4YDK
 
 | | Crystal structure of broadly and potently neutralizing antibody C38-VRC16.01 in complex with HIV-1 clade AE strain 93TH057 gp120 | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Zhou, T, Moquin, S, Zheng, A, Kwong, P.D. | | Deposit date: | 2015-02-22 | | Release date: | 2015-06-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.051 Å) | | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
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4YDJ
 | | Crystal structure of broadly and potently neutralizing antibody 44-VRC13.01 in complex with HIV-1 clade AE strain 93TH057 gp120 | | Descriptor: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Zhou, T, Moquin, S, Kwong, P.D. | | Deposit date: | 2015-02-22 | | Release date: | 2015-06-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.308 Å) | | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
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8V2E
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4YDL
 | | Crystal structure of broadly and potently neutralizing antibody C38-VRC18.02 in complex with HIV-1 clade AE strain 93TH057gp120 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | | Authors: | Zhou, T, Srivatsan, S, Kwong, P.D. | | Deposit date: | 2015-02-22 | | Release date: | 2015-06-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
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4YFL
 | | Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 1B2530 in complex with HIV-1 clade A/E 93TH057 gp120 | | Descriptor: | 1B2530 Light chain, 1B2530 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Acharya, P, Zhou, T, Moquin, S, Kwong, P.D. | | Deposit date: | 2015-02-25 | | Release date: | 2015-06-03 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.387 Å) | | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
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4YE4
 | | Crystal Structure of Neutralizing Antibody HJ16 in Complex with HIV-1 gp120 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HT593.1 gp120, Heavy chain human antibody HJ16, ... | | Authors: | Kwong, P.D, Chen, L, Zhou, T. | | Deposit date: | 2015-02-23 | | Release date: | 2015-07-22 | | Last modified: | 2022-03-30 | | Method: | X-RAY DIFFRACTION (2.72 Å) | | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
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8VBR
 | | Structure of bovine anti-HIV Fab ElsE11 | | Descriptor: | Bovine Fab ElsE11 light chain, Bovine Fab Else11 heavy chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8VBM
 | | Structure of bovine anti-HIV Fab ElsE7 | | Descriptor: | Bovine Fab ElsE7 heavy chain, Bovine Fab ElsE7 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8VBK
 | | Structure of bovine anti-HIV Fab ElsE5 | | Descriptor: | Bovine Fab ElsE5 heavy chain, Bovine Fab ElsE5 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8VBJ
 | | Structure of bovine anti-HIV Fab ElsE2 | | Descriptor: | Bovine Fab ElsE2 heavy chain, Bovine Fab ElsE2 light chain, POTASSIUM ION, ... | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8VBN
 | | Structure of bovine anti-HIV Fab ElsE8 | | Descriptor: | Bovine Fab ElsE8 heavy chain, Bovine Fab ElsE8 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8VBP
 | | Structure of bovine anti-HIV Fab Bess4 | | Descriptor: | Bovine Fab Bess4 heavy chain, Bovine Fab Bess4 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8VBQ
 | | Structure of bovine anti-HIV Fab Bess7 | | Descriptor: | Bovine Fab Bess7 heavy chain, Bovine Fab Bess7 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8V4I
 | | Structure of bovine anti-HIV Fab ElsE1 | | Descriptor: | ElsE1 Fab heavy chain, ElsE1 Fab light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-11-29 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8VBO
 | | Structure of bovine anti-HIV Fab ElsE9 | | Descriptor: | Bovine Fab ElsE9 heavy chain, Bovine Fab ElsE9 light chain, GLYCEROL, ... | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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8VBL
 | | Structure of bovine anti-HIV Fab ElsE6 | | Descriptor: | Bovine Fab ElsE6 heavy chain, Bovine Fab ElsE6 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire
To Be Published
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5AWN
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6DFH
 | | BG505 MD64 N332-GT2 SOSIP trimer in complex with germline-reverted BG18 fragment antigen binding | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | Authors: | Ozorowski, G, Steichen, J.M, Schief, W.R, Ward, A.B. | | Deposit date: | 2018-05-14 | | Release date: | 2019-11-06 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.85 Å) | | Cite: | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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6DID
 | | HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | Authors: | Turner, H.L, Cottrell, C.A, Oyen, D, Wilson, I.A, Ward, A.B. | | Deposit date: | 2018-05-23 | | Release date: | 2018-09-05 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.71 Å) | | Cite: | Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
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6DFG
 | | BG505 MD39 SOSIP trimer in complex with mature BG18 fragment antigen binding | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | Authors: | Ozorowski, G, Steichen, J.M, Schief, W.R, Ward, A.B. | | Deposit date: | 2018-05-14 | | Release date: | 2019-11-06 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.42 Å) | | Cite: | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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6CE0
 | | Crystal structure of a HIV-1 clade B tier-3 isolate H078.14 UFO-BG Env trimer in complex with broadly neutralizing Fabs PGT124 and 35O22 at 4.6 Angstrom | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ... | | Authors: | Kumar, S, Sarkar, A, Wilson, I.A. | | Deposit date: | 2018-02-09 | | Release date: | 2018-12-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (4.602 Å) | | Cite: | HIV-1 vaccine design through minimizing envelope metastability.
Sci Adv, 4, 2018
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6CJK
 | | Anti HIV Fab 10A | | Descriptor: | ACETATE ION, GLYCEROL, Immunoglobulin Fab heavy chain, ... | | Authors: | Hangartner, L, Ward, A.B, Wilson, I.A, Oyen, D. | | Deposit date: | 2018-02-26 | | Release date: | 2018-08-15 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (1.795 Å) | | Cite: | Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
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6VSL
 | | Crystal structure of a human fucosylated IgG1 Fc expressed in tobacco plants (Nicotiana benthamiana) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Tolbert, W.D, Pazgier, M. | | Deposit date: | 2020-02-11 | | Release date: | 2021-02-17 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Enhanced Ability of Plant-Derived PGT121 Glycovariants To Eliminate HIV-1-Infected Cells.
J.Virol., 95, 2021
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6VSZ
 | | Crystal structure of a human afucosylated IgG1 Fc expressed in tobacco plants (Nicotiana benthamiana) | | Descriptor: | Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Tolbert, W.D, Pazgier, M. | | Deposit date: | 2020-02-12 | | Release date: | 2021-02-17 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Enhanced Ability of Plant-Derived PGT121 Glycovariants To Eliminate HIV-1-Infected Cells.
J.Virol., 95, 2021
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6XY4
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