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2FFD
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BU of 2ffd by Molmil
Fibrinogen Fragment D with "A" knob peptide mimic GPRVVE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E Chain, ...
著者Betts, L.
登録日2005-12-19
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The structure of fibrinogen fragment D with the 'A' knob peptide GPRVVE.
THROMB.HAEMOST., 4, 2006
8ECR
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BU of 8ecr by Molmil
KRAS4b WT 1-185 bound to GDP-Mg2+
分子名称: GLYCEROL, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Betts, L, Rossman, K.L.
登録日2022-09-02
公開日2023-09-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献KRAS4b WT 1-185 bound to GDP-Mg2+
To Be Published
8EIE
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BU of 8eie by Molmil
KRAS4b K117N 1-185 bound to GNP-Mg2+
分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Betts, L, Rossman, K.L.
登録日2022-09-14
公開日2023-09-20
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献A crystallographic view of the fast-cycling KRAS mutant, K117N
To Be Published
8EDY
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BU of 8edy by Molmil
KRAS4b A146T 1-185 bound to GDP
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE
著者Betts, L, Rossman, K.L.
登録日2022-09-06
公開日2023-09-20
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献KRAS4b A146T 1-185 bound to GDP
To Be Published
1PNN
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BU of 1pnn by Molmil
PEPTIDE NUCLEIC ACID (PNA) COMPLEXED WITH DNA
分子名称: DNA (5'-D(GP*AP*AP*GP*AP*AP*GP*AP*G)-3'), PNA (NH2-P(*C*T*C*T*T*C*T*T*C-HIS-GLY-SER-SER-GLY-HIS-C*T*T*C*T*T*C*T*C)-COOH)
著者Betts, L, Veal, J.M.
登録日1995-10-13
公開日1996-03-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA Complex
Science, 270, 1995
4KGH
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BU of 4kgh by Molmil
Crystal Structure of human splunc1 lacking the secretion signal sequence
分子名称: AMMONIUM ION, BPI fold-containing family A member 1, GLYCEROL, ...
著者Betts, L, Walton, W.G.
登録日2013-04-29
公開日2013-09-25
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K59
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BU of 4k59 by Molmil
Crystal Structure of Pseudomonas Aeruginosa RsmF
分子名称: RNA BINDING PROTEIN RsmF
著者Betts, L, Walton, W.G, Redinbo, M.R.
登録日2013-04-14
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献An unusual CsrA family member operates in series with RsmA to amplify posttranscriptional responses in Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 110, 2013
5C7O
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BU of 5c7o by Molmil
Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+
分子名称: Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Betts, L, Machius, M, Danshina, P, O'Brien, D.
登録日2015-06-24
公開日2016-03-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.729 Å)
主引用文献Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.
Mol. Hum. Reprod., 22, 2016
5C7L
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BU of 5c7l by Molmil
Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase apo form
分子名称: Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
著者Betts, L, Machius, M, Danshina, P, O'Brien, D.
登録日2015-06-24
公開日2016-03-09
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.862 Å)
主引用文献Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.
Mol. Hum. Reprod., 22, 2016
8EER
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BU of 8eer by Molmil
KRAS4B A146V 1-185 bound to GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 4b of the GTPase KRAS
著者Betts, L, Rossman, K.L.
登録日2022-09-07
公開日2023-09-20
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献KRAS4B A146V 1-185 bound to GDP
To Be Published
2PZ1
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BU of 2pz1 by Molmil
Crystal Structure of Auto-inhibited Asef
分子名称: Rho guanine nucleotide exchange factor 4
著者Betts, L, Sondek, J, Rossman, K.L.
登録日2007-05-17
公開日2007-08-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Nat.Struct.Mol.Biol., 14, 2007
2QUO
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BU of 2quo by Molmil
Crystal Structure of C terminal fragment of Clostridium perfringens enterotoxin
分子名称: Heat-labile enterotoxin B chain, SULFATE ION
著者Betts, L, Van Itallie, C.M.
登録日2007-08-06
公開日2007-10-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of the claudin-binding domain of Clostridium perfringens enterotoxin
J.Biol.Chem., 283, 2008
3NTE
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BU of 3nte by Molmil
Crystal Structure of the Wild-type Full-Length HIV-1 Capsid Protein
分子名称: FE (III) ION, HIV-1 capsid protein, IODIDE ION, ...
著者Betts, L, Yeh, J.I.
登録日2010-07-03
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the HIV-1 full-length capsid protein in a conformationally trapped unassembled state induced by small-molecule binding.
J.Mol.Biol., 406, 2011
4HTE
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BU of 4hte by Molmil
Crystal Structure of the C-terminal domain of Nicking Enzyme from Staphylococcus aureus
分子名称: CALCIUM ION, Nicking enzyme
著者Betts, L.
登録日2012-11-01
公開日2013-01-30
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KGO
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BU of 4kgo by Molmil
Crystal Structure of double Leucine to Methionine mutant human splunc1 lacking the secretion signal sequence
分子名称: BPI fold-containing family A member 1
著者Betts, L, Walton, W.G.
登録日2013-04-29
公開日2013-09-25
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.194 Å)
主引用文献Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
Proc.Natl.Acad.Sci.USA, 110, 2013
1XO5
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BU of 1xo5 by Molmil
Crystal structure of CIB1, an EF-hand, integrin and kinase-binding protein
分子名称: CALCIUM ION, Calcium and integrin-binding protein 1
著者Gentry, H.R, Singer, A.U, Betts, L, Yang, C, Ferrara, J.D, Parise, L.V, Sondek, J.
登録日2004-10-05
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural and Biochemical Characterization of CIB1 Delineates a New Family of EF-hand-containing Proteins
J.Biol.Chem., 280, 2005
3GRE
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BU of 3gre by Molmil
Crystal structure of Saccharomyces cerevisiae Vps15 WD repeat domain
分子名称: Serine/threonine-protein kinase VPS15
著者Vanhooke, J.L, Sondek, J, Betts, L.
登録日2009-03-25
公開日2009-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and function of Vps15 in the endosomal G protein signaling pathway.
Biochemistry, 48, 2009
3BVH
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BU of 3bvh by Molmil
Crystal Structure of Recombinant gammaD364A Fibrinogen Fragment D with the Peptide Ligand Gly-Pro-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-mer peptide GPRP, CALCIUM ION, ...
著者Bowley, S.R, Merenbloom, B.K, Betts, L, Okumura, N, Heroux, A, Gorkun, O.V, Lord, S.T.
登録日2008-01-07
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic.
Biochemistry, 47, 2008
3DR9
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BU of 3dr9 by Molmil
Increased Distal Histidine Conformational Flexibility in the Deoxy Form of Dehaloperoxidase from Amphitrite ornata
分子名称: Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Chen, X, de Serrano, V.S, Betts, L, Franzen, S.
登録日2008-07-10
公開日2009-01-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Distal histidine conformational flexibility in dehaloperoxidase from Amphitrite ornata.
Acta Crystallogr.,Sect.D, 65, 2009
5C7I
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BU of 5c7i by Molmil
Mouse sperm Glyceraldehyde-3-phosphate dehydrogenase: apo enzyme
分子名称: Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
著者Danshina, P, Betts, L, O'Brien, D.
登録日2015-06-24
公開日2016-03-09
最終更新日2016-06-15
実験手法X-RAY DIFFRACTION (2.0098 Å)
主引用文献Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.
Mol. Hum. Reprod., 22, 2016
2NZ8
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BU of 2nz8 by Molmil
N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1
分子名称: ras-related C3 botulinum toxin substrate 1 isoform Rac1, triple functional domain protein
著者Chhatriwala, M.K, Betts, L, Worthylake, D.K, Sondek, J.
登録日2006-11-22
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation
J.Mol.Biol., 368, 2007
1KJY
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BU of 1kjy by Molmil
Crystal Structure of Human G[alpha]i1 Bound to the GoLoco Motif of RGS14
分子名称: CESIUM ION, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT, ...
著者Kimple, R.J, Kimple, M.E, Betts, L, Sondek, J, Siderovski, D.P.
登録日2001-12-05
公開日2002-05-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits.
Nature, 416, 2002
1LB1
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BU of 1lb1 by Molmil
Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA
分子名称: Guanine nucleotide exchange factor DBS, Transforming protein RhoA
著者Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J.
登録日2002-04-01
公開日2002-05-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
1LTJ
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BU of 1ltj by Molmil
Crystal Structure of Recombinant Human Fibrinogen Fragment D with the Peptide Ligands Gly-Pro-Arg-Pro-Amide and Gly-His-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen Beta chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2002-05-20
公開日2002-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Biochemistry, 41, 2002
1LT9
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BU of 1lt9 by Molmil
Crystal Structure of Recombinant Human Fibrinogen Fragment D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2002-05-20
公開日2002-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Biochemistry, 41, 2002

 

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