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4V3L
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BU of 4v3l by Molmil
RNF38-UB-UbcH5B-Ub complex
分子名称: 1,2-ETHANEDIOL, E3 UBIQUITIN-PROTEIN LIGASE RNF38, POLYUBIQUITIN-C, ...
著者Buetow, L, Gabrielsen, M, Anthony, N.G, Dou, H, Patel, A, Aitkenhead, H, Sibbet, G.J, Smith, B.O, Huang, D.T.
登録日2014-10-20
公開日2015-04-08
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Activation of a Primed Ring E3-E2-Ubiquitin Complex by Non-Covalent Ubiquitin.
Mol.Cell, 58, 2015
4V3K
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BU of 4v3k by Molmil
RNF38-UbcH5B-UB complex
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE RNF38, ...
著者Buetow, L, Gabrielsen, M, Anthony, N.G, Dou, H, Patel, A, Aitkenhead, H, Sibbet, G.J, Smith, B.O, Huang, D.T.
登録日2014-10-20
公開日2015-04-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Activation of a Primed Ring E3-E2-Ubiquitin Complex by Non-Covalent Ubiquitin.
Mol.Cell, 58, 2015
1HQ0
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BU of 1hq0 by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF E.COLI CYTOTOXIC NECROTIZING FACTOR TYPE 1
分子名称: CYTOTOXIC NECROTIZING FACTOR 1, PHOSPHATE ION
著者Buetow, L, Flatau, G, Chiu, K, Boquet, P, Ghosh, P.
登録日2000-12-13
公開日2001-07-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1.
Nat.Struct.Biol., 8, 2001
1HZG
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BU of 1hzg by Molmil
CRYSTAL STRUCTURE OF THE INACTIVE C866S MUTANT OF THE CATALYTIC DOMAIN OF E. COLI CYTOTOXIC NECROTIZING FACTOR 1
分子名称: CYTOTOXIC NECROTIZING FACTOR 1, PHOSPHATE ION
著者Buetow, L, Flatau, G, Chiu, K, Boquet, P, Ghosh, P.
登録日2001-01-24
公開日2001-07-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1.
Nat.Struct.Biol., 8, 2001
2UZH
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BU of 2uzh by Molmil
Mycobacterium smegmatis 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF)
分子名称: 1,2-ETHANEDIOL, 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ...
著者Buetow, L, Brown, A.C, Parish, T, Hunter, W.N.
登録日2007-04-27
公開日2007-11-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structure of Mycobacteria 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase, an Essential Enzyme, Provides a Platform for Drug Discovery.
Bmc Struct.Biol., 7, 2007
2IU9
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BU of 2iu9 by Molmil
Chlamydia trachomatis LpxD with 100mM UDPGlcNAc (Complex II)
分子名称: BETA-MERCAPTOETHANOL, PALMITIC ACID, SULFATE ION, ...
著者Buetow, L, Smith, T.K, Dawson, A, Fyffe, S, Hunter, W.N.
登録日2006-05-30
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure and Reactivity of Lpxd, the N-Acyltransferase of Lipid a Biosynthesis
Proc.Natl.Acad.Sci.USA, 104, 2007
2IUA
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BU of 2iua by Molmil
C. trachomatis LpxD
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PALMITIC ACID, SULFATE ION, ...
著者Buetow, L, Smith, T.K, Dawson, A, Fyffe, S, Hunter, W.N.
登録日2006-05-30
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and Reactivity of Lpxd, the N-Acyltransferase of Lipid a Biosynthesis
Proc.Natl.Acad.Sci.USA, 104, 2007
2IU8
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BU of 2iu8 by Molmil
Chlamydia trachomatis LpxD with 25mM UDPGlcNAc (Complex I)
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, PALMITIC ACID, ...
著者Buetow, L, Smith, T.K, Dawson, A, Fyffe, S, Hunter, W.N.
登録日2006-05-30
公開日2007-02-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and Reactivity of Lpxd, the N-Acyltransferase of Lipid a Biosynthesis
Proc.Natl.Acad.Sci.USA, 104, 2007
2J65
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BU of 2j65 by Molmil
Structure of LpxC from Aquifex aeolicus in complex with UDP
分子名称: CHLORIDE ION, MYRISTIC ACID, UDP-3-O-[3-HYDROXYMYRISTOYL] N-ACETYLGLUCOSAMINE DEACETYLASE, ...
著者Buetow, L, Dawson, A, Hunter, W.N.
登録日2006-09-26
公開日2006-11-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Nucleotide-Binding Site of Aquifex Aeolicus Lpxc.
Acta Crystallogr.,Sect.F, 62, 2006
5J3X
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BU of 5j3x by Molmil
Structure of c-CBL Y371F
分子名称: CALCIUM ION, E3 ubiquitin-protein ligase CBL, ZINC ION
著者Huang, D.T, Buetow, L, Dou, H.
登録日2016-03-31
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.
Bmc Biol., 14, 2016
6QK9
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BU of 6qk9 by Molmil
A dimeric ubiquitin formed by a single amino acid substitution
分子名称: Polyubiquitin-B
著者Gabrielsen, M, Kowalczyk, D, Buetow, L, Huang, D.T.
登録日2019-01-28
公開日2019-07-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.231 Å)
主引用文献Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation.
Structure, 27, 2019
2AWH
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BU of 2awh by Molmil
Human Nuclear Receptor-Ligand Complex 1
分子名称: Peroxisome proliferator activated receptor delta, VACCENIC ACID, heptyl beta-D-glucopyranoside
著者Fyffe, S.A, Alphey, M.S, Buetow, L, Smith, T.K, Ferguson, M.A.J, Sorensen, M.D, Bjorkling, F, Hunter, W.N.
登録日2005-09-01
公開日2006-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recombinant Human PPAR-beta/delta Ligand-binding Domain is Locked in an Activated Conformation by Endogenous Fatty Acids
J.Mol.Biol., 356, 2006
2B50
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BU of 2b50 by Molmil
Human Nuclear Receptor-Ligand Complex 2
分子名称: CALCIUM ION, Peroxisome proliferator activated receptor delta, VACCENIC ACID, ...
著者Fyffe, S.A, Alphey, M.S, Buetow, L, Smith, T.K, Ferguson, M.A.J, Sorensen, M.D, Bjorkling, F, Hunter, W.N.
登録日2005-09-27
公開日2006-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recombinant Human PPAR-beta/delta Ligand-binding Domain is Locked in an Activated Conformation by Endogenous Fatty Acids
J.Mol.Biol., 356, 2006
2BAW
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BU of 2baw by Molmil
Human Nuclear Receptor-Ligand Complex 1
分子名称: Peroxisome proliferator activated receptor delta, VACCENIC ACID, heptyl beta-D-glucopyranoside
著者Fyffe, S.A, Alphey, M.S, Buetow, L, Smith, T.K, Ferguson, M.A.J, Sorensen, M.D, Bjorkling, F, Hunter, W.N.
登録日2005-10-15
公開日2006-01-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Reevaluation of the PPAR-beta/delta Ligand Binding Domain Model Reveals Why It Exhibits the Activated Form
Mol.Cell, 21, 2006
2UZF
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BU of 2uzf by Molmil
Crystal structure of Staphylococcus aureus 1,4-dihydroxy-2-naphthoyl CoA synthase (MenB) in complex with acetoacetyl CoA
分子名称: ACETOACETYL-COENZYME A, NAPHTHOATE SYNTHASE
著者Ulaganathan, V, Buetow, L, Hunter, W.N.
登録日2007-04-27
公開日2007-11-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of Staphylococcus Aureus1,4-Dihydroxy-2-Naphthoyl-Coa Synthase (Menb) in Complex with Acetoacetyl-Coa.
Acta Crystallogr.,Sect.F, 63, 2007
6Y5N
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BU of 6y5n by Molmil
RING-DTC domain of Deltex1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase DTX1, ...
著者Gabrielsen, M, Buetow, L, Huang, D.T.
登録日2020-02-25
公開日2020-09-30
最終更新日2020-10-07
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases.
Sci Adv, 6, 2020
6Y2X
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BU of 6y2x by Molmil
RING-DTC domains of Deltex 2, Form 2
分子名称: Probable E3 ubiquitin-protein ligase DTX2, ZINC ION
著者Gabrielsen, M, Buetow, L, Huang, D.T.
登録日2020-02-17
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination.
Sci Adv, 6, 2020
6Y3J
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BU of 6y3j by Molmil
RING-DTC domains of Deltex 2, bound to ADP-ribose
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Probable E3 ubiquitin-protein ligase DTX2, ZINC ION
著者Gabrielssen, M, Buetow, L, Huang, D.T.
登録日2020-02-18
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination.
Sci Adv, 6, 2020
6Y5P
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BU of 6y5p by Molmil
RING-DTC domain of Deltex1 bound to NAD
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase DTX1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Gabrielsen, M, Buetow, L, Huang, D.T.
登録日2020-02-25
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases.
Sci Adv, 6, 2020
6Y22
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BU of 6y22 by Molmil
RING-DTC domains of Deltex 2, Form 1
分子名称: Probable E3 ubiquitin-protein ligase DTX2, ZINC ION
著者Gabrielssen, M, Buetow, L, Huang, D.T.
登録日2020-02-14
公開日2020-09-02
最終更新日2020-09-30
実験手法X-RAY DIFFRACTION (2.069 Å)
主引用文献DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination.
Sci Adv, 6, 2020
5O76
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BU of 5o76 by Molmil
Structure of phosphoY371 c-CBL in complex with ZAP70-peptide and UbV.pCBL ubiquitin variant
分子名称: CALCIUM ION, E3 ubiquitin-protein ligase CBL, Tyrosine protein kinase ZAP70 peptide, ...
著者Gabrielsen, M, Buetow, L, Huang, D.T.
登録日2017-06-08
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.473 Å)
主引用文献A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.
Mol. Cell, 68, 2017
5O6T
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BU of 5o6t by Molmil
BIRC4 RING in complex with dimeric ubiquitin variant
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase XIAP, Polyubiquitin-B, ...
著者Gabrielsen, M, Buetow, L, Huang, D.T.
登録日2017-06-07
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.
Mol. Cell, 68, 2017
5O6S
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BU of 5o6s by Molmil
UbV.B4R, a dimeric ubiquitin variant binding to BIRC4 RING
分子名称: Polyubiquitin-B
著者Gabrielsen, M, Buetow, L, Huang, D.T.
登録日2017-06-07
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.
Mol. Cell, 68, 2017
5O75
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BU of 5o75 by Molmil
Ube4B U-box domain
分子名称: SULFATE ION, Ubiquitin conjugation factor E4 B
著者Gabrielsen, M, Buetow, L, Nakasone, M.A, Huang, D.T.
登録日2017-06-08
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.483 Å)
主引用文献A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.
Mol. Cell, 68, 2017
3ZNI
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BU of 3zni by Molmil
Structure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complex
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL-B, ...
著者Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T.
登録日2013-02-14
公開日2013-07-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Essentiality of a Non-Ring Element in Priming Donor Ubiquitin for Catalysis by a Monomeric E3.
Nat.Struct.Mol.Biol., 20, 2013

 

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