1J97
 
 | | Phospho-Aspartyl Intermediate Analogue of Phosphoserine phosphatase | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Phosphoserine Phosphatase | | 著者 | Cho, H, Wang, W, Kim, R, Yokota, H, Damo, S, Kim, S.-H, Wemmer, D, Kustu, S, Yan, D, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2001-05-24 | | 公開日 | 2001-07-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase.
Proc.Natl.Acad.Sci.USA, 98, 2001
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6JJL
 | | Crystal structure of the DegP dodecamer with a modulator | | 分子名称: | CYS-TYR-ARG-LYS-LEU, Periplasmic serine endoprotease DegP | | 著者 | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | 登録日 | 2019-02-26 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy.
Commun Biol, 3, 2020
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6JJK
 | | Crystal structure of the DegP dodecamer with a modulator | | 分子名称: | CYS-TYR-TYR-LYS-ILE, Periplasmic serine endoprotease DegP | | 著者 | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | 登録日 | 2019-02-26 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
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6JJO
 | | Crystal structure of the DegP dodecamer with a modulator | | 分子名称: | Periplasmic serine endoprotease DegP, TMB-CYRKL modulator | | 著者 | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | 登録日 | 2019-02-26 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.157 Å) | | 主引用文献 | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
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3HSF
 | | HEAT SHOCK TRANSCRIPTION FACTOR (HSF) | | 分子名称: | HEAT SHOCK TRANSCRIPTION FACTOR | | 著者 | Damberger, F.F, Pelton, J.G, Liu, C, Cho, H, Harrison, C.J, Nelson, H.C.M, Wemmer, D.E. | | 登録日 | 1995-08-07 | | 公開日 | 1995-11-14 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined solution structure and dynamics of the DNA-binding domain of the heat shock factor from Kluyveromyces lactis.
J.Mol.Biol., 254, 1995
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1NP3
 | | Crystal structure of class I acetohydroxy acid isomeroreductase from Pseudomonas aeruginosa | | 分子名称: | Ketol-acid reductoisomerase | | 著者 | Ahn, H.J, Eom, S.J, Yoon, H.-J, Lee, B.I, Cho, H, Suh, S.W. | | 登録日 | 2003-01-17 | | 公開日 | 2003-05-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Class I Acetohydroxy Acid Isomeroreductase from Pseudomonas aeruginosa
J.Mol.Biol., 328, 2003
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1BTO
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7LQ7
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 heavy chain, COVA1-16 light chain, ... | | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | | 登録日 | 2021-02-13 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.
Sci Transl Med, 13, 2021
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3BTO
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5ZXB
 | | Crystal structure of ACK1 with compound 10d | | 分子名称: | Activated CDC42 kinase 1, N-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide | | 著者 | Hong, E.M, Kim, H.L, Sim, T.B. | | 登録日 | 2018-05-18 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.
J. Med. Chem., 61, 2018
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5UFP
 | | Crystal structure of PT2399 bound to HIF2a-B*:ARNT-B* complex | | 分子名称: | 3-({(1S)-7-[(difluoromethyl)sulfonyl]-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl}oxy)-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | | 著者 | Du, X. | | 登録日 | 2017-01-05 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | On-target efficacy of a HIF-2 alpha antagonist in preclinical kidney cancer models.
Nature, 539, 2016
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6D0Y
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4UIP
 | | The complex structure of extracellular domain of EGFR with Repebody (rAC1). | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ... | | 著者 | Kang, Y.J, Cha, Y.J, Cho, H.S, Lee, J.J, Kim, H.S. | | 登録日 | 2015-03-31 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy.
Angew.Chem.Int.Ed.Engl., 54, 2015
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7MYZ
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5G28
 | | The crystal structure of light-driven chloride pump ClR at pH 6.0. | | 分子名称: | CHLORIDE ION, CHLORIDE PUMPING RHODOPSIN, OLEIC ACID, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-04-07 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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5G2D
 | | The crystal structure of light-driven chloride pump ClR (T102N) mutant at pH 4.5. | | 分子名称: | CHLORIDE ION, CHLORIDE PUMP RHODOPSIN, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-04-07 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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5G2A
 | | The crystal structure of light-driven chloride pump ClR at pH 6.0 with Bromide ion. | | 分子名称: | BROMIDE ION, CHLORIDE PUMPING RHODOPSIN, RETINAL | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-04-07 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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5G54
 | | The crystal structure of light-driven chloride pump ClR at pH 4.5 | | 分子名称: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-05-19 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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5G2C
 | | The crystal structure of light-driven chloride pump ClR (T102D) mutant at pH 4.5. | | 分子名称: | CHLORIDE ION, CHLORIDE PUMPING RHODOPSIN, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-04-07 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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4ZG0
 | | Crystal structure of Mouse Syndesmos protein | | 分子名称: | Protein syndesmos | | 著者 | Lee, I, Kim, H, Yoo, J, Cho, H, Lee, W. | | 登録日 | 2015-04-22 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan
Biochem.Biophys.Res.Commun., 463, 2015
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7EP6
 | | Engineered Hepatitis B virus core antigen T=4 | | 分子名称: | Capsid protein,Immunoglobulin G-binding protein A | | 著者 | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | 登録日 | 2021-04-26 | | 公開日 | 2021-09-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7EOY
 | | Engineered Hepatitis B virus core antigen T=3 | | 分子名称: | Capsid protein,Immunoglobulin G-binding protein A | | 著者 | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | 登録日 | 2021-04-24 | | 公開日 | 2021-09-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7FDJ
 | | Engineered Hepatitis B virus core antigen with short linker T=4 | | 分子名称: | Capsid protein,Immunoglobulin G-binding protein A | | 著者 | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | 登録日 | 2021-07-16 | | 公開日 | 2021-09-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7XFP
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6V7F
 | | Human Arginase1 Complexed with Bicyclic Inhibitor Compound 13 | | 分子名称: | Arginase-1, MANGANESE (II) ION, {3-[(5R,7S,8S)-8-azaniumyl-8-carboxy-2-azaspiro[4.4]nonan-2-ium-7-yl]propyl}(trihydroxy)borate(1-) | | 著者 | Palte, R.L, Lesburg, C.A. | | 登録日 | 2019-12-08 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.
Acs Med.Chem.Lett., 11, 2020
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