7YCI
 
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the first-step self-splicing | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (389-MER), ... | | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | Deposit date: | 2022-07-01 | | Release date: | 2023-07-05 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YC8
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 1 undergoing the first-step self-splicing | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA (388-MER) | | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | Deposit date: | 2022-07-01 | | Release date: | 2023-07-05 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (4.14 Å) | | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YGA
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 2 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (393-MER), RNA (5'-R(*CP*CP*CP*UP*CP*U)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (2.35 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YG8
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 5 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (387-MER), RNA (5'-R(*CP*CP*CP*UP*C)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YGD
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 6 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (384-MER), RNA (5'-R(*CP*C)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YGC
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (393-MER), RNA (5'-R(*CP*CP*CP*UP*CP*UP*UP*AP*AP*CP*C)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YGB
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (393-MER), RNA (5'-R(*CP*CP*CP*UP*CP*UP*UP*AP*AP*CP*C)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YG9
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 1 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (391-MER), RNA (5'-R(*CP*CP*CP*UP*CP*U)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7XDT
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7XGR
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8J72
 | | Crystal structure of mammalian Trim71 in complex with lncRNA Trincr1 | | Descriptor: | E3 ubiquitin-protein ligase TRIM71, lncRNA Trincr1 | | Authors: | Shi, F.D, Zhang, K, Che, S.Y, Zhi, S.X, Yang, N. | | Deposit date: | 2023-04-27 | | Release date: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.16 Å) | | Cite: | Molecular mechanism governing RNA-binding property of mammalian TRIM71 protein.
Sci Bull (Beijing), 69, 2024
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8K3Y
 | | The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | Authors: | Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I. | | Deposit date: | 2023-07-17 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (4.42 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YHN
 | | ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Du, T, Ji, M, Hou, Z, Lin, S, Zhang, J, Wu, D, Zhang, K, Lu, D, Xu, H, Chen, X. | | Deposit date: | 2022-07-14 | | Release date: | 2023-07-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site.
J.Med.Chem., 65, 2022
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7VFP
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with heme and single ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | Deposit date: | 2021-09-13 | | Release date: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (4.03 Å) | | Cite: | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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7VFJ
 | | Cytochrome c-type biogenesis protein CcmABCD | | Descriptor: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | | Authors: | Zhu, J.P, Zhang, K, Li, J, Zheng, W, Gu, M. | | Deposit date: | 2021-09-13 | | Release date: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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7EZ2
 | | Holo L-16 ScaI Tetrahymena ribozyme | | Descriptor: | Holo L-16 ScaI Tetrahymena ribozyme, Holo L-16 ScaI Tetrahymena ribozyme S1, Holo L-16 ScaI Tetrahymena ribozyme S2, ... | | Authors: | Su, Z, Zhang, K, Kappel, K, Luo, B, Das, R, Chiu, W. | | Deposit date: | 2021-06-01 | | Release date: | 2021-08-25 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 angstrom resolution.
Nature, 596, 2021
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7EZ0
 | | Apo L-21 ScaI Tetrahymena ribozyme | | Descriptor: | Apo L-21 ScaI Tetrahymena ribozyme, MAGNESIUM ION | | Authors: | Su, Z, Zhang, K, Kappel, K, Luo, B, Das, R, Chiu, W. | | Deposit date: | 2021-06-01 | | Release date: | 2021-08-25 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 angstrom resolution.
Nature, 596, 2021
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7FD5
 | | A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | | Deposit date: | 2021-07-16 | | Release date: | 2021-11-03 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
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7FD4
 | | A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | | Deposit date: | 2021-07-16 | | Release date: | 2021-11-03 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
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7FIE
 | | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 2) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | | Deposit date: | 2021-07-31 | | Release date: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (2.36 Å) | | Cite: | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
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7FIZ
 | | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 3) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | | Deposit date: | 2021-08-01 | | Release date: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
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7FID
 | | Processive cleavage of substrate at individual proteolytic active sites of the Lon proteasecomplex (conformation 1) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | | Deposit date: | 2021-07-31 | | Release date: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (2.44 Å) | | Cite: | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
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7EVP
 | | Cryo-EM structure of the Gp168-beta-clamp complex | | Descriptor: | Beta sliding clamp, Sliding clamp inhibitor | | Authors: | Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K. | | Deposit date: | 2021-05-21 | | Release date: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel.
Nucleic Acids Res., 49, 2021
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7F02
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | Deposit date: | 2021-06-03 | | Release date: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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7F04
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ... | | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | Deposit date: | 2021-06-03 | | Release date: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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