6LBN
 
 | | Structure of SIL1-bound FEM1C | | Descriptor: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-14 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.899 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LEY
 | | Structure of Sil1G bound FEM1C | | Descriptor: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-27 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6MCP
 | | L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A | | Descriptor: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | | Authors: | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | | Deposit date: | 2018-09-01 | | Release date: | 2019-09-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6MCQ
 | | L. pneumophila effector kinase LegK7 in complex with human MOB1A | | Descriptor: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | | Authors: | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | | Deposit date: | 2018-09-01 | | Release date: | 2019-09-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6K99
 | | Structure of ASC CARD filament | | Descriptor: | Apoptosis-associated speck-like protein containing a CARD | | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | | Deposit date: | 2019-06-14 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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7D1L
 | | complex structure of two RRM domains | | Descriptor: | Embryonic developmental protein tofu-6, Uncharacterized protein | | Authors: | Wang, X, Liao, S, Xu, C. | | Deposit date: | 2020-09-14 | | Release date: | 2021-08-25 | | Last modified: | 2021-10-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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7D2Y
 | | complex of two RRM domains | | Descriptor: | Embryonic developmental protein tofu-6, RRM2, SULFATE ION | | Authors: | Wang, X, Liao, S, Xu, C. | | Deposit date: | 2020-09-17 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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7EJS
 | | Structure of ERH-2 bound to PICS-1 | | Descriptor: | Enhancer of rudimentary homolog 2,Protein pid-3 | | Authors: | Wang, X, Xu, C. | | Deposit date: | 2021-04-02 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.387 Å) | | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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7EJO
 | | Structure of ERH-2 bound to TOST-1 | | Descriptor: | Enhancer of rudimentary homolog 2, Enhancer of rudimentary homolog 2,Protein tost-1 | | Authors: | Wang, X, Xu, C. | | Deposit date: | 2021-04-02 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.191 Å) | | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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7XGR
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7XDT
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7X39
 | | Structure of CIZ1 bound ERH | | Descriptor: | Enhancer of rudimentary homolog,Cip1-interacting zinc finger protein | | Authors: | Wang, X, Xu, C. | | Deposit date: | 2022-02-28 | | Release date: | 2022-08-31 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Molecular basis for the recognition of CIZ1 by ERH.
Febs J., 290, 2023
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7U8K
 | | Magic Angle Spinning NMR Structure of Human Cofilin-2 Assembled on Actin Filaments | | Descriptor: | Actin, alpha skeletal muscle, Cofilin-2 | | Authors: | Kraus, J, Russell, R, Kudryashova, E, Xu, C, Katyal, N, Kudryashov, D, Perilla, J.R, Polenova, T. | | Deposit date: | 2022-03-08 | | Release date: | 2023-08-16 | | Last modified: | 2024-02-28 | | Method: | SOLID-STATE NMR | | Cite: | Magic angle spinning NMR structure of human cofilin-2 assembled on actin filaments reveals isoform-specific conformation and binding mode.
Nat Commun, 13, 2022
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7DRW
 | | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | | Descriptor: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | | Authors: | Cong, Y, Xu, C. | | Deposit date: | 2020-12-29 | | Release date: | 2021-01-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Cryo-EM of mammalian PA28 alpha beta-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28 alpha beta.
Nat Commun, 12, 2021
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7DR6
 | | PA28alpha-beta in complex with immunoproteasome | | Descriptor: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | | Authors: | Cong, Y, Xu, C. | | Deposit date: | 2020-12-26 | | Release date: | 2021-01-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Cryo-EM of mammalian PA28 alpha beta-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28 alpha beta.
Nat Commun, 12, 2021
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7VU8
 | | L7-Tir domain with bound ligand | | Descriptor: | 2',3'- cyclic AMP, Flax rust resistance protein | | Authors: | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | | Deposit date: | 2021-11-01 | | Release date: | 2022-06-01 | | Last modified: | 2022-07-06 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.
Cell, 185, 2022
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7X5L
 | | Tir-dsDNA complex, the initial binding state | | Descriptor: | DNA (5'-D(*AP*TP*AP*AP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*AP*TP*TP*AP*A)-3'), Flax rust resistance protein | | Authors: | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | | Deposit date: | 2022-03-04 | | Release date: | 2022-06-01 | | Last modified: | 2022-07-06 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.
Cell, 185, 2022
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7X5M
 | | Tir-dsDNA complex, the initial binding state | | Descriptor: | 2',3'- cyclic AMP, DNA (5'-D(P*AP*TP*TP*AP*A)-3'), DNA (5'-D(P*AP*TP*TP*TP*A)-3'), ... | | Authors: | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | | Deposit date: | 2022-03-05 | | Release date: | 2022-06-01 | | Last modified: | 2022-07-06 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.
Cell, 185, 2022
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7X5K
 | | Tir-dsDNA complex, the initial binding state | | Descriptor: | DNA (43-MER), Flax rust resistance protein | | Authors: | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | | Deposit date: | 2022-03-04 | | Release date: | 2022-06-08 | | Last modified: | 2022-07-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.
Cell, 185, 2022
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7ESE
 | | The Crystal Structure of human DHFR from Biortus | | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Wang, F, Cheng, W, Xu, C, Qi, J, Bao, X, Miao, Q. | | Deposit date: | 2021-05-10 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Crystal Structure of human DHFR from Biortus
To Be Published
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7EL6
 | | Structure of SMCR8 bound FEM1B | | Descriptor: | Protein fem-1 homolog B,Guanine nucleotide exchange protein SMCR8 | | Authors: | Zhao, S, Xu, C. | | Deposit date: | 2021-04-08 | | Release date: | 2021-05-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.802 Å) | | Cite: | Structural insights into SMCR8 C-degron recognition by FEM1B.
Biochem.Biophys.Res.Commun., 557, 2021
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7CXZ
 | | crystal structure of pco2 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, NICKEL (II) ION, ... | | Authors: | Guo, Q, Xu, C, Liao, S, Chen, Z. | | Deposit date: | 2020-09-02 | | Release date: | 2020-11-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.561 Å) | | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
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7E9W
 | | The Crystal Structure of D-psicose-3-epimerase from Biortus. | | Descriptor: | D-psicose 3-epimerase, GLYCEROL, MANGANESE (II) ION | | Authors: | Wang, F, Xu, C, Qi, J, Zhang, M, Tian, F, Wang, M. | | Deposit date: | 2021-03-05 | | Release date: | 2021-03-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Crystal Structure of D-psicose-3-epimerase from Biortus.
To Be Published
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7DH6
 | | Crystal structure of PLRG1 | | Descriptor: | CALCIUM ION, NICKEL (II) ION, Pleiotropic regulator 1, ... | | Authors: | Wang, X, Xu, C. | | Deposit date: | 2020-11-13 | | Release date: | 2020-12-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.584 Å) | | Cite: | Crystal structure of the WD40 domain of human PLRG1.
Biochem.Biophys.Res.Commun., 534, 2021
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7CHI
 | | crystal structure of pco5 | | Descriptor: | FE (III) ION, Plant cysteine oxidase 5 | | Authors: | Guo, Q, Xu, C, Liao, S. | | Deposit date: | 2020-07-05 | | Release date: | 2020-11-25 | | Last modified: | 2021-03-31 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
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