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1LMM
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Solution Structure of Psmalmotoxin 1, the First Characterized Specific Blocker of ASIC1a NA+ channel
Descriptor: Psalmotoxin 1
Authors:Escoubas, P, Bernard, C, Lazdunski, M, Darbon, H.
Deposit date:2002-05-02
Release date:2003-11-25
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels
Protein Sci., 12, 2003
1LMR
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Solution of ADO1, a Toxin from the Assassin Bugs Agriosphodrus dohrni that Blocks the Voltage Sensitive Calcium Channel L-type
Descriptor: TOXIN ADO1
Authors:Bernard, C, Corzo, G, Adachi-Akahane, S, Foures, G, Kanemaru, K, Furukawa, Y, Nakajima, T, Darbon, H.
Deposit date:2002-05-02
Release date:2003-08-19
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of ADO1, a toxin extracted from the saliva of the assassin bug, Agriosphodrus dohrni
Proteins: STRUCT.,FUNCT.,GENET., 54, 2004
1TSK
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BU of 1tsk by Molmil
SCORPION TOXIN (TS KAPPA) FROM TITYUS SERRULATUS ACTIVE ON SMALL CONDUCTANCE POTASSIUM CHANNEL, NMR, 30 STRUCTURES
Descriptor: TS KAPA
Authors:Blanc, E, Darbon, H.
Deposit date:1997-02-05
Release date:1997-08-12
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of TsKapa, a charybdotoxin-like scorpion toxin from Tityus serrulatus with high affinity for apamin-sensitive Ca(2+)-activated K+ channels.
Proteins, 29, 1997
1TXM
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SCORPION TOXIN (MAUROTOXIN) FROM SCORPIO MAURUS, NMR, 35 STRUCTURES
Descriptor: MAUROTOXIN
Authors:Blanc, E, Sabatier, J.-M, Kharrat, R, Meunier, S, El Ayeb, M, Van Rietschoten, J, Darbon, H.
Deposit date:1996-11-19
Release date:1997-06-05
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels.
Proteins, 29, 1997
1V90
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BU of 1v90 by Molmil
Solution structure by NMR means of delta-paluIT1-NH2
Descriptor: Delta-palutoxin IT1
Authors:Ferrat, G, Bosmans, F, Tytgat, J, Pimentel, C, Chagot, B, Nakajima, T, Darbon, H, Corzo, G.
Deposit date:2004-01-19
Release date:2005-03-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na(+) channel
Proteins, 59, 2005
1V91
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Solution structure of insectidal toxin delta-paluIT2-NH2
Descriptor: Delta-palutoxin IT2
Authors:Ferrat, G, Bosmans, F, Tytgat, J, Pimentel, C, Chagot, B, Nakajima, T, Darbon, H, Corzo, G.
Deposit date:2004-01-19
Release date:2005-03-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na(+) channel
Proteins, 59, 2005
1V7F
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Solution structure of phrixotoxin 1
Descriptor: Phrixotoxin 1
Authors:Chagot, B, Escoubas, P, Villegas, E, Bernard, C, Ferrat, G, Corzo, G, Lazdunski, M, Darbon, H.
Deposit date:2003-12-16
Release date:2004-11-23
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus
Protein Sci., 13, 2004
1WPD
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Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
Descriptor: Potassium channel toxin alpha-KTx 6.2,Potassium channel toxin alpha-KTx 6.3
Authors:Regaya, I, Beeton, C, Ferrat, G, Andreotti, N, Chandy, G.K, Darbon, H, De Waard, M, Sabatier, J.M.
Deposit date:2004-09-01
Release date:2004-10-19
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
J.Biol.Chem., 279, 2004
1WQE
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An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Descriptor: OmTx3
Authors:Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G.
Deposit date:2004-09-28
Release date:2005-01-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
1WQC
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An unusual fold for potassium channel blockers : NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Descriptor: OmTx1
Authors:Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G.
Deposit date:2004-09-27
Release date:2005-01-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
1WT7
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Solution structure of BuTX-MTX: a butantoxin-maurotoxin chimera
Descriptor: BuTX-MTX
Authors:M'Barek, S, Chagot, B, Andreotti, N, Visan, V, Mansuelle, P, Grissmer, S, Marrakchi, M, El Ayeb, M, Sampieri, F, Darbon, H, Fajloun, Z, De Waard, M, Sabatier, J.-M.
Deposit date:2004-11-16
Release date:2004-11-30
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.
Proteins, 60, 2005
1WQK
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Solution structure of APETx1, a specific peptide inhibitor of human Ether-a-go-go-related gene potassium channels from the venom of the sea anemone Anthopleura elegantissima: a new fold for an HERG toxin
Descriptor: Toxin APETx1
Authors:Chagot, B, Diochot, S, Pimentel, C, Lazdunski, M, Darbon, H.
Deposit date:2004-09-30
Release date:2005-03-08
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin
Proteins, 59, 2005
1WXN
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Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
Descriptor: Toxin APETx2
Authors:Chagot, B, Escoubas, P, Diochot, S, Bernard, C, Lazdunski, M, Darbon, H.
Deposit date:2005-01-27
Release date:2005-08-16
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
Protein Sci., 14, 2005
1WO9
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Selective inhibition of trypsins by insect peptides: role of P6-P10 loop
Descriptor: trypsin inhibitor
Authors:Kellenberger, C, Ferrat, G, Leone, P, Darbon, H, Roussel, A.
Deposit date:2004-08-12
Release date:2004-09-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Selective inhibition of trypsins by insect peptides: role of P6-P10 loop
Biochemistry, 42, 2003
1X5V
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BU of 1x5v by Molmil
NMR Structure of PcFK1
Descriptor: PcFK1
Authors:Pimentel, C, Choi, S.J, Chagot, B, Guette, C, Camadro, J.M, Darbon, H.
Deposit date:2005-05-17
Release date:2006-04-04
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum
Protein Sci., 15, 2006
1WQD
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An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Descriptor: OmTx2
Authors:Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G.
Deposit date:2004-09-28
Release date:2005-01-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
1Y2P
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Solution structure of Hstx3P
Descriptor: Neurotoxin HsTX1
Authors:Mosbah, A, Gariga, L, Darbon, H, Sabatier, J.M.
Deposit date:2004-11-23
Release date:2005-11-01
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily
Proteins, 61, 2005
1GMM
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BU of 1gmm by Molmil
Carbohydrate binding module CBM6 from xylanase U Clostridium thermocellum
Descriptor: CALCIUM ION, CBM6, SODIUM ION, ...
Authors:Czjzek, M, Mosbah, A, Bolam, D, Allouch, J, Zamboni, V, Henrissat, B, Gilbert, H.J.
Deposit date:2001-09-19
Release date:2001-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Location of the Ligand-Binding Site of Carbohydrate-Binding Modules that Have Evolved from a Common Sequence is not Conserved.
J.Biol.Chem., 276, 2001
2MUB
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BU of 2mub by Molmil
Solution structure of the analgesic sea anemone peptide APETx2
Descriptor: Toxin APETx2
Authors:Mobli, M, King, G.F, Rosengren, K.J, Jensen, J.E.
Deposit date:2014-09-07
Release date:2014-12-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores.
J.Med.Chem., 57, 2014
1WZ5
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Solution structure of Pi1-3p
Descriptor: Potassium channel blocking toxin 1
Authors:Ferrat, G.
Deposit date:2005-02-24
Release date:2005-04-19
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily
Proteins, 61, 2005
1GOE
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BU of 1goe by Molmil
Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.
Descriptor: CORTICOTROPIN RELEASING HORMONE
Authors:Spyroulias, G.A, Papazacharias, S, Pairas, G, Cordopatis, P.
Deposit date:2001-10-20
Release date:2001-10-31
Last modified:2015-10-21
Method:SOLUTION NMR
Cite:Monitoring the Structural Consequences of Phe12-->D-Phe and Leu15-->Aib Substitution in Human/Rat Corticotropin Releasing Hormone
Eur.J.Biochem., 269, 2002
1GO9
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Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.
Descriptor: CORTICOTROPIN RELEASING HORMONE
Authors:Spyroulias, G.A, Papazacharias, S, Pairas, G, Cordopatis, P.
Deposit date:2001-10-20
Release date:2001-10-31
Last modified:2016-12-21
Method:SOLUTION NMR
Cite:Monitoring the Structural Consequences of Phe12-->D-Phe and Leu15-->Aib Substitution in Human/Rat Corticotropin Releasing Hormone. Implications for Design of Crh Antagonists.
Eur.J.Biochem., 269, 2002
2KNI
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High-resolution solution structure of the ASIC1a blocker PcTX1
Descriptor: Psalmotoxin-1
Authors:King, G.F, Mobli, M, Saez, N.J.
Deposit date:2009-08-25
Release date:2010-09-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a.
Mol.Pharmacol., 80, 2011
1KX9
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ANTENNAL CHEMOSENSORY PROTEIN A6 FROM THE MOTH MAMESTRA BRASSICAE
Descriptor: ACETATE ION, CHEMOSENSORY PROTEIN A6
Authors:Lartigue, A, Campanacci, V, Roussel, A, Larsson, A.M, Jones, T.A, Tegoni, M, Cambillau, C.
Deposit date:2002-01-31
Release date:2002-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:X-ray structure and ligand binding study of a moth chemosensory protein
J.Biol.Chem., 277, 2002
1KX8
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Antennal Chemosensory Protein A6 from Mamestra brassicae, tetragonal form
Descriptor: CHEMOSENSORY PROTEIN A6
Authors:Lartigue, A, Campanacci, V, Roussel, A, Larsson, A.M, Jones, T.A, Tegoni, M, Cambillau, C.
Deposit date:2002-01-31
Release date:2002-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-Ray Structure and Ligand Binding Study of a Chemosensory Protein
J.Biol.Chem., 277, 2002
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