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2M58
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BU of 2m58 by Molmil
Structure of 2'-5' AG1 lariat forming ribozyme in its inactive state
分子名称: RNA (59-MER)
著者Carlomagno, T, Amata, I, Codutti, L, Falb, M, Fohrer, J, Simon, B.
登録日2013-02-18
公開日2013-04-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme.
J.Am.Chem.Soc., 135, 2013
8AOU
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BU of 8aou by Molmil
Solution NMR structure of full-length Nsp1 from SARS-CoV-2.
分子名称: Host translation inhibitor nsp1
著者Wang, Y, Kirkpatrick, J.P, Carlomagno, T.
登録日2022-08-08
公開日2022-12-28
最終更新日2023-02-15
実験手法SOLUTION NMR
主引用文献Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2.
Structure, 31, 2023
6O22
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BU of 6o22 by Molmil
Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate.
分子名称: Histone H3.2, Histone H4, Histone acetyltransferase RTT109, ...
著者Danilenko, N, Carlomagno, T, Kirkpatrick, J.P.
登録日2019-02-22
公開日2019-07-31
最終更新日2019-08-14
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Histone chaperone exploits intrinsic disorder to switch acetylation specificity.
Nat Commun, 10, 2019
1OJ5
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BU of 1oj5 by Molmil
Crystal structure of the Nco-A1 PAS-B domain bound to the STAT6 transactivation domain LXXLL motif
分子名称: IODIDE ION, SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6, STEROID RECEPTOR COACTIVATOR 1A
著者Razeto, A, Ramakrishnan, V, Giller, K, Lakomek, N, Carlomagno, T, Griesinger, C, Lodrini, M, Litterst, C.M, Pftizner, E, Becker, S.
登録日2003-07-02
公開日2004-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of the Ncoa-1/Src-1 Pas-B Domain Bound to the Lxxll Motif of the Stat6 Transactivation Domain
J.Mol.Biol., 336, 2004
6ZDT
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BU of 6zdt by Molmil
Crystal structure of eukaryotic Fibrillarin with Nop56 N-terminal domain
分子名称: Nucleolar protein 56, rRNA 2'-O-methyltransferase fibrillarin
著者Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W.
登録日2020-06-15
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.
Rna, 27, 2021
6F0Y
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BU of 6f0y by Molmil
Rtt109 peptide bound to Asf1
分子名称: Histone chaperone ASF1, histone acetyltransferase Rtt109 C-terminus
著者Lercher, L, Kirkpatrick, J.P, Carlomagno, T.
登録日2017-11-21
公開日2017-12-27
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献Structural characterization of the Asf1-Rtt109 interaction and its role in histone acetylation.
Nucleic Acids Res., 46, 2018
2KDU
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BU of 2kdu by Molmil
Structural basis of the Munc13-1/Ca2+-Calmodulin interaction: A novel 1-26 calmodulin binding motif with a bipartite binding mode
分子名称: CALCIUM ION, Calmodulin, Protein unc-13 homolog A
著者Rodriguez-Castaneda, F.A, Maestre-Martinez, M, Coudevylle, N, Dimova, K, Jahn, O, Junge, H, Becker, S, Brose, N, Carlomagno, T, Griesinger, C.
登録日2009-01-19
公開日2009-12-15
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity.
Embo J., 29, 2010
5A18
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BU of 5a18 by Molmil
The structure of the SOLE element of oskar mRNA
分子名称: OSKAR MRNA
著者Simon, B, Masiewicz, P, Ephrussi, A, Carlomagno, T.
登録日2015-04-28
公開日2015-05-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Structure of the Sole Element of Oskar Mrna.
RNA, 21, 2015
5A17
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BU of 5a17 by Molmil
The structure of the SOLE element of oskar mRNA
分子名称: OSKAR MRNA
著者Simon, B, Masiewicz, P, Ephrussi, A, Carlomagno, T.
登録日2015-04-28
公開日2015-05-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Structure of the Sole Element of Oskar Mrna.
RNA, 21, 2015
4BD3
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BU of 4bd3 by Molmil
Phf19 links methylated lysine 36 of histone H3 to regulation of Polycomb activity
分子名称: HISTONE H3, PHD FINGER PROTEIN 19
著者Lapinaite, A, Simon, B, Carlomagno, T.
登録日2012-10-04
公開日2012-10-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Phf19 Links Methylated Lys36 of Histone H3 to Regulation of Polycomb Activity
Nat.Struct.Mol.Biol., 19, 2012
4BY9
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BU of 4by9 by Molmil
The structure of the Box CD enzyme reveals regulation of rRNA methylation
分子名称: 5'-R(*UP*CP*GP*CP*CP*CP*AP*UP*CP*AP*CP)-3', 50S RIBOSOMAL PROTEIN L7AE, FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERASE, ...
著者Lapinaite, A, Simon, B, Skjaerven, L, Rakwalska-Bange, M, Gabel, F, Carlomagno, T.
登録日2013-07-18
公開日2013-10-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.
Nature, 502, 2013
2XEB
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BU of 2xeb by Molmil
NMR STRUCTURE OF THE PROTEIN-UNBOUND SPLICEOSOMAL U4 SNRNA 5' STEM LOOP
分子名称: 5'-R(P*GP*AP*UP*CP*GP*UP*AP*GP*CP*CP*AP*AP*UP*GP*AP* GP*GP*UP*U)-3', 5'-R(P*GP*CP*CP*GP*AP*GP*GP*CP*GP*CP*GP*AP*UP*C)-3'
著者Falb, M, Amata, I, Gabel, F, Simon, B, Carlomagno, T.
登録日2010-05-12
公開日2010-05-26
最終更新日2018-01-17
実験手法SOLUTION NMR
主引用文献Structure of the K-turn U4 RNA: a combined NMR and SANS study.
Nucleic Acids Res., 38, 2010
2XFM
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BU of 2xfm by Molmil
Complex structure of the MIWI Paz domain bound to methylated single stranded RNA
分子名称: 5'-R(*AP*CP*CP*GP*AP*CP*UP*(OMU)P)-3', PIWI-LIKE PROTEIN 1
著者Simon, B, Kirkpatrick, J.P, Eckhardt, S, Sehr, P, Andrade-Navarro, M.A, Pillai, R.S, Carlomagno, T.
登録日2010-05-27
公開日2011-01-26
最終更新日2011-10-26
実験手法SOLUTION NMR
主引用文献Recognition of 2'-O-Methylated 3'-End of Pirna by the Paz Domain of a Piwi Protein.
Structure, 19, 2011
7OC3
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BU of 7oc3 by Molmil
Crystal structure of the third tudor domain of Qin
分子名称: PHOSPHATE ION, Qin
著者Dhimole, N, Klug, W, Carlomagno, T.
登録日2021-04-25
公開日2022-05-04
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of the third tudor domain of Qin
To Be Published
7OZQ
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BU of 7ozq by Molmil
Crystal structure of archaeal L7Ae bound to eukaryotic kink-loop
分子名称: 50S ribosomal protein L7Ae, ACETATE ION, CALCIUM ION, ...
著者Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W.
登録日2021-06-28
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Eukaryotic Box C/D methylation machinery has two non-symmetric protein assembly sites.
Sci Rep, 11, 2021
6ROZ
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BU of 6roz by Molmil
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based switch motif
分子名称: Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based switch motif (ITSM)
著者Krausze, J, Sikorska, J, Carlomagno, T.
登録日2019-05-13
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
6ROY
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BU of 6roy by Molmil
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based inhibitory motif
分子名称: Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based inhibitory motif (ITIM)
著者Krausze, J, Sikorska, J, Carlomagno, T.
登録日2019-05-13
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
6TPH
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BU of 6tph by Molmil
Structure of a protein-RNA complex by ssNMR
分子名称: 50S ribosomal protein L7Ae, RNA (26-MER)
著者Mumdooh, A, Marchanka, A, Carlomagno, T.
登録日2019-12-13
公開日2020-02-12
最終更新日2023-06-14
実験手法SOLID-STATE NMR
主引用文献Structure of a Protein-RNA Complex by Solid-State NMR Spectroscopy.
Angew.Chem.Int.Ed.Engl., 59, 2020
2N2P
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BU of 2n2p by Molmil
Solution structure of a double base-pair inversion mutant of murine tumour necrosis factor alpha CDE-23 RNA
分子名称: RNA (5'-R(P*GP*CP*AP*UP*GP*UP*UP*UP*AP*GP*UP*GP*UP*CP*UP*AP*AP*AP*CP*GP*GP*UP*U)-3')
著者Codutti, L, Leppek, K, Zalesak, J, Windeisen, V, Masiewicz, P, Stoecklin, G, Carlomagno, T.
登録日2015-05-11
公開日2015-08-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin.
Structure, 23, 2015
2N2O
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BU of 2n2o by Molmil
Structure of murine tumour necrosis factor alpha CDE RNA
分子名称: RNA (5'-R(P*GP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*UP*U)-3')
著者Codutti, L, Leppek, K, Zalesak, J, Windeisen, V, Masiewicz, P, Stoecklin, G, Carlomagno, T.
登録日2015-05-11
公開日2015-08-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin.
Structure, 23, 2015
2N0R
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BU of 2n0r by Molmil
RNA structure determination by solid-state NMR spectroscopy
分子名称: RNA (5'-R(*GP*CP*UP*GP*AP*GP*CP*UP*CP*GP*AP*AP*AP*GP*AP*GP*CP*AP*AP*UP*GP*AP*UP*GP*UP*C)-3')
著者Marchanka, A, Simon, B, Althoff-Ospelt, G, Carlomagno, T.
登録日2015-03-12
公開日2015-05-20
最終更新日2023-06-14
実験手法SOLID-STATE NMR
主引用文献RNA structure determination by solid-state NMR spectroscopy.
Nat Commun, 6, 2015
7NXE
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BU of 7nxe by Molmil
Structure of the Phospholipase C gamma 1 tSH2 domain in complex with a phosphorylated KSHV pK15 peptide
分子名称: Isoform 2 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, Protein K15
著者Ssebyatika, G, Krey, T.
登録日2021-03-18
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recruitment of phospholipase C gamma 1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation.
Plos Pathog., 17, 2021
4IE9
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BU of 4ie9 by Molmil
Bovine PKA C-alpha in complex with 3-pyridylmethyl-5-methyl-1H-pyrazole-3-carboxylate
分子名称: GLYCEROL, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, ...
著者Dreyer, M.K, Schiffer, A, Lodge, J.
登録日2012-12-13
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring
J.Am.Chem.Soc., 135, 2013
4IJ9
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BU of 4ij9 by Molmil
Bovine PKA C-alpha in complex with 2-[[5-(4-pyridyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-(2-thiophenyl)ethanone
分子名称: 2-[[5-(4-pyridyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-(2-thiophenyl)ethanone, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
著者Dreyer, M.K, Schiffer, A.
登録日2012-12-21
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring
J.Am.Chem.Soc., 135, 2013
6R5G
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BU of 6r5g by Molmil
C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
分子名称: ITSM, Tyrosine-protein phosphatase non-receptor type 11
著者Marasco, M.
登録日2019-03-25
公開日2020-02-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020

 

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