Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4UIB
DownloadVisualize
BU of 4uib by Molmil
Crystal structure of 3p in complex with tafCPB
Descriptor: (2S)-6-AMINO-2-[[(1R)-1-(CYCLOHEXYLMETHYL)-2-OXO-2-[[(2S)-1,7,7-TRIMETHYLNORBORNAN-2-YL]AMINO]ETHYL]ARBAMOYLAMINO]HEXANOIC ACID, ACETATE ION, CARBOXYPEPTIDASE B, ...
Authors:Halland, N, Broenstrup, M, Czech, J, Czechtizky, W, Evers, A, Follmann, M, Kohlmann, M, Schiell, M, Kurz, M, Schreuder, H.A, Kallus, C.
Deposit date:2015-03-27
Release date:2015-06-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (Tafia) from Natural Product Anabaenopeptin.
J.Med.Chem., 58, 2015
4UIA
DownloadVisualize
BU of 4uia by Molmil
Crystal structure of 3a in complex with tafCPB
Descriptor: (2S)-6-azanyl-2-[[(2R)-3-cyclohexyl-1-(3-methylbutylamino)-1-oxidanylidene-propan-2-yl]carbamoylamino]hexanoic acid, CARBOXYPEPTIDASE B, ZINC ION
Authors:Halland, N, Broenstrup, M, Czech, J, Czechtizky, W, Evers, A, Follmann, M, Kohlmann, M, Schiell, M, Kurz, M, Schreuder, H.A, Kallus, C.
Deposit date:2015-03-27
Release date:2015-06-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (Tafia) from Natural Product Anabaenopeptin.
J.Med.Chem., 58, 2015
5LYI
DownloadVisualize
BU of 5lyi by Molmil
Crystal structure of 1 in complex with tafCPB
Descriptor: (2~{S})-6-azanyl-2-[[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(1~{R},2~{S},4~{R})-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]amino]propan-2-yl]sulfamoylamino]hexanoic acid, Carboxypeptidase B, ZINC ION
Authors:Schreuder, H, Liesum, A, Loenze, P.
Deposit date:2016-09-28
Release date:2016-10-26
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Sulfamide as Zinc Binding Motif in Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa).
J. Med. Chem., 59, 2016
5LYF
DownloadVisualize
BU of 5lyf by Molmil
Crystal structure of 1 in complex with tafCPB
Descriptor: (2~{S})-6-azanyl-2-[[(2~{R})-1-[[(1~{R},2~{S},4~{S})-2-bicyclo[2.2.1]heptanyl]amino]-3-cyclohexyl-1-oxidanylidene-propan-2-yl]carbamoylamino]hexanoic acid, Carboxypeptidase B, ZINC ION
Authors:Schreuder, H, Liesum, A, Loenze, P.
Deposit date:2016-09-28
Release date:2016-10-26
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Sulfamide as Zinc Binding Motif in Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa).
J. Med. Chem., 59, 2016
5LYD
DownloadVisualize
BU of 5lyd by Molmil
Crystal structure of 1 in complex with tafCPB
Descriptor: (2~{S})-6-azanyl-2-(sulfamoylamino)hexanoic acid, Carboxypeptidase B, ZINC ION
Authors:Schreuder, H, Liesum, A, Loenze, P.
Deposit date:2016-09-27
Release date:2016-10-26
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Sulfamide as Zinc Binding Motif in Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa).
J. Med. Chem., 59, 2016
5LYL
DownloadVisualize
BU of 5lyl by Molmil
Crystal structure of 1 in complex with tafCPB
Descriptor: (2~{S})-2-[[(2~{S})-1-(1-adamantylamino)-3-cyclohexyl-1-oxidanylidene-propan-2-yl]sulfamoylamino]-6-azanyl-hexanoic acid, Carboxypeptidase B, ZINC ION
Authors:Schreuder, H, Liesum, A, Loenze, P.
Deposit date:2016-09-28
Release date:2016-10-26
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Sulfamide as Zinc Binding Motif in Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa).
J. Med. Chem., 59, 2016
4IAN
DownloadVisualize
BU of 4ian by Molmil
Crystal Structure of apo Human PRPF4B kinase domain
Descriptor: SULFATE ION, Serine/threonine-protein kinase PRP4 homolog
Authors:Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
Deposit date:2012-12-06
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
4IIR
DownloadVisualize
BU of 4iir by Molmil
Crystal Structure of AMPPNP-bound Human PRPF4B kinase domain
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ...
Authors:Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
Deposit date:2012-12-20
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
4IFC
DownloadVisualize
BU of 4ifc by Molmil
Crystal Structure of ADP-bound Human PRPF4B kinase domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog
Authors:Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
Deposit date:2012-12-14
Release date:2013-08-28
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
4IJP
DownloadVisualize
BU of 4ijp by Molmil
Crystal Structure of Human PRPF4B kinase domain in complex with 4-{5-[(2-Chloro-pyridin-4-ylmethyl)-carbamoyl]-thiophen-2-yl}-benzo[b]thiophene-2-carboxylic acid amine
Descriptor: 4-(5-{[(2-chloropyridin-4-yl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog
Authors:Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
Deposit date:2012-12-22
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013

219140

PDB entries from 2024-05-01

PDB statisticsPDBj update infoContact PDBjnumon