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7YUX
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BU of 7yux by Molmil
MtaLon-ADP for the spiral oligomers of hexamer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease
Authors:Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
Deposit date:2022-08-18
Release date:2023-10-25
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
6IQQ
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BU of 6iqq by Molmil
Crystal structure of Prc with S452I and L252Y mutations in complex with NlpI
Descriptor: CALCIUM ION, Lipoprotein NlpI, Tail-specific protease
Authors:Chueh, C.K, Chang, C.I.
Deposit date:2018-11-08
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
6IQU
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BU of 6iqu by Molmil
Crystal structure of Prc with PDZ domain deletion in complex with NlpI
Descriptor: Lipoprotein NlpI, Tail-specific protease
Authors:Chueh, C.K, Chang, C.I.
Deposit date:2018-11-08
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
6IQR
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BU of 6iqr by Molmil
Crystal structure of Prc with S452I and L252Y mutations
Descriptor: Tail-specific protease
Authors:Chueh, C.K, Chang, C.I.
Deposit date:2018-11-08
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
6IQS
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BU of 6iqs by Molmil
Crystal structure of Prc with L245A and L340G mutations in complex with NlpI
Descriptor: Lipoprotein NlpI, Tail-specific protease
Authors:Chuech, C.K, Chang, C.I.
Deposit date:2018-11-08
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
7FID
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BU of 7fid by Molmil
Processive cleavage of substrate at individual proteolytic active sites of the Lon proteasecomplex (conformation 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I.
Deposit date:2021-07-31
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
7FIZ
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BU of 7fiz by Molmil
Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 3)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I.
Deposit date:2021-08-01
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
7FIE
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BU of 7fie by Molmil
Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I.
Deposit date:2021-07-31
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
4OM4
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BU of 4om4 by Molmil
Crystal structure of CTX A2 from Taiwan Cobra (Naja naja atra)
Descriptor: Cytotoxin 2
Authors:Lin, C.C, Chang, C.I, Wu, W.G.
Deposit date:2014-01-26
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface.
J.Biol.Chem., 289, 2014
5WQL
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BU of 5wql by Molmil
Structure of a PDZ-protease bound to a substrate-binding adaptor
Descriptor: ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA, LEU-SER-ARG-SER, ...
Authors:Su, M.Y, Chang, C.I.
Deposit date:2016-11-27
Release date:2017-11-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc
Nat Commun, 8, 2017
2M5V
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BU of 2m5v by Molmil
Three-dimensional structure of human NLRP10/PYNOD pyrin domain
Descriptor: NACHT, LRR and PYD domains-containing protein 10
Authors:Su, M.Y, Chang, C.F, Chang, C.I.
Deposit date:2013-03-11
Release date:2013-04-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue.
Plos One, 8, 2013
1LEZ
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BU of 1lez by Molmil
CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS ACTIVATOR MKK3B
Descriptor: MAP kinase kinase 3b, MITOGEN-ACTIVATED PROTEIN KINASE 14
Authors:Chang, C.-I, Xu, B.-E, Akella, R, Cobb, M.H, Goldsmith, E.J.
Deposit date:2002-04-10
Release date:2002-07-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.
Mol.Cell, 9, 2002
1LEW
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BU of 1lew by Molmil
CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS NUCLEAR SUBSTRATE MEF2A
Descriptor: Mitogen-activated protein kinase 14, Myocyte-specific enhancer factor 2A
Authors:Chang, C.-I, Xu, B.-E, Akella, R, Cobb, M.H, Goldsmith, E.J.
Deposit date:2002-04-10
Release date:2002-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.
Mol.Cell, 9, 2002
6WQH
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BU of 6wqh by Molmil
Molecular basis for the ATPase-powered substrate translocation by the Lon AAA+ protease
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Ig2 substrate, Lon protease, ...
Authors:Zhang, K, Li, S, Hsiehb, K, Sub, S, Pintilie, G, Chiu, W, Chang, C.
Deposit date:2020-04-28
Release date:2021-06-09
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease.
J.Biol.Chem., 297, 2021
8IKR
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BU of 8ikr by Molmil
Crystal structure of DpaA
Descriptor: YkuD domain-containing protein
Authors:Wang, H.-J, Hsieh, K.-Y, Lee, S.-H, Chang, C.-I.
Deposit date:2023-03-01
Release date:2023-10-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the hydrolytic activity of the transpeptidase-like protein DpaA to detach Braun's lipoprotein from peptidoglycan.
Mbio, 14, 2023
7FD4
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BU of 7fd4 by Molmil
A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ...
Authors:Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C.
Deposit date:2021-07-16
Release date:2021-11-03
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
7FD5
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BU of 7fd5 by Molmil
A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ...
Authors:Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C.
Deposit date:2021-07-16
Release date:2021-11-03
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
4R8F
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BU of 4r8f by Molmil
Crystal structure of yeast aminopeptidase 1 (Ape1)
Descriptor: Vacuolar aminopeptidase 1
Authors:Su, M.-Y, Chang, C.-I.
Deposit date:2014-09-02
Release date:2015-08-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of yeast Ape1 and its role in autophagic vesicle formation.
Autophagy, 11, 2015
7CRA
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BU of 7cra by Molmil
Crystal structure of the N-terminal fragment (residue 1-291) of LonA protease from Meiothermus taiwanensis
Descriptor: Lon protease, SULFATE ION
Authors:Lin, C.-C, Chang, C.-I.
Deposit date:2020-08-13
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular insights into substrate recognition and discrimination by the N-terminal domain of Lon AAA+ protease.
Elife, 10, 2021
7CR9
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BU of 7cr9 by Molmil
Crystal structure of the N-terminal fragment (residue 1-206) of LonA protease from Meiothermus taiwanensis
Descriptor: Lon protease
Authors:Lin, C.-C, Chang, C.-I.
Deposit date:2020-08-12
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:Molecular insights into substrate recognition and discrimination by the N-terminal domain of Lon AAA+ protease.
Elife, 10, 2021
2PN5
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BU of 2pn5 by Molmil
Crystal Structure of TEP1r
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ...
Authors:Baxter, R.H.G.
Deposit date:2007-04-23
Release date:2007-07-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Structural basis for conserved complement factor-like function in the antimalarial protein TEP1
Proc.Natl.Acad.Sci.Usa, 104, 2007
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