5O6T

BIRC4 RING in complex with dimeric ubiquitin variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	E3 ubiquitin-protein ligase XIAP	polymer	66	7569.0	2	UniProt (P98170) Pfam (PF13920) In PDB	Homo sapiens (Human)	Baculoviral IAP repeat-containing protein 4,IAP-like protein,hILP,Inhibitor of apoptosis protein 3,hIAP3,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein,X-linked IAP
2	C, D	Polyubiquitin-B	polymer	80	9041.3	2	UniProt (P0CG47) Pfam (PF00240) In PDB	Homo sapiens (Human)
3	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4	A, B	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5		water	water		18.0	218	Chemie (HOH)

Sequence modifications

A, B: 434 - 497 (UniProt: P98170)

PDB	External Database	Details
Gly 432	-	expression tag
Ser 433	-	expression tag

C, D: -1 - 74 (UniProt: P0CG47)

PDB	External Database	Details
Ser 0	Gly 76	conflict
Leu 4	Phe 80	conflict
Thr 6	Lys 82	conflict
Ile 8	Leu 84	conflict
Ser 9	Thr 85	conflict
Ala 10	Gly 86	conflict
Glu 11	Lys 87	conflict
Arg 14	Thr 90	conflict
Phe 44	Ile 120	conflict
Glu 46	Ala 122	conflict
Asn 62	Gln 138	conflict
Lys 64	Glu 140	conflict
Leu 68	His 144	conflict
Val 71	Leu 147	conflict
Lys 72	Arg 148	conflict
Phe 73	Leu 149	conflict
His 74	Arg 150	conflict
Arg 75	-	expression tag
Val 76	-	expression tag
Ala 77	-	expression tag
Ser 78	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	33220.7
Non-Polymers*	Number of molecules	6
	Total formula weight	385.8
All*	Total formula weight	33606.4

*Water molecules are not included.