6L9J
| Structure of yeast Snf5 and Swi3 subcomplex | 分子名称: | GLYCEROL, SWI/SNF chromatin-remodeling complex subunit SNF5, SWI/SNF complex subunit SWI3 | 著者 | Long, J, Zhou, H. | 登録日 | 2019-11-10 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.642 Å) | 主引用文献 | Snf5 and Swi3 subcomplex formation is required for SWI/SNF complex function in yeast. Biochem.Biophys.Res.Commun., 526, 2020
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5ZH6
| Crystal structure of Parvalbumin SPV-II of Mustelus griseus | 分子名称: | CALCIUM ION, Parvalbumin SPV-II, SULFATE ION | 著者 | Yang, R.Q, Chen, Y.L, Jin, T.C, Cao, M.J. | 登録日 | 2018-03-11 | 公開日 | 2018-08-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Purification, Characterization, and Crystal Structure of Parvalbumins, the Major Allergens in Mustelus griseus. J. Agric. Food Chem., 66, 2018
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5ZGM
| Crystal Structure of Parvalbumin SPVI, the Major Allergens in Mustelus griseus | 分子名称: | CALCIUM ION, Parvalbumin SPVI, SULFATE ION | 著者 | Yang, R.Q, Chen, Y.L, Jin, T.C, Cao, M.J. | 登録日 | 2018-03-09 | 公開日 | 2018-08-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Purification, Characterization, and Crystal Structure of Parvalbumins, the Major Allergens in Mustelus griseus. J. Agric. Food Chem., 66, 2018
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3B5I
| Crystal structure of Indole-3-acetic Acid Methyltransferase | 分子名称: | MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase-like protein | 著者 | Ferrer, J.-L, Noel, J.P. | 登録日 | 2007-10-26 | 公開日 | 2008-01-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural, Biochemical, and Phylogenetic Analyses Suggest That Indole-3-Acetic Acid Methyltransferase Is an Evolutionarily Ancient Member of the SABATH Family. Plant Physiol., 146, 2008
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5X02
| Crystal structure of the FLT3 kinase domain bound to the inhibitor FF-10101 | 分子名称: | N-[(2S)-1-[5-[2-[(4-cyanophenyl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxidanylidene-propan-2-yl]-4-(dimethylamino)-N-methyl-but-2-enamide, Receptor-type tyrosine-protein kinase FLT3, SULFATE ION | 著者 | Fujikawa, N, Hirano, D, Takasaki, M, Terada, D, Hagiwara, S, Park, S.-Y, Sugiyama, K. | 登録日 | 2017-01-19 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells withFLT3mutations. Blood, 131, 2018
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8INP
| A reversible glycosyltransferase of tectorigenin - Bc7OUGT | 分子名称: | Bc7OUGT, URIDINE-5'-DIPHOSPHATE, beta-D-glucopyranose | 著者 | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | 登録日 | 2023-03-10 | 公開日 | 2023-08-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence. Plant Biotechnol J, 21, 2023
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8ITA
| A reversible glycosyltransferase of tectorigenin - Bc7OUGT complexed with UDP and tectorigenin | 分子名称: | 3-(4-hydroxyphenyl)-6-methoxy-5,7-bis(oxidanyl)chromen-4-one, Bc7OUGT, URIDINE-5'-DIPHOSPHATE | 著者 | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | 登録日 | 2023-03-22 | 公開日 | 2023-08-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence. Plant Biotechnol J, 21, 2023
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4ZRP
| TC:CD320 | 分子名称: | CALCIUM ION, CD320 antigen, CYANOCOBALAMIN, ... | 著者 | Alam, A, Locher, K.P. | 登録日 | 2015-05-12 | 公開日 | 2016-07-20 | 最終更新日 | 2021-08-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of transcobalamin recognition by human CD320 receptor. Nat Commun, 7, 2016
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4ZRQ
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7DV4
| Crystal structure of anti-CTLA-4 VH domain in complex with human CTLA-4 | 分子名称: | 1,2-ETHANEDIOL, 4003-1(VH), Cytotoxic T-lymphocyte protein 4 | 著者 | Li, H, Gan, X, He, Y. | 登録日 | 2021-01-12 | 公開日 | 2022-01-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | An anti-CTLA-4 heavy chain-only antibody with enhanced T reg depletion shows excellent preclinical efficacy and safety profile. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YCX
| The structure of INTAC-PEC complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | 登録日 | 2022-07-02 | 公開日 | 2023-03-15 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
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2KOU
| DICER LIKE protein | 分子名称: | Dicer-like protein 4 | 著者 | Qin, H, Song, J, Yuan, Y.A. | 登録日 | 2009-09-30 | 公開日 | 2010-02-16 | 最終更新日 | 2021-11-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Arabidopsis thaliana DCL4 DUF283 domain reveals a noncanonical double-stranded RNA-binding fold for protein-protein interaction Rna, 2010
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6J72
| Crystal structure of IniA from Mycobacterium smegmatis with GTP bound | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Isoniazid inducible gene protein IniA, L(+)-TARTARIC ACID, ... | 著者 | Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H. | 登録日 | 2019-01-16 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mycobacterial dynamin-like protein IniA mediates membrane fission. Nat Commun, 10, 2019
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6J73
| Crystal structure of IniA from Mycobacterium smegmatis | 分子名称: | Isoniazid inducible gene protein IniA | 著者 | Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H. | 登録日 | 2019-01-16 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.211 Å) | 主引用文献 | Mycobacterial dynamin-like protein IniA mediates membrane fission. Nat Commun, 10, 2019
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5IT3
| Swirm domain of human Lsd1 | 分子名称: | Lysine-specific histone demethylase 1A, MAGNESIUM ION | 著者 | Jeffrey, P.D, Yuan, P. | 登録日 | 2016-03-16 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A Tlx-interacting peptide of Lsd1 inhibits the proliferation of brain tumor stem cells To Be Published
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4QBA
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4RBW
| Crystal structure of human alpha-defensin 5, HD5 (Thr7Arg Glu21Arg mutant) | 分子名称: | CHLORIDE ION, Defensin-5, SULFATE ION | 著者 | Pazgier, M, Gohain, N, Tolbert, W.D. | 登録日 | 2014-09-13 | 公開日 | 2015-07-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Design of a potent antibiotic peptide based on the active region of human defensin 5. J.Med.Chem., 58, 2015
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4RBX
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2NSQ
| Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-06 | 公開日 | 2006-12-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein To be Published
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7UYD
| Inhibitor bound VIM1 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Metallo-beta-lactamase VIM-2-like protein, ... | 著者 | Fischmann, T.O, Scapin, G. | 登録日 | 2022-05-06 | 公開日 | 2023-05-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Structure Guided Discovery of Novel Pan Metallo-beta-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration. J.Med.Chem., 67, 2024
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7UYA
| Inhibitor bound VIM1 | 分子名称: | (2M)-4'-(piperidin-4-yl)-2-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-sulfonamide, Beta-lactamase VIM-1, ZINC ION | 著者 | Fischmann, T.O, Scapin, G. | 登録日 | 2022-05-06 | 公開日 | 2023-05-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | 主引用文献 | Structure Guided Discovery of Novel Pan Metallo-beta-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration. J.Med.Chem., 67, 2024
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7UYC
| Inhibitor bound VIM1 | 分子名称: | (2P)-4'-(piperidin-4-yl)-4-[(piperidin-4-yl)methyl]-2-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-sulfonamide, Beta-lactamase VIM-1, MAGNESIUM ION, ... | 著者 | Fischmann, T.O, Scapin, G. | 登録日 | 2022-05-06 | 公開日 | 2023-05-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | Structure Guided Discovery of Novel Pan Metallo-beta-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration. J.Med.Chem., 67, 2024
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7UYB
| Inhibitor bound VIM1 | 分子名称: | (2M)-4'-(piperidin-4-yl)-2-(1H-tetrazol-5-yl)-4-(trifluoromethyl)[1,1'-biphenyl]-3-sulfonamide, Beta-lactamase VIM-1, ZINC ION | 著者 | Fischmann, T.O, Scapin, G. | 登録日 | 2022-05-06 | 公開日 | 2023-05-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | 主引用文献 | Structure Guided Discovery of Novel Pan Metallo-beta-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration. J.Med.Chem., 67, 2024
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6LQC
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6LQL
| Complex structure of CHAO with product from Erythrobacteraceae bacterium | 分子名称: | 1-[(4-methoxyphenyl)methyl]-3,4,5,6,7,8-hexahydroisoquinoline, Amine oxidase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Huang, Z.D. | 登録日 | 2020-01-14 | 公開日 | 2020-06-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Asymmetric Synthesis of a Key Dextromethorphan Intermediate and Its Analogues Enabled by a New Cyclohexylamine Oxidase: Enzyme Discovery, Reaction Development, and Mechanistic Insight. J.Org.Chem., 85, 2020
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