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6UEA
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BU of 6uea by Molmil
Structure of pentameric sIgA complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
登録日2019-09-20
公開日2020-02-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6UE8
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BU of 6ue8 by Molmil
Structure of tetrameric sIgA complex (Class 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
登録日2019-09-20
公開日2020-02-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6UE9
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BU of 6ue9 by Molmil
Structure of tetrameric sIgA complex (Class 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
登録日2019-09-20
公開日2020-02-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6UPH
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BU of 6uph by Molmil
Structure of a Yeast Centromeric Nucleosome at 2.7 Angstrom resolution
分子名称: DNA (119-MER), Histone H2A, Histone H2B.1, ...
著者Migl, D, Kschonsak, M, Arthur, C.P, Khin, Y, Harrison, S.C, Ciferri, C, Dimitrova, Y.N.
登録日2019-10-17
公開日2019-11-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryoelectron Microscopy Structure of a Yeast Centromeric Nucleosome at 2.7 angstrom Resolution.
Structure, 28, 2020
4XHJ
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BU of 4xhj by Molmil
gHgL of Varicella-zoster virus in complex with human neutralizing antibodies.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, ...
著者Xing, Y.
登録日2015-01-05
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.156 Å)
主引用文献A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XI5
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BU of 4xi5 by Molmil
gHgL of varicella-zoster virus in complex with human neutralizing antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
著者Xing, Y.
登録日2015-01-06
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL.
Proc.Natl.Acad.Sci.USA, 112, 2015
6VJA
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BU of 6vja by Molmil
Structure of CD20 in complex with rituximab Fab
分子名称: B-lymphocyte antigen CD20, CHOLESTEROL HEMISUCCINATE, Rituximab Fab heavy chain, ...
著者Rohou, A, Croll, T.I.
登録日2020-01-15
公開日2020-02-26
最終更新日2020-03-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab.
Science, 367, 2020
6WJ5
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BU of 6wj5 by Molmil
Structure of human TRPA1 in complex with inhibitor GDC-0334
分子名称: (4R,5S)-4-fluoro-1-[(4-fluorophenyl)sulfonyl]-5-methyl-N-({5-(trifluoromethyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]pyridin-4-yl}methyl)-L-prolinamide, Transient receptor potential cation channel subfamily A member 1
著者Rohou, A, Rouge, L, Arthur, C.P, Volgraf, M, Chen, H.
登録日2020-04-11
公開日2021-02-17
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
J.Exp.Med., 218, 2021
6VVU
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BU of 6vvu by Molmil
Anti-Tryptase fab E104.v1 bound to tryptase
分子名称: CALCIUM ION, Fab E104.v1 heavy chain, Fab E104.v1 light chain, ...
著者Ultsch, M, Koerber, J.T.
登録日2020-02-18
公開日2020-12-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bivalent antibody pliers inhibit beta-tryptase by an allosteric mechanism dependent on the IgG hinge.
Nat Commun, 11, 2020
6N4I
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BU of 6n4i by Molmil
Structural basis of Nav1.7 inhibition by a gating-modifier spider toxin
分子名称: Beta/omega-theraphotoxin-Tp2a, Nav1.7 VSD2-NavAb channel chimera protein, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
著者Xu, H, Koth, C.M, Payandeh, J.
登録日2018-11-19
公開日2019-01-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.541 Å)
主引用文献Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
Cell, 176, 2019
5UIY
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BU of 5uiy by Molmil
Structure of Bromodomain from human BAZ1A
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bromodomain adjacent to zinc finger domain protein 1A
著者Oppikofer, M, Sudhamsu, J.
登録日2017-01-16
公開日2017-07-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.687 Å)
主引用文献Non-canonical reader modules of BAZ1A promote recovery from DNA damage.
Nat Commun, 8, 2017
8ETR
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BU of 8etr by Molmil
CryoEM Structure of NLRP3 NACHT domain in complex with G2394
分子名称: (6S,8R)-N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Murray, J.M, Johnson, M.C.
登録日2022-10-17
公開日2022-11-02
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Overcoming Preclinical Safety Obstacles to Discover ( S )- N -((1,2,3,5,6,7-Hexahydro- s -indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5 H -pyrazolo[5,1- b ][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.
J.Med.Chem., 65, 2022
6NT4
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BU of 6nt4 by Molmil
Cryo-EM structure of a human-cockroach hybrid Nav channel bound to alpha-scorpion toxin AaH2.
分子名称: (7E,21R,24S)-27-amino-24-hydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaheptacos-7-en-21-yl (9Z,12E)-octadeca-9,12-dienoate, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Clairfeuille, T, Rohou, A, Payandeh, J.
登録日2019-01-28
公開日2019-02-20
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of alpha-scorpion toxin action on Na v channels.
Science, 363, 2019
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