4UIB

Crystal structure of 3p in complex with tafCPB

Summary for 4UIB

Entry DOI	10.2210/pdb4uib/pdb
Related	4UIA
Descriptor	CARBOXYPEPTIDASE B, ZINC ION, ACETATE ION, ... (6 entities in total)
Functional Keywords	hydrolase, tafi, thrombosis, fibrinolysis, drug discovery
Biological source	SUS SCROFA (PIG)
Cellular location	Secreted : P09955
Total number of polymer chains	1
Total formula weight	35962.28
Authors	Halland, N.,Broenstrup, M.,Czech, J.,Czechtizky, W.,Evers, A.,Follmann, M.,Kohlmann, M.,Schiell, M.,Kurz, M.,Schreuder, H.A.,Kallus, C. (deposition date: 2015-03-27, release date: 2015-06-03, Last modification date: 2017-09-27)
Primary citation	Halland, N.,Bronstrup, M.,Czech, J.,Czechtizky, W.,Evers, A.,Follmann, M.,Kohlmann, M.,Schiell, M.,Kurz, M.,Schreuder, H.A.,Kallus, C. Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (Tafia) from Natural Product Anabaenopeptin. J.Med.Chem., 58:4839-, 2015 Cited by PubMed: 25990761 DOI: 10.1021/JM501840B PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.94 Å)

Structure validation