6JJ3
 
 | | BRD4 in complex with 138A | | Descriptor: | 2-methoxy-N-[2-methyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]benzenesulfonamide, Bromodomain-containing protein 4 | | Authors: | Xu, J, Chen, Y, Jiang, F, Zhu, J. | | Deposit date: | 2019-02-25 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.718 Å) | | Cite: | Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis.
J.Med.Chem., 62, 2019
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6JJB
 | | BRD4 in complex with ZZM1 | | Descriptor: | 2-methoxy-N-(1-methyl-2-oxidanylidene-benzo[cd]indol-6-yl)benzenesulfonamide, Bromodomain-containing protein 4 | | Authors: | Xu, J, Chen, Y, Jiang, F, Zhu, J. | | Deposit date: | 2019-02-25 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.508 Å) | | Cite: | Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis.
J.Med.Chem., 62, 2019
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7M12
 | | TVV2 capsid protein | | Descriptor: | Capsid protein | | Authors: | Zhou, H.Z, Stevens, A.W, Cui, Y.X, Muratore, K.A, Johnson, P.J. | | Deposit date: | 2021-03-12 | | Release date: | 2021-04-07 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Atomic Structure of the Trichomonas vaginalis Double-Stranded RNA Virus 2.
Mbio, 12, 2021
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7LWY
 | | TVV viral capsid protein | | Descriptor: | Capsid protein | | Authors: | Zhou, Z.H, Stevens, A.W, Cui, Y.X, Johnson, P.J, Muratore, K.A. | | Deposit date: | 2021-03-02 | | Release date: | 2021-04-07 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Atomic Structure of the Trichomonas vaginalis Double-Stranded RNA Virus 2.
Mbio, 12, 2021
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8EBT
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8EBS
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8EBW
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8EBV
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8EBX
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8EBY
 | | XPC release from Core7-XPA-DNA (AP) | | Descriptor: | DNA, DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, ... | | Authors: | Kim, J, Yang, W. | | Deposit date: | 2022-08-31 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
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8EBU
 | | XPC release from Core7-XPA-DNA (Cy5) | | Descriptor: | DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ... | | Authors: | Kim, J, Yang, W. | | Deposit date: | 2022-08-31 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-17 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
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8FJL
 | | Golden Shiner Reovirus Core Tropical Vertex | | Descriptor: | Clamp protein VP6, Major inner capsid protein VP3, Microtubule-associated protein VP5, ... | | Authors: | Stevens, A.S, Zhou, Z.H. | | Deposit date: | 2022-12-19 | | Release date: | 2023-03-08 | | Last modified: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation.
Protein Cell, 14, 2023
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8FJK
 | | Golden Shiner Reovirus Core Polar Vertex | | Descriptor: | Clamp protein VP6, Major inner capsid protein VP3, Microtubule-associated protein VP5, ... | | Authors: | Stevens, A.S, Zhou, Z.H. | | Deposit date: | 2022-12-19 | | Release date: | 2023-03-22 | | Last modified: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation.
Protein Cell, 14, 2023
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6A73
 | | Complex structure of CSN2 with IP6 | | Descriptor: | COP9 signalosome complex subunit 2,Endolysin, INOSITOL HEXAKISPHOSPHATE, SULFATE ION | | Authors: | Liu, L, Li, D, Rao, F, Wang, T. | | Deposit date: | 2018-07-02 | | Release date: | 2019-07-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.447 Å) | | Cite: | Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5YYF
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7XJG
 | | Cryo-EM structure of E.coli retron-Ec86 in complex with its effector at 2.5 angstrom | | Descriptor: | DNA (105-MER), MAGNESIUM ION, RNA (14-MER), ... | | Authors: | Wang, Y.J, Guan, Z.Y, Zou, T.T. | | Deposit date: | 2022-04-17 | | Release date: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Cryo-EM structures of Escherichia coli Ec86 retron complexes reveal architecture and defence mechanism.
Nat Microbiol, 7, 2022
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7CU8
 | | Crystal structure of the soluble domain of TiME protein from Mycobacterium tuberculosis | | Descriptor: | SULFATE ION, Tube-forming protein in Mycobacterial Envelope (TiME) | | Authors: | Gong, W, Cai, X, Liu, L, Wen, C. | | Deposit date: | 2020-08-21 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Identification and architecture of a putative secretion tube across mycobacterial outer envelope.
Sci Adv, 7, 2021
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7CU9
 | | Crystal structure of the soluble domain of TiME protein from Mycobacterium smegmatis | | Descriptor: | GLYCEROL, MAGNESIUM ION, Tube-forming protein in Mycobacterial Envelpe, ... | | Authors: | Gong, W, Cai, X, Liu, L, Wen, C. | | Deposit date: | 2020-08-21 | | Release date: | 2021-08-25 | | Last modified: | 2022-03-16 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Identification and architecture of a putative secretion tube across mycobacterial outer envelope.
Sci Adv, 7, 2021
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5XEA
 | | Structure of Thogoto virus envelope glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... | | Authors: | Peng, R, Shi, Y, Qi, J, Gao, G.F. | | Deposit date: | 2017-04-03 | | Release date: | 2017-10-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.093 Å) | | Cite: | Structures of human-infecting Thogotovirus fusogens support a common ancestor with insect baculovirus
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6N7W
 | | Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes) | | Descriptor: | DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ... | | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | | Deposit date: | 2018-11-28 | | Release date: | 2019-03-06 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N9V
 | | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1) | | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N9U
 | | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1) | | Descriptor: | DNA (44-MER), DNA primase/helicase, DNA-directed DNA polymerase, ... | | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N9X
 | | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3) | | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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7BPC
 | | Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from Fusarium oxysporum in complex with 2,5-DHBA | | Descriptor: | 2,3-dihydroxybenzoate decarboxylase, 2,5-dihydroxybenzoic acid, ZINC ION | | Authors: | Song, M.K, Feng, J.H, Liu, W.D, Wu, Q.Q, Zhu, D.M. | | Deposit date: | 2020-03-22 | | Release date: | 2020-07-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | 2,3-Dihydroxybenzoic Acid Decarboxylase from Fusarium oxysporum: Crystal Structures and Substrate Recognition Mechanism.
Chembiochem, 21, 2020
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7BP1
 | | Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from Fusarium oxysporum in complex with Catechol | | Descriptor: | 2,3-dihydroxybenzoate decarboxylase, CATECHOL, ZINC ION | | Authors: | Song, M.K, Feng, J.H, Liu, W.D, Wu, Q.Q, Zhu, D.M. | | Deposit date: | 2020-03-21 | | Release date: | 2020-07-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | 2,3-Dihydroxybenzoic Acid Decarboxylase from Fusarium oxysporum: Crystal Structures and Substrate Recognition Mechanism.
Chembiochem, 21, 2020
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