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6B3S
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BU of 6b3s by Molmil
Crystal structure of the Fab fragment of necitumumab (Fab11F8) in complex with domain III from a cetuximab resistant variant of EGFR (sEGFRd3-S468R)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Ferguson, K.M, Bagchi, A.
Deposit date:2017-09-23
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Basis for Necitumumab Inhibition of EGFR Variants Associated with Acquired Cetuximab Resistance.
Mol. Cancer Ther., 17, 2018
8UKV
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BU of 8ukv by Molmil
Crystal structure of nanobody/VHH domain of 34E5 in complex with the extracellular region of the epidermal growth factor variant III (EGFRvIII)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Stayrook, S.E, Ferguson, K.M, Bagchi, A.
Deposit date:2023-10-15
Release date:2024-06-19
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Structural insights into the role and targeting of EGFRvIII.
Structure, 2024
8UKW
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BU of 8ukw by Molmil
Crystal structure the extracellular region of the epidermal growth factor receptor variant III (EGFRvIII) at pH 5.0
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Stayrook, S.E, Ferguson, K.M.
Deposit date:2023-10-15
Release date:2024-06-12
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural insights into the role and targeting of EGFRvIII.
Structure, 2024
8UKX
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BU of 8ukx by Molmil
Crystal structure the extracellular region of the epidermal growth factor receptor variant III (EGFRvIII) at pH 7.0
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Stayrook, S.E, Ferguson, K.M.
Deposit date:2023-10-15
Release date:2024-06-12
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structural insights into the role and targeting of EGFRvIII.
Structure, 2024
4KRP
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BU of 4krp by Molmil
Nanobody/VHH domain 9G8 in complex with the extracellular region of EGFR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab heavy chain, ...
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.823 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4KRL
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BU of 4krl by Molmil
Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 6.0
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4KRM
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BU of 4krm by Molmil
Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 3.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.655 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4KRO
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BU of 4kro by Molmil
Nanobody/VHH domain EgA1 in complex with the extracellular region of EGFR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab heavy chain, ...
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.054 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4KRN
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BU of 4krn by Molmil
Nanobody/VHH domain EgA1
Descriptor: Nanobody/VHH domain EgA1, SULFATE ION
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.553 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013

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PDB entries from 2024-07-17

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