutant in complex with hapten
分子名称: 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic antibody 34E4 heavy chain, ...
著者Debler, E.W, Ito, S, Heine, A, Wilson, I.A.
登録日2004-11-17
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Proc.Natl.Acad.Sci.USA, 102, 2005
1Y0L
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BU of 1y0l by Molmil
Catalytic elimination antibody 34E4 in complex with hapten
分子名称: 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic Antibody Fab 34E4 Heavy chain, ...
著者Debler, E.W, Ito, S, Heine, A, Wilson, I.A.
登録日2004-11-15
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Proc.Natl.Acad.Sci.USA, 102, 2005
3CFJ
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BU of 3cfj by Molmil
Crystal structure of catalytic elimination antibody 34E4, orthorhombic crystal form
分子名称: CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN fusion, CATALYTIC ANTIBODY FAB 34E4 LIGHT CHAIN fusion, GLYCEROL, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-04
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
3CFE
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BU of 3cfe by Molmil
Crystal structure of purple-fluorescent antibody EP2-25C10
分子名称: GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-KAPPA LIGHT CHAIN, ...
著者Debler, E.W, Heine, A, Wilson, I.A.
登録日2008-03-03
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3CFK
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BU of 3cfk by Molmil
Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN,Uncharacterized protein, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-04
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
3CFD
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BU of 3cfd by Molmil
Purple-fluorescent antibody EP2-25C10 in complex with its stilbene hapten
分子名称: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, ...
著者Debler, E.W, Heine, A, Wilson, I.A.
登録日2008-03-03
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3CFC
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BU of 3cfc by Molmil
High-resolution structure of blue fluorescent antibody EP2-19G2
分子名称: BLUE FLUORESCENT ANTIBODY EP2-19G2-IGG2B HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY EP2-19G2-KAPPA LIGHT CHAIN, GLYCEROL
著者Debler, E.W, Wilson, I.A.
登録日2008-03-03
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3CFB
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BU of 3cfb by Molmil
High-resolution structure of blue fluorescent antibody EP2-19G2 in complex with stilbene hapten at 100K
分子名称: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, BLUE FLUORESCENT ANTIBODY EP2-19G2-IGG2B HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY EP2-19G2-KAPPA LIGHT CHAIN, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-03
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3F3P
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BU of 3f3p by Molmil
Crystal structure of the nucleoporin pair Nup85-Seh1, space group P21212
分子名称: Nucleoporin NUP85, Nucleoporin SEH1
著者Debler, E.W, Hseo, H, Ma, Y, Blobel, G, Hoelz, A.
登録日2008-10-31
公開日2009-04-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A fence-like coat for the nuclear pore membrane.
Mol.Cell, 32, 2008
3F3F
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BU of 3f3f by Molmil
Crystal structure of the nucleoporin pair Nup85-Seh1, space group P21
分子名称: Nucleoporin NUP85, Nucleoporin SEH1
著者Debler, E.W, Hseo, H, Ma, Y, Blobel, G, Hoelz, A.
登録日2008-10-30
公開日2009-04-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A fence-like coat for the nuclear pore membrane.
Mol.Cell, 32, 2008
3FO2
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BU of 3fo2 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Gln mutant)
分子名称: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
著者Debler, E.W, Wilson, I.A.
登録日2008-12-27
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F3G
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BU of 3f3g by Molmil
Crystal structure of the nucleoporin pair Nup85-Seh1, space group P212121
分子名称: Nucleoporin NUP85, Nucleoporin SEH1
著者Debler, E.W, Hseo, H, Ma, Y, Blobel, G, Hoelz, A.
登録日2008-10-30
公開日2009-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献A fence-like coat for the nuclear pore membrane.
Mol.Cell, 32, 2008
3FO1
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BU of 3fo1 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Ala mutant)
分子名称: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
著者Debler, E.W, Wilson, I.A.
登録日2008-12-27
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3FO0
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BU of 3fo0 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (wild-type)
分子名称: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-12-27
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
4PKL
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BU of 4pkl by Molmil
Bromodomain of Trypanosoma brucei BDF2 With IBET-151
分子名称: 7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE, Bromodomain factor 2, CHLORIDE ION, ...
著者Debler, E.W.
登録日2014-05-15
公開日2015-11-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.251 Å)
主引用文献Bromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome.
Plos Biol., 13, 2015
3PBP
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BU of 3pbp by Molmil
Structure of the yeast heterotrimeric Nup82-Nup159-Nup116 nucleoporin complex
分子名称: Nucleoporin NUP116/NSP116, Nucleoporin NUP159, Nucleoporin NUP82, ...
著者Debler, E.W, Hoelz, A.
登録日2010-10-20
公開日2011-10-26
最終更新日2011-11-02
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
2OP4
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BU of 2op4 by Molmil
Crystal Structure of Quorum-Quenching Antibody 1G9
分子名称: 1,2-ETHANEDIOL, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
著者Kirchdoerfer, R.N, Debler, E.W, Wilson, I.A.
登録日2007-01-26
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
2ERJ
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BU of 2erj by Molmil
Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Debler, E.W, Stauber, D.J, Wilson, I.A.
登録日2005-10-25
公開日2006-02-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2G2R
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BU of 2g2r by Molmil
Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)
分子名称: Green-fluorescent antibody (11G10)-heavy chain, Green-fluorescent antibody (11G10)-light chain, N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID, ...
著者Debler, E.W, Wilson, I.A.
登録日2006-02-16
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The Effects of Antibodies on Stilbene Excited-State Energetics.
Angew.Chem.Int.Ed.Engl., 45, 2006
2GJZ
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BU of 2gjz by Molmil
Structure of Catalytic Elimination Antibody 13G5 from a crystal in space group P2(1)
分子名称: Catalytic elimination antibody 13G5 heavy chain, Catalytic elimination antibody 13G5 light chain, ZINC ION
著者Debler, E.W, Wilson, I.A.
登録日2006-03-31
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Bifunctional Catalysis of Proton Transfer at an Antibody Active Site.
J.Am.Chem.Soc., 129, 2007
2GK0
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BU of 2gk0 by Molmil
Structure of Catalytic Elimination Antibody 13G5 from a twinned crystal in space group C2
分子名称: Catalytic elimination antibody 13G5 heavy chain, Catalytic elimination antibody 13G5 light chain
著者Debler, E.W, Wilson, I.A.
登録日2006-03-31
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Bifunctional Catalysis of Proton Transfer at an Antibody Active Site.
J.Am.Chem.Soc., 129, 2007
6DNZ
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BU of 6dnz by Molmil
Trypanosoma brucei PRMT1 enzyme-prozyme heterotetrameric complex with AdoHcy
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arginine N-methyltransferase, putative, ...
著者Hashimoto, H, Kafkova, L, Jordan, K, Read, L.K, Debler, E.W.
登録日2018-06-08
公開日2019-06-12
最終更新日2020-02-12
実験手法X-RAY DIFFRACTION (2.384 Å)
主引用文献Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme).
J.Mol.Biol., 432, 2020
6OFP
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BU of 6ofp by Molmil
Structure of the C-terminal cargo binding domain of human Bicaudal D2
分子名称: Protein bicaudal D homolog 2
著者Noell, C.R, Debler, E.W, Cui, H, Solmaz, S.R.
登録日2019-03-31
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Role of Coiled-Coil Registry Shifts in the Activation of Human Bicaudal D2 for Dynein Recruitment upon Cargo Binding.
J Phys Chem Lett, 10, 2019

 

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