1X77
 
 | | Crystal structure of a NAD(P)H-dependent FMN reductase complexed with FMN | | Descriptor: | FLAVIN MONONUCLEOTIDE, conserved hypothetical protein | | Authors: | Agarwal, R, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2004-08-13 | | Release date: | 2004-08-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure determination of an FMN reductase from Pseudomonas aeruginosa PA01 using sulfur anomalous signal.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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1XBB
 | | Crystal structure of the syk tyrosine kinase domain with Gleevec | | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Tyrosine-protein kinase SYK | | Authors: | Nienaber, V.L, Atwell, S, Adams, J.M, Badger, J, Buchanan, M.D, Feil, I.K, Froning, K.J, Gao, X, Hendle, J, Keegan, K, Leon, B.C, Muller-Deickmann, H.J, Noland, B.W, Post, K, Rajashankar, K.R, Ramos, A, Russell, M, Burley, S.K, Buchanan, S.G. | | Deposit date: | 2004-08-30 | | Release date: | 2004-11-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | A Novel Mode of Gleevec Binding Is Revealed by the Structure of Spleen Tyrosine Kinase
J.Biol.Chem., 279, 2004
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1XBC
 | | Crystal structure of the syk tyrosine kinase domain with Staurosporin | | Descriptor: | STAUROSPORINE, Tyrosine-protein kinase SYK | | Authors: | Badger, J, Atwell, S, Adams, J.M, Buchanan, M.D, Feil, I.K, Froning, K.J, Gao, X, Hendle, J, Keegan, K, Leon, B.C, Muller-Deickmann, H.J, Nienaber, V.L, Noland, B.W, Post, K, Rajashankar, K.R, Ramos, A, Russell, M, Burley, S.K, Buchanan, S.G. | | Deposit date: | 2004-08-30 | | Release date: | 2004-11-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase
J.Biol.Chem., 279, 2004
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1XCB
 | | X-ray Structure of a Rex-Family Repressor/NADH Complex from Thermus Aquaticus | | Descriptor: | CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Redox-sensing transcriptional repressor rex | | Authors: | Sickmier, E.A, Brekasis, D, Paranawithana, S, Bonanno, J.B, Burley, S.K, Paget, M.S, Kielkopf, C.L, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2004-09-01 | | Release date: | 2004-09-28 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | X-Ray Structure of a Rex-Family Repressor/NADH Complex: Insights into the Mechanism of Redox Sensing
Structure, 13, 2005
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1XLY
 | | X-RAY STRUCTURE OF THE RNA-BINDING PROTEIN SHE2p | | Descriptor: | SHE2p | | Authors: | Niessing, D, Huettelmaier, S, Zenklusen, D, Singer, R.H, Burley, S.K. | | Deposit date: | 2004-09-30 | | Release date: | 2004-11-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | She2p is a novel RNA binding protein with a basic helical hairpin motif
Cell(Cambridge,Mass.), 119, 2004
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1RTT
 | | Crystal structure determination of a putative NADH-dependent reductase using sulfur anomalous signal | | Descriptor: | SULFATE ION, conserved hypothetical protein | | Authors: | Agarwal, R, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2003-12-10 | | Release date: | 2004-08-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Structure determination of an FMN reductase from Pseudomonas aeruginosa PA01 using sulfur anomalous signal.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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1S0U
 | | eIF2gamma apo | | Descriptor: | Translation initiation factor 2 gamma subunit, ZINC ION | | Authors: | Roll-Mecak, A, Alone, P, Cao, C, Dever, T.E, Burley, S.K. | | Deposit date: | 2004-01-04 | | Release date: | 2004-01-20 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-ray Structure of Translation Initiation Factor eIF2gamma: IMPLICATIONS FOR tRNA AND eIF2alpha BINDING.
J.Biol.Chem., 279, 2004
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1RXD
 | | Crystal structure of human protein tyrosine phosphatase 4A1 | | Descriptor: | protein tyrosine phosphatase type IVA, member 1; Protein tyrosine phosphatase IVA1 | | Authors: | Sun, J.P, Fedorov, A.A, Almo, S.C, Zhang, Z.Y, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2003-12-18 | | Release date: | 2004-12-28 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
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2KUC
 | | Solution Structure of a putative disulphide-isomerase from Bacteroides thetaiotaomicron | | Descriptor: | Putative disulphide-isomerase | | Authors: | Harris, R, Foti, R, Seidel, R.D, Bonanno, J.B, Freeman, J, Bain, K.T, Sauder, J.M, Burley, S.K, Girvin, M.E, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2010-02-17 | | Release date: | 2010-03-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a putative disulphide-isomerase from Bacteroides thetaiotaomicron
To be Published
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1Y9I
 | | Crystal structure of low temperature requirement C protein from Listeria monocytogenes | | Descriptor: | CALCIUM ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2004-12-15 | | Release date: | 2004-12-28 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of phosphatidylglycerophosphatase (PGPase), a putative membrane-bound lipid phosphatase, reveals a novel binuclear metal binding site and two "proton wires".
Proteins, 64, 2006
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1SG9
 | | Crystal structure of Thermotoga maritima protein HEMK, an N5-glutamine methyltransferase | | Descriptor: | GLUTAMINE, S-ADENOSYLMETHIONINE, hemK protein | | Authors: | Agarwal, R, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2004-02-23 | | Release date: | 2004-08-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A novel mode of dimerization via formation of a glutamate anhydride crosslink in a protein crystal structure.
Proteins, 71, 2008
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2L5L
 | | Solution Structure of Thioredoxin from Bacteroides Vulgatus | | Descriptor: | Thioredoxin | | Authors: | Harris, R, Foti, R, Seidel, R.D, Bonanno, J.B, Freeman, J, Bain, K.T, Sauder, J.M, Burley, S.K, Girvin, M.E, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC), New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2010-11-02 | | Release date: | 2010-11-24 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Thioredoxin from Bacteroides Vulgatus
To be Published
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1SGM
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2L5O
 | | Solution Structure of a Putative Thioredoxin from Neisseria meningitidis | | Descriptor: | Putative thioredoxin | | Authors: | Harris, R, Foti, R, Seidel, R.D, Bonanno, J.B, Freeman, J, Bain, K.T, Sauder, J.M, Burley, S.K, Girvin, M.E, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC), New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2010-11-03 | | Release date: | 2010-12-15 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a Putative Thioredoxin from Neisseria meningitidis
To be Published
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2L57
 | | Solution Structure of an Uncharacterized Thioredoin-like Protein from Clostridium perfringens | | Descriptor: | Uncharacterized protein | | Authors: | Harris, R, Foti, R, Seidel, R.D, Bonanno, J.B, Freeman, J, Bain, K.T, Sauder, J.M, Burley, S.K, Girvin, M.E, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC), New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2010-10-26 | | Release date: | 2010-11-17 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of an Uncharacterized Thioredoin-like Protein from Clostridium perfringens
To be Published
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1TK9
 | | Crystal Structure of Phosphoheptose isomerase 1 | | Descriptor: | Phosphoheptose isomerase 1 | | Authors: | Rajashankar, K.R, Solorzano, V, Kniewel, R, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2004-06-08 | | Release date: | 2004-06-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of two putative phosphoheptose isomerases.
Proteins, 63, 2006
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1TAF
 | | DROSOPHILA TBP ASSOCIATED FACTORS DTAFII42/DTAFII62 HETEROTETRAMER | | Descriptor: | TFIID TBP ASSOCIATED FACTOR 42, TFIID TBP ASSOCIATED FACTOR 62, ZINC ION | | Authors: | Xie, X, Kokubo, T, Cohen, S.L, Mirza, U.A, Hoffmann, A, Chait, B.T, Roeder, R.G, Nakatani, Y, Burley, S.K. | | Deposit date: | 1996-06-01 | | Release date: | 1996-12-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural similarity between TAFs and the heterotetrameric core of the histone octamer.
Nature, 380, 1996
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1Z2L
 | | Crystal structure of Allantoate-amidohydrolase from E.coli K12 in complex with substrate Allantoate | | Descriptor: | ALLANTOATE ION, Allantoate amidohydrolase, SULFATE ION, ... | | Authors: | Agarwal, R, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2005-03-08 | | Release date: | 2005-03-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural analysis of a ternary complex of allantoate amidohydrolase from Escherichia coli reveals its mechanics.
J.Mol.Biol., 368, 2007
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1ZCC
 | | Crystal structure of glycerophosphodiester phosphodiesterase from Agrobacterium tumefaciens str.C58 | | Descriptor: | ACETATE ION, SULFATE ION, glycerophosphodiester phosphodiesterase | | Authors: | Krishnamurthy, N.R, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2005-04-11 | | Release date: | 2005-05-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of glycerophosphodiester phosphodiesterase from Agrobacterium tumefaciens by SAD with a large asymmetric unit.
Proteins, 65, 2006
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1TWI
 | | Crystal structure of Diaminopimelate Decarboxylase from m. jannaschii in co-complex with L-lysine | | Descriptor: | Diaminopimelate decarboxylase, LYSINE, MAGNESIUM ION, ... | | Authors: | Rajashankar, K.R, Ray, S.S, Bonanno, J.B, Pinho, M.G, He, G, De Lencastre, H, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2004-07-01 | | Release date: | 2004-07-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor
Structure, 10, 2002
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1ZY4
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant in Apo Form. | | Descriptor: | GLYCEROL, Serine/threonine-protein kinase GCN2 | | Authors: | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | Deposit date: | 2005-06-09 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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1UBD
 | | CO-CRYSTAL STRUCTURE OF HUMAN YY1 ZINC FINGER DOMAIN BOUND TO THE ADENO-ASSOCIATED VIRUS P5 INITIATOR ELEMENT | | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*TP*CP*TP*CP*CP*AP*TP*TP*TP*TP*GP*AP*A P*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*CP*AP*AP*AP*AP*TP*GP*GP*AP*GP*AP*C P*CP*CP*T)-3'), PROTEIN (YY1 ZINC FINGER DOMAIN), ... | | Authors: | Houbaviy, H.B, Usheva, A, Shenk, T, Burley, S.K. | | Deposit date: | 1996-10-04 | | Release date: | 1996-12-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator.
Proc.Natl.Acad.Sci.USA, 93, 1996
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1UG3
 | | C-terminal portion of human eIF4GI | | Descriptor: | eukaryotic protein synthesis initiation factor 4G | | Authors: | Bellsolell, L, Cho-Park, P.F, Poulin, F, Sonenberg, N, Burley, S.K. | | Deposit date: | 2003-06-11 | | Release date: | 2005-03-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Two structurally atypical HEAT domains in the C-terminal portion of human eIF4G support binding to eIF4A and Mnk1
Structure, 14, 2006
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1ZYC
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type in Apo Form. | | Descriptor: | Serine/threonine-protein kinase GCN2 | | Authors: | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | Deposit date: | 2005-06-09 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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1ZY5
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant Complexed with AMPPNP. | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase GCN2 | | Authors: | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | Deposit date: | 2005-06-09 | | Release date: | 2005-06-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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