7NCR
 
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5DYQ
 | | AbyU L73M L139M | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, YD repeat-containing protein | | Authors: | Byrne, M.J, Race, P.R. | | Deposit date: | 2015-09-25 | | Release date: | 2016-06-08 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail.
J.Am.Chem.Soc., 138, 2016
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5BY7
 | | AbyA1 - tetronic acid condensing enzyme | | Descriptor: | 3-oxoacyl-ACP synthase III | | Authors: | Byrne, M.J, Race, P.R. | | Deposit date: | 2015-06-10 | | Release date: | 2016-06-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structure of AbyA1, a tetronic acid condensing enzyme from the Abyssomicin polyketide synthase.
To Be Published
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6SCO
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6SCL
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5NO5
 | | AbyA5 Wildtype | | Descriptor: | AbyA5 | | Authors: | Byrne, M.J, Race, P.R. | | Deposit date: | 2017-04-10 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6YRF
 | | Vip3Bc1 tetramer | | Descriptor: | Vegetative insecticidal protein | | Authors: | Thompson, R.F, Byrne, M.J, Iadanza, M.I, Arribas Perez, M, Maskell, D.P, George, R.M, Hesketh, E.L, Beales, P.A, Zack, M.D, Berry, C. | | Deposit date: | 2020-04-20 | | Release date: | 2021-03-17 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structures of an insecticidal Bt toxin reveal its mechanism of action on the membrane.
Nat Commun, 12, 2021
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6YRG
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4YWF
 | | AbyA5 | | Descriptor: | AbyA5 | | Authors: | Byrne, M.J, Race, P.R. | | Deposit date: | 2015-03-20 | | Release date: | 2016-06-29 | | Last modified: | 2019-06-19 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis.
Angew.Chem.Int.Ed.Engl., 58, 2019
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7NTX
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7OG6
 | | Structure of Alternanthera Mosaic VLP by cryoEM | | Descriptor: | Coat protein, RNA (5'-R(P*UP*UP*UP*UP*U)-3') | | Authors: | Byrne, M.J, Ranson, N.A, Lomonossoff, G.P, Thuenemann, E.C. | | Deposit date: | 2021-05-06 | | Release date: | 2021-06-23 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | A Replicating Viral Vector Greatly Enhances Accumulation of Helical Virus-Like Particles in Plants.
Viruses, 13, 2021
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5DYV
 | | AbyU - wildtype | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, YD repeat-containing protein | | Authors: | Race, P.R, Byrne, M.J. | | Deposit date: | 2015-09-25 | | Release date: | 2016-06-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail.
J.Am.Chem.Soc., 138, 2016
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6S73
 | | Crystal structure of Nek7 SRS mutant bound to compound 51 | | Descriptor: | 3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N}-[3-(dimethylamino)propyl]benzenesulfonamide, Serine/threonine-protein kinase Nek7 | | Authors: | Nasir, N, Byrne, M.J, Bhatia, C, Bayliss, R. | | Deposit date: | 2019-07-04 | | Release date: | 2020-06-10 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine.
Biochem.J., 477, 2020
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6SK9
 | | Nek2 bound to purine compound 51 | | Descriptor: | 3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N}-[3-(dimethylamino)propyl]benzenesulfonamide, GLYCEROL, Serine/threonine-protein kinase Nek2 | | Authors: | Bayliss, R, Byrne, M.J, Mas-Droux, C. | | Deposit date: | 2019-08-15 | | Release date: | 2020-06-17 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine.
Biochem.J., 477, 2020
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6QOZ
 | | CryoEM reconstruction of Cowpea Mosaic Virus (CPMV) bound to an Affimer reagent | | Descriptor: | Affimer binding protein, Cowpea mosaic virus large subunit, RNA2 polyprotein | | Authors: | Hesketh, E.L, Tiede, C, Adamson, H, Adams, T.L, Byrne, M.J, Meshcheriakova, Y, Lomonossoff, G.P, Kruse, I, McPherson, M.J, Tomlinson, D.C, Ranson, N.A. | | Deposit date: | 2019-02-13 | | Release date: | 2019-12-18 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Affimer reagents as tools in diagnosing plant virus diseases.
Sci Rep, 9, 2019
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6S75
 | | Crystal structure of Nek7 bound to compound 51 | | Descriptor: | 3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N}-[3-(dimethylamino)propyl]benzenesulfonamide, Serine/threonine-protein kinase Nek7 | | Authors: | Nasir, N, Bayliss, R. | | Deposit date: | 2019-07-04 | | Release date: | 2020-06-10 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine.
Biochem.J., 477, 2020
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6S76
 | | Crystal structure of human Nek7 | | Descriptor: | DI(HYDROXYETHYL)ETHER, Serine/threonine-protein kinase Nek7 | | Authors: | Nasir, N, Bayliss, R. | | Deposit date: | 2019-07-04 | | Release date: | 2020-06-10 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.38 Å) | | Cite: | Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine.
Biochem.J., 477, 2020
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8ACB
 | | CryoEM structure of sweet potato feathery mottle virus VLP | | Descriptor: | Genome polyprotein, Single-stranded RNA | | Authors: | Javed, A, Byrne, J.M, Ranson, N, Lomonosoff, G. | | Deposit date: | 2022-07-05 | | Release date: | 2023-05-17 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | CryoEM and stability analysis of virus-like particles of potyvirus and ipomovirus infecting a common host.
Commun Biol, 6, 2023
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8ACC
 | | CryoEM structure of sweet potato mild mottle virus VLP | | Descriptor: | Polyprotein, Single-stranded RNA | | Authors: | Javed, A, Byrne, B.M, Ranson, N, Lomonosoff, G. | | Deposit date: | 2022-07-05 | | Release date: | 2023-05-17 | | Last modified: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | CryoEM and stability analysis of virus-like particles of potyvirus and ipomovirus infecting a common host.
Commun Biol, 6, 2023
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8R5O
 | | Plastid-encoded RNA polymerase | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Webster, M.W, Pramanick, I, Vergara-Cruces, A. | | Deposit date: | 2023-11-17 | | Release date: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (2.49 Å) | | Cite: | Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
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8R6S
 | | Plastid-encoded RNA polymerase (Integrated model) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Webster, M.W, Pramanick, I, Vergara-Cruces, A. | | Deposit date: | 2023-11-22 | | Release date: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (2.49 Å) | | Cite: | Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
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8RDJ
 | | Plastid-encoded RNA polymerase transcription elongation complex (Integrated model) | | Descriptor: | DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Webster, M.W, Pramanick, I, Vergara-Cruces, A. | | Deposit date: | 2023-12-08 | | Release date: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
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8RAS
 | | Plastid-encoded RNA polymerase transcription elongation complex | | Descriptor: | DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Webster, M.W, Pramanick, I, Vergara-Cruces, A. | | Deposit date: | 2023-12-01 | | Release date: | 2024-03-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
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4Q1G
 | | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Polyketide biosynthesis enoyl-CoA isomerase PksI | | Authors: | Nair, A.V, Race, P.R, Till, M. | | Deposit date: | 2014-04-03 | | Release date: | 2015-05-06 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation.
Sci Rep, 10, 2020
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4Q1H
 | | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Polyketide biosynthesis enoyl-CoA isomerase PksI, ... | | Authors: | Nair, A.V, Race, P.R, Till, M. | | Deposit date: | 2014-04-03 | | Release date: | 2015-05-06 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation.
Sci Rep, 10, 2020
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