5V6C
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![BU of 5v6c by Molmil](/molmil-images/mine/5v6c) | Crystal Structure of the Second beta-Prism Domain of RbmC from V. cholerae | Descriptor: | GLYCEROL, Hemolysin-related protein | Authors: | De, S, Kaus, K, Sinclair, S, Case, B.C, Olson, R. | Deposit date: | 2017-03-16 | Release date: | 2018-01-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of mammalian glycan targeting by Vibrio cholerae cytolysin and biofilm proteins. PLoS Pathog., 14, 2018
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3O44
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![BU of 3o44 by Molmil](/molmil-images/mine/3o44) | |
2MD5
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![BU of 2md5 by Molmil](/molmil-images/mine/2md5) | Structure of uninhibited ETV6 ETS domain | Descriptor: | Transcription factor ETV6 | Authors: | De, S, Mcintosh, L.P, Chan, A.C, Coyne, H.J, Okon, M, Graves, B.J, Murphy, M.E. | Deposit date: | 2013-08-29 | Release date: | 2013-12-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6. J.Mol.Biol., 426, 2014
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5V6F
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![BU of 5v6f by Molmil](/molmil-images/mine/5v6f) | Crystal Structure of the Second beta-Prism Domain of RbmC from V. cholerae bound to Mannotriose | Descriptor: | Hemolysin-related protein, SULFATE ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose | Authors: | De, S, Kaus, K, Sinclair, S, Case, B.C, Olson, R. | Deposit date: | 2017-03-16 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of mammalian glycan targeting by Vibrio cholerae cytolysin and biofilm proteins. PLoS Pathog., 14, 2018
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5V6K
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![BU of 5v6k by Molmil](/molmil-images/mine/5v6k) | Crystal Structure of the Second beta-Prism Domain of RbmC from V. cholerae Bound to N-acetylglucosaminyl-beta-1,2-mannose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, GLYCEROL, Hemolysin-related protein | Authors: | De, S, Kaus, K, Sinclair, S, Case, B.C, Olson, R. | Deposit date: | 2017-03-16 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of mammalian glycan targeting by Vibrio cholerae cytolysin and biofilm proteins. PLoS Pathog., 14, 2018
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5D13
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![BU of 5d13 by Molmil](/molmil-images/mine/5d13) | |
4MHG
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![BU of 4mhg by Molmil](/molmil-images/mine/4mhg) | Crystal structure of ETV6 bound to a specific DNA sequence | Descriptor: | Complementary Specific 14 bp DNA, Specific 14 bp DNA, Transcription factor ETV6 | Authors: | Chan, A.C, De, S, Coyne III, H.J, Okon, M, Murphy, M.E, Graves, B.J, McIntosh, L.P. | Deposit date: | 2013-08-29 | Release date: | 2014-01-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6. J.Mol.Biol., 426, 2014
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7SYN
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![BU of 7syn by Molmil](/molmil-images/mine/7syn) | Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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7SYJ
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![BU of 7syj by Molmil](/molmil-images/mine/7syj) | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYL
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![BU of 7syl by Molmil](/molmil-images/mine/7syl) | Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYX
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![BU of 7syx by Molmil](/molmil-images/mine/7syx) | Structure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S24, 40S ribosomal protein S25, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYW
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![BU of 7syw by Molmil](/molmil-images/mine/7syw) | Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(wt) | Descriptor: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYG
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![BU of 7syg by Molmil](/molmil-images/mine/7syg) | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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7SYI
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![BU of 7syi by Molmil](/molmil-images/mine/7syi) | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYM
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![BU of 7sym by Molmil](/molmil-images/mine/7sym) | Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway To Be Published
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7EB1
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![BU of 7eb1 by Molmil](/molmil-images/mine/7eb1) | Solution NMR structure of the RRM domain of RNA binding protein RBM3 from homo sapiens | Descriptor: | RNA-binding protein 3 | Authors: | Boral, S, Roy, S, Basak, A.J, Maiti, S, Lee, W, De, S. | Deposit date: | 2021-03-08 | Release date: | 2021-12-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural and dynamic studies of the human RNA binding protein RBM3 reveals the molecular basis of its oligomerization and RNA recognition. Febs J., 289, 2022
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7CFV
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![BU of 7cfv by Molmil](/molmil-images/mine/7cfv) | |
6UU8
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![BU of 6uu8 by Molmil](/molmil-images/mine/6uu8) | E. coli mutant sigma-S transcription initiation complex with a 7-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, and CTP for 30 minutes) | Descriptor: | DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UTW
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![BU of 6utw by Molmil](/molmil-images/mine/6utw) | E. coli sigma-S transcription initiation complex with a 4-nt RNA ("Fresh" crystal) | Descriptor: | DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.854 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UU0
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![BU of 6uu0 by Molmil](/molmil-images/mine/6uu0) | E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UU6
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![BU of 6uu6 by Molmil](/molmil-images/mine/6uu6) | E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.201 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UU1
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![BU of 6uu1 by Molmil](/molmil-images/mine/6uu1) | E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes) | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.097 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UTZ
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![BU of 6utz by Molmil](/molmil-images/mine/6utz) | E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP and UTP for 30 minutes) | Descriptor: | DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.803 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UTY
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![BU of 6uty by Molmil](/molmil-images/mine/6uty) | E. coli sigma-S transcription initiation complex with a mismatching CTP ("Old" crystal soaked with CTP for 30 minutes) | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UTX
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![BU of 6utx by Molmil](/molmil-images/mine/6utx) | E. coli sigma-S transcription initiation complex with an empty bubble ("Old" crystal) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.05 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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