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3HQJ
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BU of 3hqj by Molmil
Structure-function analysis of Mycobacterium tuberculosis acyl carrier protein synthase (AcpS).
分子名称: COENZYME A, Holo-[acyl-carrier-protein] synthase, MAGNESIUM ION
著者Dym, O, Albeck, S, Peleg, Y, Schwarz, A, Shakked, Z, Burstein, Y, Zimhony, O, Israel Structural Proteomics Center (ISPC)
登録日2009-06-07
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis.
J.Mol.Biol., 393, 2009
1Y9A
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BU of 1y9a by Molmil
Alcohol Dehydrogenase from Entamoeba histolotica in complex with cacodylate
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CACODYLATE ION, ...
著者Shimon, L.J, Peretz, M, Goihberg, E, Burstein, Y, Frolow, F.
登録日2004-12-15
公開日2006-01-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structure of alcohol dehydrogenase from Entamoeba histolytica.
Acta Crystallogr.,Sect.D, 62, 2006
3FPL
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BU of 3fpl by Molmil
Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of C. beijerinckii ADH by T. brockii ADH
分子名称: 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ...
著者Felix, F, Goihberg, E, Shimon, L, Burstein, Y.
登録日2009-01-05
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms
Biochemistry, 49, 2010
3FPC
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BU of 3fpc by Molmil
Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-294 of T. brockii ADH by E. histolytica ADH
分子名称: 1,2-ETHANEDIOL, CACODYLATE ION, IMIDAZOLE, ...
著者Felix, F, Goihberg, E, Shimon, L, Burstein, Y.
登録日2009-01-05
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms
Biochemistry, 49, 2010
3FSR
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BU of 3fsr by Molmil
Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, NADP-dependent alcohol dehydrogenase, ...
著者Frolow, F, Greenblatt, H, Goihberg, E, Burstein, Y.
登録日2009-01-11
公開日2010-01-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms
Biochemistry, 49, 2010
3FTN
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BU of 3ftn by Molmil
Q165E/S254K Double Mutant Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Frolow, F, Goihberg, E, Shimon, L, Burstein, Y.
登録日2009-01-13
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.192 Å)
主引用文献Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms.
Biochemistry, 49, 2010
1LLU
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BU of 1llu by Molmil
THE TERNARY COMPLEX OF PSEUDOMONAS AERUGINOSA ALCOHOL DEHYDROGENASE WITH ITS COENZYME AND WEAK SUBSTRATE
分子名称: 1,2-ETHANEDIOL, Alcohol Dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Levin, I, Meiri, G, Peretz, M, Frolow, F, Burstein, Y.
登録日2002-04-30
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The ternary complex of Pseudomonas aeruginosa alcohol dehydrogenase with NADH and ethylene glycol.
Protein Sci., 13, 2004
1JQB
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BU of 1jqb by Molmil
Alcohol Dehydrogenase from Clostridium Beijerinckii: Crystal Structure of Mutant with Enhanced Thermal Stability
分子名称: NADP-dependent Alcohol Dehydrogenase, ZINC ION
著者Levin, I, Frolow, F, Bogin, O, Peretz, M, Hacham, Y, Burstein, Y.
登録日2001-08-05
公開日2002-11-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural basis for the enhanced thermal stability of alcohol dehydrogenase mutants from the mesophilic bacterium Clostridium beijerinckii: contribution of salt bridging
Protein Sci., 11, 2002
2NVB
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BU of 2nvb by Molmil
Contribution of Pro275 to the Thermostability of the Alcohol Dehydrogenases (ADHs)
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent alcohol dehydrogenase, ZINC ION
著者Goihberg, E, Tel-Or, S, Peretz, M, Frolow, F, Dym, O, Burstein, Y, Israel Structural Proteomics Center (ISPC)
登録日2006-11-12
公開日2007-11-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution
Proteins, 72, 2008
2OUI
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BU of 2oui by Molmil
D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica
分子名称: 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ...
著者Frolow, F, Shimon, L, Burstein, Y, Goihberg, E, Peretz, M, Dym, O.
登録日2007-02-11
公開日2008-02-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.
Proteins, 72, 2008
1PED
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BU of 1ped by Molmil
BACTERIAL SECONDARY ALCOHOL DEHYDROGENASE (APO-FORM)
分子名称: NADP-DEPENDENT ALCOHOL DEHYDROGENASE, ZINC ION
著者Korkhin, Y, Frolow, F.
登録日1995-12-28
公開日1997-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystalline alcohol dehydrogenases from the mesophilic bacterium Clostridium beijerinckii and the thermophilic bacterium Thermoanaerobium brockii: preparation, characterization and molecular symmetry.
Acta Crystallogr.,Sect.D, 52, 1996
1YKF
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BU of 1ykf by Molmil
NADP-DEPENDENT ALCOHOL DEHYDROGENASE FROM THERMOANAEROBIUM BROCKII
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-DEPENDENT ALCOHOL DEHYDROGENASE, ZINC ION
著者Korkhin, Y, Frolow, F.
登録日1996-03-25
公開日1998-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献NADP-dependent bacterial alcohol dehydrogenases: crystal structure, cofactor-binding and cofactor specificity of the ADHs of Clostridium beijerinckii and Thermoanaerobacter brockii.
J.Mol.Biol., 278, 1998
1E3J
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BU of 1e3j by Molmil
Ketose reductase (sorbitol dehydrogenase) from silverleaf whitefly
分子名称: BORIC ACID, NADP(H)-DEPENDENT KETOSE REDUCTASE, PHOSPHATE ION, ...
著者Banfield, M.J, Salvucci, M.E, Baker, E.N, Smith, C.A.
登録日2000-06-19
公開日2001-02-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Nadp(H)-Dependent Ketose Reductase from Besimia Argentifolii at 2.3 Angstrom Resolution
J.Mol.Biol., 306, 2001
1BXZ
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BU of 1bxz by Molmil
CRYSTAL STRUCTURE OF A THERMOPHILIC ALCOHOL DEHYDROGENASE SUBSTRATE COMPLEX FROM THERMOANAEROBACTER BROCKII
分子名称: 2-BUTANOL, CHLORIDE ION, MAGNESIUM ION, ...
著者Li, C, Heatwole, J, Soelaiman, S, Shoham, M.
登録日1998-10-09
公開日2000-02-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Crystal structure of a thermophilic alcohol dehydrogenase substrate complex suggests determinants of substrate specificity and thermostability.
Proteins, 37, 1999
2B83
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BU of 2b83 by Molmil
A single amino acid substitution in the Clostridium beijerinckii alcohol dehydrogenase is critical for thermostabilization
分子名称: NADP-dependent alcohol dehydrogenase, ZINC ION
著者Goihberg, E, Dym, O, Israel Structural Proteomics Center (ISPC)
登録日2005-10-06
公開日2006-09-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A single proline substitution is critical for the thermostabilization of Clostridium beijerinckii alcohol dehydrogenase.
Proteins, 66, 2006
1KEV
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BU of 1kev by Molmil
STRUCTURE OF NADP-DEPENDENT ALCOHOL DEHYDROGENASE
分子名称: NADP-DEPENDENT ALCOHOL DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC ION
著者Korkhin, Y, Frolow, F.
登録日1996-10-21
公開日1997-10-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystalline alcohol dehydrogenases from the mesophilic bacterium Clostridium beijerinckii and the thermophilic bacterium Thermoanaerobium brockii: preparation, characterization and molecular symmetry.
Acta Crystallogr.,Sect.D, 52, 1996
6TMN
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BU of 6tmn by Molmil
Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond
分子名称: CALCIUM ION, N-[(2R,4S)-4-hydroxy-2-(2-methylpropyl)-4-oxido-7-oxo-9-phenyl-3,8-dioxa-6-aza-4-phosphanonan-1-oyl]-L-leucine, THERMOLYSIN, ...
著者Tronrud, D.E, Holden, H.M, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond.
Science, 235, 1987
7TLN
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BU of 7tln by Molmil
STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR
分子名称: 2-(ACETYL-HYDROXY-AMINO)-4-METHYL-PENTANOIC ACID METHYL ESTER, CALCIUM ION, THERMOLYSIN, ...
著者Matthews, B.W, Holmes, M.A, Tronrud, D.E.
登録日1983-01-27
公開日1983-03-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor.
Biochemistry, 22, 1983
4TLN
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BU of 4tln by Molmil
BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称: CALCIUM ION, L-LEUCYL-HYDROXYLAMINE, THERMOLYSIN, ...
著者Matthews, B.W, Holmes, M.A.
登録日1982-02-08
公開日1982-05-26
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.
Biochemistry, 20, 1981
4TMN
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BU of 4tmn by Molmil
SLOW-AND FAST-BINDING INHIBITORS OF THERMOLYSIN DISPLAY DIFFERENT MODES OF BINDING. CRYSTALLOGRAPHIC ANALYSIS OF EXTENDED PHOSPHONAMIDATE TRANSITION-STATE ANALOGUES
分子名称: CALCIUM ION, N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine, THERMOLYSIN, ...
著者Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
3TMN
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BU of 3tmn by Molmil
THE BINDING OF L-VALYL-L-TRYPTOPHAN TO CRYSTALLINE THERMOLYSIN ILLUSTRATES THE MODE OF INTERACTION OF A PRODUCT OF PEPTIDE HYDROLYSIS
分子名称: CALCIUM ION, THERMOLYSIN, TRYPTOPHAN, ...
著者Holden, H.M, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis.
J.Biol.Chem., 263, 1988
5TLN
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BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称: CALCIUM ION, HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE, THERMOLYSIN, ...
著者Matthews, B.W, Holmes, M.A.
登録日1982-02-08
公開日1982-05-26
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.
Biochemistry, 20, 1981
5TMN
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BU of 5tmn by Molmil
Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues
分子名称: CALCIUM ION, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-leucine, THERMOLYSIN, ...
著者Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
1JVB
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ALCOHOL DEHYDROGENASE FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS
分子名称: NAD(H)-DEPENDENT ALCOHOL DEHYDROGENASE, ZINC ION
著者Esposito, L, Sica, F, Zagari, A, Mazzarella, L.
登録日2001-08-29
公開日2002-08-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution.
J.Mol.Biol., 318, 2002
8TLN
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STRUCTURAL COMPARISON SUGGESTS THAT THERMOLYSIN AND RELATED NEUTRAL PROTEASES UNDERGO HINGE-BENDING MOTION DURING CATALYSIS
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者Tronrud, D, Matthews, B.W.
登録日1993-09-01
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis.
Biochemistry, 31, 1992

 

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