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6O1K
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BU of 6o1k by Molmil
Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:2:2 complex (core complex)
分子名称: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq
著者Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F.
登録日2019-02-20
公開日2019-03-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Architectural principles for Hfq/Crc-mediated regulation of gene expression
Elife, 8, 2019
6O1M
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BU of 6o1m by Molmil
Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex
分子名称: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq
著者Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F.
登録日2019-02-20
公開日2019-03-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Elife, 8, 2019
7DRI
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BU of 7dri by Molmil
Structure of SspE_CTD_41658
分子名称: DUF1524 domain
著者Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G.
登録日2020-12-28
公開日2022-06-29
最終更新日2023-01-11
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE.
Nat Commun, 13, 2022
7DRR
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BU of 7drr by Molmil
Structure of SspE-R100A protein
分子名称: SspE protein
著者Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G.
登録日2020-12-29
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE.
Nat Commun, 13, 2022
7DRS
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BU of 7drs by Molmil
Structure of SspE_40224
分子名称: SspE protein
著者Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G.
登録日2020-12-29
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE.
Nat Commun, 13, 2022
7DK2
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BU of 7dk2 by Molmil
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW07 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MW07 heavy chain, MW07 light chain, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M, Chen, S.
登録日2020-11-22
公開日2021-12-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Architectural versatility of spike neutralization by a SARS-CoV-2 antibody
To Be Published
5XUK
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BU of 5xuk by Molmil
Crystal structure of Helicobacter pylori holo-[acyl-carrier-protein] synthase (AcpS) in complex with coenzyme A
分子名称: COENZYME A, Holo-[acyl-carrier-protein] synthase
著者Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
登録日2017-06-23
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
5XU7
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BU of 5xu7 by Molmil
Crystal structure of Escherichia coli holo-[acyl-carrier-protein] synthase (AcpS)
分子名称: CHLORIDE ION, GLYCEROL, Holo-[acyl-carrier-protein] synthase
著者Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
登録日2017-06-22
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
5XUH
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BU of 5xuh by Molmil
Crystal structure of Escherichia coli holo-[acyl-carrier-protein] synthase (AcpS) D9A mutant in complex with CoA
分子名称: CHLORIDE ION, COENZYME A, GLYCEROL, ...
著者Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
登録日2017-06-23
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
5XUM
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BU of 5xum by Molmil
Crystal structure of Thermotoga maritima holo-[acyl-carrier-protein] synthase (AcpS)
分子名称: GLYCEROL, Holo-[acyl-carrier-protein] synthase
著者Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
登録日2017-06-23
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
5X87
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BU of 5x87 by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation L177T
分子名称: Bestrophin, ZINC ION
著者Zhang, Y, Chen, S, Yang, T.
登録日2017-03-01
公開日2017-11-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca2+-dependent Cl-currents in human RPE.
Elife, 6, 2017
5ZB7
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BU of 5zb7 by Molmil
CTX-M-64 apoenzyme
分子名称: Beta-lactamase
著者Cheng, Q, Chen, S.
登録日2018-02-10
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution.
Acs Infect Dis., 6, 2020
7DT1
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BU of 7dt1 by Molmil
The structure of Lactobacillus fermentum 4,6-alpha-Glucanotransferase
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Yang, W.K, Yong, Y.H, Wu, L, Chen, S, Zhou, J.H, Wu, J.
登録日2021-01-04
公開日2022-01-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.43002272 Å)
主引用文献Characterization of a new 4,6-alpha-glucanotransferase from Limosilactobacillus fermentum NCC 3057 with ability of synthesizing low molecular mass isomalto-/maltopolysaccharide
Food Biosci, 46, 2022
7ENS
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BU of 7ens by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Indolmycin and ATP
分子名称: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-04-19
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENT
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BU of 7ent by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-13 and ATP
分子名称: (5S)-2-(methylamino)-5-[(1R)-1-(4-methyl-1H-indol-3-yl)ethyl]-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-04-19
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ELT
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BU of 7elt by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Trp-AMP
分子名称: TRYPTOPHANYL-5'AMP, Tryptophan--tRNA ligase
著者Xu, M, Chen, S.
登録日2021-04-12
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EL8
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BU of 7el8 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase
分子名称: Tryptophan--tRNA ligase
著者Xu, M, Chen, S.
登録日2021-04-09
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EPV
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BU of 7epv by Molmil
Crystal structure of tigecycline degrading monooxygenase Tet(X4)
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase, GLYCEROL
著者Cheng, Q, Chen, S.
登録日2021-04-27
公開日2021-11-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline.
Bmc Biol., 19, 2021
7EPW
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BU of 7epw by Molmil
Crystal structure of monooxygenase Tet(X4) with tigecycline
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase, TIGECYCLINE
著者Cheng, Q, Chen, S.
登録日2021-04-28
公開日2021-11-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline.
Bmc Biol., 19, 2021
7EV3
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BU of 7ev3 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-10 and ATP
分子名称: (5S)-5-[(1R)-1-(4-fluoranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-05-20
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EV2
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BU of 7ev2 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-11 and ATP
分子名称: (5S)-5-[(1R)-1-(4-chloranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-05-20
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
5V2N
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BU of 5v2n by Molmil
Crystal Structure of APO Human SETD8
分子名称: 1,2-ETHANEDIOL, N-lysine methyltransferase KMT5A
著者Skene, R.J.
登録日2017-03-05
公開日2018-03-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The dynamic conformational landscape of the protein methyltransferase SETD8.
Elife, 8, 2019
1F5T
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BU of 1f5t by Molmil
DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE
分子名称: 43MER DNA CONTAINING DXTR CONSENSUS BINDING SEQUENCE, DIPHTHERIA TOXIN REPRESSOR, NICKEL (II) ION
著者Chen, S, White, A, Love, J, Murphy, J.R, Ringe, D.
登録日2000-06-15
公開日2000-09-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Methyl groups of thymine bases are important for nucleic acid recognition by DtxR.
Biochemistry, 39, 2000
8K89
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BU of 8k89 by Molmil
Crystal structure of NFIL3
分子名称: Nuclear factor interleukin-3-regulated protein
著者Min, J.R, Chen, S.Z, Liu, K.
登録日2023-07-29
公開日2024-03-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
J.Biol.Chem., 300, 2024
8K8D
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BU of 8k8d by Molmil
Crystal structure of C/EBPbeta BZIP domain bound to a high affinity DNA
分子名称: CCAAT/enhancer-binding protein beta, DNA (5'-D(*CP*AP*TP*TP*AP*CP*GP*TP*AP*AP*TP*G)-3')
著者Min, J.R, Chen, S.Z, Liu, K.
登録日2023-07-29
公開日2024-03-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
J.Biol.Chem., 300, 2024

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