1H2V
| Structure of the human nuclear cap-binding-complex (CBC) | Descriptor: | 20 KDA NUCLEAR CAP BINDING PROTEIN, 80 KDA NUCLEAR CAP BINDING PROTEIN | Authors: | Mazza, C, Segref, A, Mattaj, I.W, Cusack, S. | Deposit date: | 2002-08-16 | Release date: | 2002-10-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Large-Scale Induced Fit Recognition of an M(7)Gpppg CAP Analogue by the Human Nuclear CAP-Binding Complex Embo J., 21, 2002
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5FMZ
| Crystal structure of Influenza B polymerase with bound 5' vRNA | Descriptor: | 5'-R(*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP)-3', POLYMERASE ACIDIC PROTEIN, POLYMERASE BASIC PROTEIN 2, ... | Authors: | Guilligay, D, Cusack, S. | Deposit date: | 2015-11-10 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains. Mol.Cell, 61, 2016
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1E6O
| Crystal structure of Fab13B5 against HIV-1 capsid protein p24 | Descriptor: | IMMUNOGLOBULIN HEAVY CHAIN, IMMUNOGLOBULIN LIGHT CHAIN | Authors: | Monaco-Malbet, S, Berthet-Colominas, C, Novelli, A, Battai, N, Piga, N, Mallet, F, Cusack, S. | Deposit date: | 2000-08-21 | Release date: | 2000-11-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mutual Conformational Adaptations in Antigen and Antibody Upon Complex Formation between an Fab and HIV-1 Capsid Protein P24 Structure, 8, 2000
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8AZA
| Structure of RIP2K dimer bound to the XIAP BIR2 domain | Descriptor: | E3 ubiquitin-protein ligase XIAP, Receptor-interacting serine/threonine-protein kinase 2, ZINC ION | Authors: | Pellegrini, E, Cusack, S. | Deposit date: | 2022-09-05 | Release date: | 2022-10-26 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface. Life Sci Alliance, 6, 2023
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7PQK
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1H2T
| Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG | Descriptor: | 20 KDA NUCLEAR CAP BINDING PROTEIN, 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, 80 KDA NUCLEAR CAP BINDING PROTEIN, ... | Authors: | Mazza, C, Segref, A, Mattaj, I.W, Cusack, S. | Deposit date: | 2002-08-16 | Release date: | 2002-10-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Large-Scale Induced Fit Recognition of an M(7)Gpppg CAP Analogue by the Human Nuclear CAP-Binding Complex Embo J., 21, 2002
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1H2U
| Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG | Descriptor: | 20 KDA NUCLEAR CAP BINDING PROTEIN, 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, 80 KDA NUCLEAR CAP BINDING PROTEIN, ... | Authors: | Mazza, C, Segref, A, Mattaj, I.W, Cusack, S. | Deposit date: | 2002-08-16 | Release date: | 2002-10-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Large-Scale Induced Fit Recognition of an M(7)Gpppg CAP Analogue by the Human Nuclear CAP-Binding Complex Embo J., 21, 2002
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8PTJ
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8PSQ
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8PSX
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8PSS
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8PT6
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8PSO
| Tilapia Lake Virus polymerase in vRNA initiation state (core only) | Descriptor: | 5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ... | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2023-07-13 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
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8PT2
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8PSN
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8PSU
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8PTH
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8PT7
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1JID
| Human SRP19 in complex with helix 6 of Human SRP RNA | Descriptor: | HELIX 6 OF HUMAN SRP RNA, MAGNESIUM ION, SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN | Authors: | Wild, K, Sinning, I, Cusack, S. | Deposit date: | 2001-07-02 | Release date: | 2001-10-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of an early protein-RNA assembly complex of the signal recognition particle. Science, 294, 2001
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8PSZ
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8PMP
| Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | Authors: | Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. | Deposit date: | 2023-06-29 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
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8PNT
| Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | Authors: | Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. | Deposit date: | 2023-07-01 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
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8QZ8
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1J1U
| Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(Tyr) and L-tyrosine | Descriptor: | MAGNESIUM ION, TYROSINE, Tyrosyl-tRNA synthetase, ... | Authors: | Kobayashi, T, Nureki, O, Ishitani, R, Tukalo, M, Cusack, S, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-12-17 | Release date: | 2003-06-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion NAT.STRUCT.BIOL., 10, 2003
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1QHV
| HUMAN ADENOVIRUS SEROTYPE 2 FIBRE HEAD | Descriptor: | PROTEIN (ADENOVIRUS FIBRE), SULFATE ION | Authors: | Van Raaij, M.J, Louis, N, Chroboczek, J, Cusack, S. | Deposit date: | 1999-05-28 | Release date: | 1999-09-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structure of the human adenovirus serotype 2 fiber head domain at 1.5 A resolution. Virology, 262, 1999
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