5O6T

BIRC4 RING in complex with dimeric ubiquitin variant

Summary for 5O6T

Entry DOI	10.2210/pdb5o6t/pdb
Descriptor	E3 ubiquitin-protein ligase XIAP, Polyubiquitin-B, ZINC ION, ... (5 entities in total)
Functional Keywords	e3 ring ligase, ubiquitin variant, ligase
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm: P98170 Ubiquitin: Cytoplasm : P0CG47
Total number of polymer chains	4
Total formula weight	33606.43
Authors	Gabrielsen, M.,Buetow, L.,Huang, D.T. (deposition date: 2017-06-07, release date: 2017-11-01, Last modification date: 2024-01-17)
Primary citation	Gabrielsen, M.,Buetow, L.,Nakasone, M.A.,Ahmed, S.F.,Sibbet, G.J.,Smith, B.O.,Zhang, W.,Sidhu, S.S.,Huang, D.T. A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants. Mol. Cell, 68:456-470.e10, 2017 Cited by PubMed: 29053960 DOI: 10.1016/j.molcel.2017.09.027 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.57 Å)

Structure validation