7X5M

Tir-dsDNA complex, the initial binding state

Summary for 7X5M

• Entry DOI: 10.2210/pdb7x5m/pdb
• EMDB information: 32126
• Descriptor: DNA (5'-D(P*AP*TP*TP*AP*A)-3'), DNA (5'-D(P*AP*TP*TP*TP*A)-3'), Flax rust resistance protein, ... (4 entities in total)
• Functional Keywords: plant innate immune receptor, nucleic acids, 2', 3'cnmp, hydrolase-dna complex, hydrolase/dna
• Biological source: DNA molecule; More
• Total number of polymer chains: 4
• Total formula weight: 50720.18

Authors

Tan, Y.,Xu, C.,Yu, D.,Song, W.,Wu, B.,Schulze-Lefert, P.,Chai, J. (deposition date: 2022-03-05, release date: 2022-06-01, Last modification date: 2022-07-06)

• Primary citation: Yu, D.,Song, W.,Tan, E.Y.J.,Liu, L.,Cao, Y.,Jirschitzka, J.,Li, E.,Logemann, E.,Xu, C.,Huang, S.,Jia, A.,Chang, X.,Han, Z.,Wu, B.,Schulze-Lefert, P.,Chai, J.; TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.; Cell, 185:2370-2386.e18, 2022; PubMed: 35597242; DOI: 10.1016/j.cell.2022.04.032

Experimental method

ELECTRON MICROSCOPY (3.42 Å)