6HKW
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![BU of 6hkw by Molmil](/molmil-images/mine/6hkw) | Crystal structure of human SDS22 | Descriptor: | Protein phosphatase 1 regulatory subunit 7, SULFATE ION | Authors: | Heroes, E, Choy, M.S, Page, R, Peti, W, Ulens, C, Van Meervelt, L, Nys, M, Bollen, M. | Deposit date: | 2018-09-09 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1. Structure, 27, 2019
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4G9J
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![BU of 4g9j by Molmil](/molmil-images/mine/4g9j) | Protein Ser/Thr phosphatase-1 in complex with cell-permeable peptide | Descriptor: | MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, synthetic peptide | Authors: | Sukackaite, R, Chatterjee, J, Beullens, M, Bollen, M, Koehn, M, Hart, D.J. | Deposit date: | 2012-07-24 | Release date: | 2012-09-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells. Angew.Chem.Int.Ed.Engl., 51, 2012
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4B56
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![BU of 4b56 by Molmil](/molmil-images/mine/4b56) | Structure of ectonucleotide pyrophosphatase-phosphodiesterase-1 (NPP1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Jansen, S, Perrakis, A, Ulens, C, Winkler, C, Andries, M, Joosten, R.P, Van Acker, M, Luyten, F.P, Moolenaar, W.H, Bollen, M. | Deposit date: | 2012-08-02 | Release date: | 2012-09-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Npp1, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Involved in Tissue Calcification. Structure, 20, 2012
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6VUE
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![BU of 6vue by Molmil](/molmil-images/mine/6vue) | wild-type choline TMA lyase in complex with 1-methyl-1,2,3,6-tetrahydropyridin-3-ol | Descriptor: | (3S)-1-methyl-1,2,3,6-tetrahydropyridin-3-ol, Choline trimethylamine-lyase, SODIUM ION | Authors: | Ortega, M.A, Drennan, C.L. | Deposit date: | 2020-02-15 | Release date: | 2020-11-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. Acs Med.Chem.Lett., 11, 2020
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6ZK6
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![BU of 6zk6 by Molmil](/molmil-images/mine/6zk6) | Protein Phosphatase 1 (PP1) T320E mutant | Descriptor: | FE (III) ION, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Salvi, F, Barabas, O, Koehn, M. | Deposit date: | 2020-06-29 | Release date: | 2020-11-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation. Chembiochem, 22, 2021
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2JXW
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![BU of 2jxw by Molmil](/molmil-images/mine/2jxw) | |
3V4Y
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![BU of 3v4y by Molmil](/molmil-images/mine/3v4y) | Crystal Structure of the first Nuclear PP1 holoenzyme | Descriptor: | GLYCEROL, MANGANESE (II) ION, Nuclear inhibitor of protein phosphatase 1, ... | Authors: | Page, R, Peti, W, O'Connell, N.E, Nichols, S. | Deposit date: | 2011-12-15 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme. Structure, 20, 2012
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2XR9
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![BU of 2xr9 by Molmil](/molmil-images/mine/2xr9) | Crystal structure of Autotaxin (ENPP2) | Descriptor: | CALCIUM ION, ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, IODIDE ION, ... | Authors: | Kamtekar, S, Hausmann, J, Day, J.E, Christodoulou, E, Perrakis, A. | Deposit date: | 2010-09-13 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis of substrate discrimination and integrin binding by autotaxin. Nat. Struct. Mol. Biol., 18, 2011
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5INB
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![BU of 5inb by Molmil](/molmil-images/mine/5inb) | RepoMan-PP1g (protein phosphatase 1, gamma isoform) holoenzyme complex | Descriptor: | Cell division cycle-associated protein 2, GLYCEROL, MALONATE ION, ... | Authors: | Kumar, G.S, Peti, W, Page, R. | Deposit date: | 2016-03-07 | Release date: | 2016-10-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism. Elife, 5, 2016
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2XRG
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![BU of 2xrg by Molmil](/molmil-images/mine/2xrg) | Crystal structure of Autotaxin (ENPP2) in complex with the HA155 boronic acid inhibitor | Descriptor: | CALCIUM ION, ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, IODIDE ION, ... | Authors: | Hausmann, J, Albers, H.M.H.G, Perrakis, A. | Deposit date: | 2010-09-14 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis of Substrate Discrimination and Integrin Binding by Autotaxin. Nat.Struct.Mol.Biol., 18, 2011
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6CZO
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![BU of 6czo by Molmil](/molmil-images/mine/6czo) | The KNL1-PP1 Holoenzyme | Descriptor: | CASC5 protein, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Bajaj, R, Peti, W, Page, R. | Deposit date: | 2018-04-09 | Release date: | 2019-01-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | KNL1 Binding to PP1 and Microtubules Is Mutually Exclusive. Structure, 26, 2018
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5SWF
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![BU of 5swf by Molmil](/molmil-images/mine/5swf) | The structure of the PP2A B56 subunit double phosphorylated BubR1 complex | Descriptor: | Double phosphorylated BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | Authors: | Page, R, Wang, X, Bajaj, R, Peti, W. | Deposit date: | 2016-08-08 | Release date: | 2016-11-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.818 Å) | Cite: | Expanding the PP2A Interactome by Defining a B56-Specific SLiM. Structure, 24, 2016
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5SW9
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![BU of 5sw9 by Molmil](/molmil-images/mine/5sw9) | The structure of the PP2A B56 subunit RepoMan complex | Descriptor: | RepoMan, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | Authors: | Page, R, Wang, X, Bajaj, R, Peti, W. | Deposit date: | 2016-08-08 | Release date: | 2016-11-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.846 Å) | Cite: | Expanding the PP2A Interactome by Defining a B56-Specific SLiM. Structure, 24, 2016
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5IOH
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![BU of 5ioh by Molmil](/molmil-images/mine/5ioh) | RepoMan-PP1a (protein phosphatase 1, alpha isoform) holoenzyme complex | Descriptor: | Cell division cycle-associated protein 2, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | Authors: | Kumar, G.S, Peti, W, Page, R. | Deposit date: | 2016-03-08 | Release date: | 2016-10-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.566 Å) | Cite: | The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism. Elife, 5, 2016
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5K6S
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![BU of 5k6s by Molmil](/molmil-images/mine/5k6s) | The structure of the PP2A B56 subunit BubR1 complex | Descriptor: | BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | Authors: | Page, R, Wang, X, Bajaj, R, Peti, W. | Deposit date: | 2016-05-25 | Release date: | 2016-12-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Expanding the PP2A Interactome by Defining a B56-Specific SLiM. Structure, 24, 2016
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5J28
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![BU of 5j28 by Molmil](/molmil-images/mine/5j28) | Ki67-PP1g (protein phosphatase 1, gamma isoform) holoenzyme complex | Descriptor: | Antigen KI-67, MALONATE ION, SODIUM ION, ... | Authors: | Kumar, G.S, Peti, W, Page, R. | Deposit date: | 2016-03-29 | Release date: | 2016-10-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism. Elife, 5, 2016
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6ND3
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![BU of 6nd3 by Molmil](/molmil-images/mine/6nd3) | |