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4Q2E
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BU of 4q2e by Molmil
CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S258C, active mutant)
Descriptor: MAGNESIUM ION, MERCURY (II) ION, POTASSIUM ION, ...
Authors:Liu, X, Yin, Y, Wu, J, Liu, Z.
Deposit date:2014-04-08
Release date:2014-07-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and mechanism of an intramembrane liponucleotide synthetase central for phospholipid biosynthesis
Nat Commun, 5, 2014
4R7A
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BU of 4r7a by Molmil
Crystal Structure of RBBP4 bound to PHF6 peptide
Descriptor: GLYCEROL, Histone-binding protein RBBP4, PHD finger protein 6
Authors:Liu, Z, Li, F, Zhang, B, Li, S, Wu, J, Shi, Y.
Deposit date:2014-08-27
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of Plant Homeodomain Finger 6 (PHF6) Recognition by the Retinoblastoma Binding Protein 4 (RBBP4) Component of the Nucleosome Remodeling and Deacetylase (NuRD) Complex
J.Biol.Chem., 290, 2015
5SYO
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BU of 5syo by Molmil
Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with Cytisine
Descriptor: (1R,5S)-1,2,3,4,5,6-HEXAHYDRO-8H-1,5-METHANOPYRIDO[1,2-A][1,5]DIAZOCIN-8-ONE, Soluble acetylcholine receptor, Neuronal acetylcholine receptor subunit alpha-3 chimera
Authors:Bobango, J, Wu, J, Talley, I.T, Talley, T.T.
Deposit date:2016-08-11
Release date:2016-10-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with Cytisine
To Be Published
5TVC
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BU of 5tvc by Molmil
Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312)
Descriptor: (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine, PENTAETHYLENE GLYCOL, SULFATE ION, ...
Authors:Bobango, J, Wu, J, Talley, I.T, Talley, T.T.
Deposit date:2016-11-08
Release date:2016-11-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.926 Å)
Cite:Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312)
To Be Published
7WTD
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BU of 7wtd by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ...
Authors:Chai, P, Lan, P, Wu, J, Lei, M.
Deposit date:2022-02-04
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTE
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BU of 7wte by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2
Descriptor: ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ...
Authors:Chai, P, Lan, P, Wu, J, Lei, M.
Deposit date:2022-02-04
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTA
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BU of 7wta by Molmil
Cryo-EM structure of human pyruvate carboxylase in apo state
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial
Authors:Chai, P, Lan, P, Wu, J, Lei, M.
Deposit date:2022-02-04
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTC
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BU of 7wtc by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ...
Authors:Chai, P, Lan, P, Wu, J, Lei, M.
Deposit date:2022-02-04
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTB
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BU of 7wtb by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chai, P, Lan, P, Wu, J, Lei, M.
Deposit date:2022-02-04
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7C7A
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BU of 7c7a by Molmil
Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1
Descriptor: Internal Transcribed Spacer 1, MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, ...
Authors:Lan, P, Wu, J, Lei, M.
Deposit date:2020-05-24
Release date:2020-07-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Science, 369, 2020
7C79
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BU of 7c79 by Molmil
Cryo-EM structure of yeast Ribonuclease MRP
Descriptor: MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease MRP RNA subunit NME1, ...
Authors:Lan, P, Wu, J, Lei, M.
Deposit date:2020-05-24
Release date:2020-07-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Science, 369, 2020
5T0I
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BU of 5t0i by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0C
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BU of 5t0c by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2016-08-15
Release date:2016-10-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0J
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BU of 5t0j by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0G
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BU of 5t0g by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0H
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BU of 5t0h by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5FFM
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BU of 5ffm by Molmil
Yellow fever virus helicase
Descriptor: Serine protease NS3
Authors:Smith, J.L.
Deposit date:2015-12-18
Release date:2015-12-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing.
J. Virol., 79, 2005
6OZH
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BU of 6ozh by Molmil
Crystal structure of Ciona intestinalis (Ci) Endonuclease V in complex with a 24mer DNA containing an inosine followed by a ribo-adenosine
Descriptor: CALCIUM ION, DNA/RNA (5'-D(P*CP*GP*GP*TP*AP*AP*CP*CP*GP*I)-R(P*A)-D(P*TP*AP*TP*GP*CP*AP*GP*CP*AP*TP*TP*TP*C)-3'), endonuclease V isoform X2
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.026 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZJ
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BU of 6ozj by Molmil
Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine in the absence of divalent cation
Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.247 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZQ
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BU of 6ozq by Molmil
Crystal structure of Mus musculus (Mm) Endonuclease V (K155M) in complex with a 23mer RNA oligo containing an inosine after a 100 min soak in 10 mM Mn2+ and K+
Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.153 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZP
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BU of 6ozp by Molmil
Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 180 min soak in 10 mM Mn2+
Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*A)-3'), Endonuclease V, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZE
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BU of 6oze by Molmil
Crystal structure of the catalytic domain of human Endonuclease V (C140S/C225S/C226A/C228S)
Descriptor: ACETATE ION, Endonuclease V, GLYCEROL, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZI
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BU of 6ozi by Molmil
Crystal structure of Ciona intestinalis (Ci) Endonuclease V (D234N) in complex with a 23mer DNA containing an inosine followed by a ribo-adenosine
Descriptor: DNA/RNA (23-MER), POTASSIUM ION, TRIETHYLENE GLYCOL, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZS
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BU of 6ozs by Molmil
Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 90 min soak in 10 mM Mg2+
Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*A)-3'), Endonuclease V, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZL
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BU of 6ozl by Molmil
Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 2 min soak in Mn2+
Descriptor: DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, GLYCEROL, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019

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