1E1P
 
 | | Human prion protein variant S170N | | Descriptor: | PRION PROTEIN | | Authors: | Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K. | | Deposit date: | 2000-05-09 | | Release date: | 2000-07-20 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR Structures of Three Single-Residue Variants of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
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4UY9
 | | Structure of MLK1 kinase domain with leucine zipper 1 | | Descriptor: | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 | | Authors: | Read, J.A, Brassington, C, Pollard, H.K, Phillips, C, Green, I, Overmann, R, Collier, M. | | Deposit date: | 2014-08-29 | | Release date: | 2015-09-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Recurrent Mlk4 Loss-of-Function Mutations Suppress Jnk Signaling to Promote Colon Tumorigenesis.
Cancer Res., 76, 2016
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1DMT
 | | STRUCTURE OF HUMAN NEUTRAL ENDOPEPTIDASE COMPLEXED WITH PHOSPHORAMIDON | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ... | | Authors: | Oefner, C, D'Arcy, A, Hennig, M, Winkler, F.K, Dale, G.E. | | Deposit date: | 1999-12-15 | | Release date: | 2000-12-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon.
J.Mol.Biol., 296, 2000
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1DN3
 | | NMR STRUCTURE OF A MODEL HYDROPHILIC AMPHIPATHIC HELICAL BASIC PEPTIDE | | Descriptor: | HUMAN PLATELET FACTOR 4, SEGMENT 59-73 | | Authors: | Montserret, R, McLeish, M.J, Bockmann, A, Geourjon, C, Penin, F. | | Deposit date: | 1999-12-16 | | Release date: | 2000-01-12 | | Last modified: | 2024-04-10 | | Method: | SOLUTION NMR | | Cite: | Involvement of electrostatic interactions in the mechanism of peptide folding induced by sodium dodecyl sulfate binding.
Biochemistry, 39, 2000
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1DY8
 | | Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (inhibitor II) | | Descriptor: | N-[(benzyloxy)carbonyl]-L-isoleucyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide, NONSTRUCTURAL PROTEIN NS4A (P4), PROTEASE/HELICASE NS3 (P70) | | Authors: | Di Marco, S, Rizzi, M, Volpari, C, Walsh, M, Narjes, F, Colarusso, S, De Francesco, R, Matassa, V.G, Sollazzo, M. | | Deposit date: | 2000-01-31 | | Release date: | 2001-01-28 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Inhibition of the Hepatitis C Virus Ns3/4A Protease the Crystal Structures of Two Protease-Inhibitor Complexes
J.Biol.Chem., 275, 2000
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1DZM
 | | Porcine Odorant Binding Protein Complexed with benzoic acid phenylmethylester | | Descriptor: | BENZOIC ACID PHENYLMETHYLESTER, ODORANT-BINDING PROTEIN | | Authors: | Vincent, F, Spinelli, S, Ramoni, R, Grolli, S, Pelosi, P, Cambillau, C, Tegoni, M. | | Deposit date: | 2000-03-03 | | Release date: | 2000-12-06 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Complexes of Porcine Odorant Binding Protein with Odorant Molecules Belonging to Different Chemical Classes
J.Mol.Biol., 300, 2000
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1E02
 | | Porcine Odorant Binding Protein Complexed with undecanal | | Descriptor: | ODORANT-BINDING PROTEIN, UNDECANAL | | Authors: | Vincent, F, Spinelli, S, Cambillau, C, Tegoni, M. | | Deposit date: | 2000-03-09 | | Release date: | 2000-12-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Complexes of Porcine Odorant Binding Protein with Odorant Molecules Belonging to Different Chemical Classes
J.Mol.Biol., 300, 2000
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1DXL
 | | Dihydrolipoamide dehydrogenase of glycine decarboxylase from Pisum Sativum | | Descriptor: | DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Faure, M, Cohen-Addad, C, Bourguignon, J, Macherel, D, Neuburger, M, Douce, R. | | Deposit date: | 2000-01-10 | | Release date: | 2000-07-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Interaction between the Lipoamide-Containing H-Protein and the Lipoamide Dehydrogenase (L-Protein) of the Glycine Decarboxylase Multienzyme System. 2. Crystal Structure of H- and L-Proteins
Eur.J.Biochem., 267, 2000
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1E0H
 | | Inhibitor Protein Im9 bound to its partner E9 DNase | | Descriptor: | IMMUNITY PROTEIN FOR COLICIN E9 | | Authors: | Boetzel, R, Czisch, M, Kaptein, R, Hemmings, A.M, James, R, Kleanthous, C, Moore, G.R. | | Deposit date: | 2000-03-28 | | Release date: | 2000-10-30 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR investigation of the interaction of the inhibitor protein Im9 with its partner DNase.
Protein Sci., 9, 2000
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1E29
 | | PSII associated cytochrome C549 from Synechocystis sp. | | Descriptor: | CALCIUM ION, CYTOCHROME C549, HEME C | | Authors: | Frazao, C, Enguita, F.J, Coelho, R, Sheldrick, G.M. | | Deposit date: | 2000-05-19 | | Release date: | 2001-05-04 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.21 Å) | | Cite: | Crystal Structure of Low-Potential Cytochrome C549 from Synechocystis Sp. Pcc 6803 at 1.21A Resolution
J.Biol.Inorg.Chem., 6, 2001
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1E00
 | | Porcine Odorant Binding Protein Complexed with 2,6-dimethyl-7-octen-2-ol | | Descriptor: | 2,6-DIMETHYL-7-OCTEN-2-OL, ODORANT-BINDING PROTEIN | | Authors: | Vincent, F, Spinelli, S, Cambillau, C, Tegoni, M. | | Deposit date: | 2000-03-07 | | Release date: | 2000-12-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Complexes of Porcine Odorant Binding Protein with Odorant Molecules Belonging to Different Chemical Classes
J.Mol.Biol., 300, 2000
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1DQO
 | | Crystal structure of the cysteine rich domain of mannose receptor complexed with Acetylgalactosamine-4-sulfate | | Descriptor: | 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, MANNOSE RECEPTOR | | Authors: | Liu, Y, Chirino, A.J, Misulovin, Z, Leteux, C, Feizi, T, Nussenzweig, M.C, Bjorkman, P.J. | | Deposit date: | 2000-01-04 | | Release date: | 2000-05-10 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the cysteine-rich domain of mannose receptor complexed with a sulfated carbohydrate ligand.
J.Exp.Med., 191, 2000
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1DTJ
 | | CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN | | Descriptor: | RNA-BINDING NEUROONCOLOGICAL VENTRAL ANTIGEN 2 | | Authors: | Lewis, H.A, Chen, H, Edo, C, Buckanovich, R.J, Yang, Y.Y.L, Musunuru, K, Zhong, R, Darnell, R.B, Burley, S.K. | | Deposit date: | 2000-01-12 | | Release date: | 2000-02-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains.
Structure Fold.Des., 7, 1999
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1DUT
 | | FIV DUTP PYROPHOSPHATASE | | Descriptor: | DUTP PYROPHOSPHATASE, MAGNESIUM ION | | Authors: | Prasad, G.S, Stura, E.A, Mcree, D.E, Laco, G.S, Hasselkus-Light, C, Elder, J.H, Stout, C.D. | | Deposit date: | 1996-09-15 | | Release date: | 1997-01-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of dUTP pyrophosphatase from feline immunodeficiency virus.
Protein Sci., 5, 1996
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1DZP
 | | Porcine Odorant Binding Protein Complexed with diphenylmethanone | | Descriptor: | DIPHENYLMETHANONE, ODORANT-BINDING PROTEIN | | Authors: | Vincent, F, Spinelli, S, Cambillau, C, Tegoni, M. | | Deposit date: | 2000-03-06 | | Release date: | 2000-12-06 | | Last modified: | 2013-11-13 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Complexes of Porcine Odorant Binding Protein with Odorant Molecules Belonging to Different Chemical Classes
J.Mol.Biol., 300, 2000
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1DVA
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1E1S
 | | Human prion protein variant S170N | | Descriptor: | PRION PROTEIN | | Authors: | Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K. | | Deposit date: | 2000-05-10 | | Release date: | 2000-07-21 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR Structures of Three Single-Residue Variants of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
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1E4O
 | | Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question | | Descriptor: | MALTODEXTRIN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Watson, K.A, McCleverty, C, Geremia, S, Cottaz, S, Driguez, H, Johnson, L.N. | | Deposit date: | 2000-07-11 | | Release date: | 2000-08-16 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Phosphorylase Recognition and Phosphorylysis of its Oligosaccharide Substrate: Answers to a Long Outstanding Question
Embo J., 18, 1999
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1DY9
 | | Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (inhibitor I) | | Descriptor: | N-(tert-butoxycarbonyl)-L-alpha-glutamyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide, NONSTRUCTURAL PROTEIN NS4A (P4), PROTEASE/HELICASE NS3 (P70), ... | | Authors: | Di Marco, S, Rizzi, M, Volpari, C, Walsh, M, Narjes, F, Colarusso, S, De Francesco, R, Matassa, V.G, Sollazzo, M. | | Deposit date: | 2000-01-31 | | Release date: | 2001-01-28 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Inhibition of the Hepatitis C Virus Ns3/4A Protease the Crystal Structures of Two Protease-Inhibitor Complexes
J.Biol.Chem., 275, 2000
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1DZC
 | | High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures | | Descriptor: | FIBROBLAST GROWTH FACTOR 1 | | Authors: | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | | Deposit date: | 2000-02-24 | | Release date: | 2000-03-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
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1DHH
 | | NMR SOLUTION STRUCTURE OF THE DNA DUPLEX CONTAINING DNA/RNA HYBRID REGION, D(GG)R(AGAU)D(GAC)/D(GTCATCTCC) | | Descriptor: | DNA (5'-D(*GP*TP*CP*AP*TP*CP*TP*CP*C)-3'), DNA/RNA (5'-D(*GP*G)-R(P*AP*GP*AP*U)-D(P*GP*AP*C)-3') | | Authors: | Nishizaki, T, Iwai, S, Ohkubo, T, Kojima, C, Nakamura, H, Kyogoku, Y, Ohtsuka, E. | | Deposit date: | 1995-10-18 | | Release date: | 1996-04-03 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution Strucutres of DNA duplexes containing a DNA x RNA hybrid region, d(GG)r(AGAU)d(GAC) x d(GTCATCTCC) and d(GGAGA)r(UGAC) x d(GTCATCTCC).
Biochemistry, 35, 1996
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1DSD
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1DXP
 | | Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (apo structure) | | Descriptor: | GLYCEROL, NONSTRUCTURAL PROTEIN NS4A (P4), PROTEASE/HELICASE NS3 (P70), ... | | Authors: | Di Marco, S, Rizzi, M, Volpari, C, Walsh, M, Narjes, F, Colarusso, S, De Francesco, R, Matassa, V.G, Sollazzo, M. | | Deposit date: | 2000-01-13 | | Release date: | 2001-01-12 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Inhibition of the Hepatitis C Virus Ns3/4A Protease the Crystal Structures of Two Protease-Inhibitor Complexes
J.Biol.Chem., 275, 2000
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1DSC
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1E3G
 | | Human Androgen Receptor Ligand Binding in complex with the ligand metribolone (R1881) | | Descriptor: | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, ANDROGEN RECEPTOR | | Authors: | Matias, P.M, Donner, P, Coelho, R, Thomaz, M, Peixoto, C, Macedo, S, Otto, N, Joschko, S, Scholz, P, Wegg, A, Basler, S, Schafer, M, Ruff, M, Egner, U, Carrondo, M.A. | | Deposit date: | 2000-06-14 | | Release date: | 2001-06-14 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations.
J. Biol. Chem., 275, 2000
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