1TWI

Crystal structure of Diaminopimelate Decarboxylase from m. jannaschii in co-complex with L-lysine

Summary for 1TWI

• Entry DOI: 10.2210/pdb1twi/pdb
• Related: 1TUF
• Descriptor: Diaminopimelate decarboxylase, PYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: antibiotic resistance, diaminopimelate decarboxylase, lysine biosynthesis, structural genomics, nysgxrc, t135, psi, protein structure initiative, new york sgx research center for structural genomics, lyase
• Biological source: Methanocaldococcus jannaschii
• Total number of polymer chains: 4
• Total formula weight: 195663.78

Authors

Rajashankar, K.R.,Ray, S.S.,Bonanno, J.B.,Pinho, M.G.,He, G.,De Lencastre, H.,Tomasz, A.,Burley, S.K.,New York SGX Research Center for Structural Genomics (NYSGXRC) (deposition date: 2004-07-01, release date: 2004-07-27, Last modification date: 2023-08-23)

• Primary citation: Rajashankar, K.R.,Ray, S.S.,Bonanno, J.B.,Pinho, M.G.,He, G.,De Lencastre, H.,Tomasz, A.,Burley, S.K.; Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor; Structure, 10:1499-1508, 2002; PubMed: 12429091; DOI: 10.1016/S0969-2126(02)00880-8

Experimental method

X-RAY DIFFRACTION (2 Å)