4IHX
 
 | |
5W52
 | | MicroED structure of the segment, DLIIKGISVHI, from the RRM2 of TDP-43, residues 247-257 | | Descriptor: | TAR DNA-binding protein 43 | | Authors: | Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | | Deposit date: | 2017-06-13 | | Release date: | 2018-02-21 | | Last modified: | 2024-04-03 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.4 Å) | | Cite: | Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
|
|
5WKD
 | | Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306 | | Descriptor: | TAR DNA-binding protein 43 | | Authors: | Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | | Deposit date: | 2017-07-25 | | Release date: | 2018-04-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
|
|
5WB4
 | | Crystal structure of the TarA wall teichoic acid glycosyltransferase | | Descriptor: | N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, SULFATE ION | | Authors: | Kattke, M.D, Cascio, D, Sawaya, M.R, Clubb, R.T. | | Deposit date: | 2017-06-27 | | Release date: | 2019-01-16 | | Last modified: | 2019-07-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria.
Plos Pathog., 15, 2019
|
|
5WFG
 | | Crystal structure of the TarA wall teichoic acid glycosyltransferase bound to UDP | | Descriptor: | N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, URIDINE-5'-DIPHOSPHATE | | Authors: | Kattke, M.D, Cascio, D, Sawaya, M.R, Clubb, R.T. | | Deposit date: | 2017-07-11 | | Release date: | 2019-01-16 | | Last modified: | 2019-07-31 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria.
Plos Pathog., 15, 2019
|
|
5WKB
 | | MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity domain of TDP-43, residues 312-317 | | Descriptor: | TAR DNA-binding protein 43 | | Authors: | Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | | Deposit date: | 2017-07-24 | | Release date: | 2018-05-23 | | Last modified: | 2024-03-13 | | Method: | ELECTRON CRYSTALLOGRAPHY (1 Å) | | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
|
|
4PBD
 | |
4PCK
 | | Crystal structure of the P22S mutant of N-terminal CS domain of human Shq1 | | Descriptor: | GLYCEROL, Protein SHQ1 homolog | | Authors: | Singh, M, Wang, Z, Cascio, D, Feigon, J. | | Deposit date: | 2014-04-15 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.401 Å) | | Cite: | Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
|
|
3IDW
 | |
3UID
 | | Crystal Structure of Protein Ms6760 from Mycobacterium smegmatis | | Descriptor: | Putative uncharacterized protein | | Authors: | Bajaj, R.A, Miallau, L, Cascio, D, Arbing, M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2011-11-04 | | Release date: | 2011-11-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.571 Å) | | Cite: | Crystal structure of the toxin Msmeg_6760, the structural homolog of Mycobacterium tuberculosis Rv2035, a novel type II toxin involved in the hypoxic response.
Acta Crystallogr F Struct Biol Commun, 72, 2016
|
|
3LE4
 | |
6DGB
 | | Crystal structure of the C-terminal catalytic domain of IS1535 TnpA, an IS607-like serine recombinase | | Descriptor: | IS607 family transposase IS1535 | | Authors: | Chen, W.Y, Hancock, S.P, Cascio, D, Johnson, R.C. | | Deposit date: | 2018-05-17 | | Release date: | 2018-07-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition.
Elife, 7, 2018
|
|
6DCB
 | | Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA | | Descriptor: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | Authors: | Yang, Y, Eichhorn, C, Cascio, D, Feigon, J. | | Deposit date: | 2018-05-04 | | Release date: | 2018-12-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.
Nat. Chem. Biol., 15, 2019
|
|
6DGC
 | | Crystal structure of the C-terminal catalytic domain of ISC1926 TnpA, an IS607-like serine recombinase | | Descriptor: | ISC1926 TnpA C-terminal catalytic domain | | Authors: | Hancock, S.P, Kumar, P, Cascio, D, Johnson, R.C. | | Deposit date: | 2018-05-17 | | Release date: | 2018-07-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition.
Elife, 7, 2018
|
|
6DCC
 | | Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA | | Descriptor: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | Authors: | Yang, Y, Eichhorn, C, Cascio, D, Feigon, J. | | Deposit date: | 2018-05-04 | | Release date: | 2018-12-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.
Nat. Chem. Biol., 15, 2019
|
|
6DKQ
 | | Crystal structure of the Shr Hemoglobin Interacting Domain 2 | | Descriptor: | Heme-binding protein Shr, SULFATE ION | | Authors: | Macdonald, R, Cascio, D, Collazo, M.J, Clubb, R.T. | | Deposit date: | 2018-05-30 | | Release date: | 2018-10-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Streptococcus pyogenes Shr protein captures human hemoglobin using two structurally unique binding domains.
J.Biol.Chem., 293, 2018
|
|
6E73
 | | Structure of Human Transthyretin Val30Met Mutant in Complex with Diflunisal | | Descriptor: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, ACETATE ION, Transthyretin | | Authors: | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | | Deposit date: | 2018-07-25 | | Release date: | 2019-07-31 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.797 Å) | | Cite: | Structural Variants of Transthyretin
to be published
|
|
6EEX
 | | L-GSTSTA from degenerate octameric repeats in InaZ, residues 707-712 | | Descriptor: | L-GSTSTA from ice nucleaction protein, inaZ | | Authors: | Zee, C, Glynn, C, Gallagher-Jones, M, Miao, J, Santiago, C.G, Cascio, D, Gonen, T, Sawaya, M.R, Rodriguez, J.A. | | Deposit date: | 2018-08-15 | | Release date: | 2019-04-03 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Homochiral and racemic MicroED structures of a peptide repeat from the ice-nucleation protein InaZ.
IUCrJ, 6, 2019
|
|
3G5O
 | | The crystal structure of the toxin-antitoxin complex RelBE2 (Rv2865-2866) from Mycobacterium tuberculosis | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | | Authors: | Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2009-02-05 | | Release date: | 2009-04-14 | | Last modified: | 2022-11-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes.
Structure, 21, 2013
|
|
3LSU
 | |
4RC1
 | | Structure of the methanofuran/methanopterin biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii with PRPP | | Descriptor: | PHOSPHATE ION, UPF0264 protein MJ1099 | | Authors: | Bobik, T.A, Morales, E.J, Cascio, D, Sawaya, M.R, Yeates, T.O, Rasche, M.E. | | Deposit date: | 2014-09-14 | | Release date: | 2014-11-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the methanofuran/methanopterin-biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii.
Acta Crystallogr F Struct Biol Commun, 70, 2014
|
|
4TLU
 | |
4TNG
 | |
4TL5
 | | Crystal Structure of Human Transthyretin Ser85Pro Mutant | | Descriptor: | CHLORIDE ION, SODIUM ION, Transthyretin | | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | | Deposit date: | 2014-05-28 | | Release date: | 2015-10-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
|
|
3NGK
 | |
