5TVC

Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312)

Summary for 5TVC

• Entry DOI: 10.2210/pdb5tvc/pdb
• Descriptor: Soluble acetylcholine receptor,Neuronal acetylcholine receptor subunit alpha-3 chimera, SULFATE ION, PENTAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: nicotinic, acetylcholine, achbp, chimeric protein, acetylcholine-binding protein
• Biological source: Aplysia californica (California sea hare); More
• Total number of polymer chains: 5
• Total formula weight: 133464.50

Authors

Bobango, J.,Wu, J.,Talley, I.T.,Talley, T.T. (deposition date: 2016-11-08, release date: 2016-11-30, Last modification date: 2023-10-04)

• Primary citation: Bobango, J.,Wu, J.,Talley, I.T.,Talley, T.T.; Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.926 Å)