6S76

Crystal structure of human Nek7

Summary for 6S76

Entry DOI	10.2210/pdb6s76/pdb
Related	6S73 6S75
Descriptor	Serine/threonine-protein kinase Nek7, DI(HYDROXYETHYL)ETHER (2 entities in total)
Functional Keywords	kinase, cell cycle
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	142786.57
Authors	Nasir, N.,Bayliss, R. (deposition date: 2019-07-04, release date: 2020-06-10, Last modification date: 2024-01-24)
Primary citation	Byrne, M.J.,Nasir, N.,Basmadjian, C.,Bhatia, C.,Cunnison, R.F.,Carr, K.H.,Mas-Droux, C.,Yeoh, S.,Cano, C.,Bayliss, R. Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine. Biochem.J., 477:1525-1539, 2020 Cited by PubMed: 32242624 DOI: 10.1042/BCJ20200128 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.38 Å)

Structure validation