5TVC
Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312)
Summary for 5TVC
Entry DOI | 10.2210/pdb5tvc/pdb |
Descriptor | Soluble acetylcholine receptor,Neuronal acetylcholine receptor subunit alpha-3 chimera, SULFATE ION, PENTAETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | nicotinic, acetylcholine, achbp, chimeric protein, acetylcholine-binding protein |
Biological source | Aplysia californica (California sea hare) More |
Total number of polymer chains | 5 |
Total formula weight | 133464.50 |
Authors | Bobango, J.,Wu, J.,Talley, I.T.,Talley, T.T. (deposition date: 2016-11-08, release date: 2016-11-30, Last modification date: 2023-10-04) |
Primary citation | Bobango, J.,Wu, J.,Talley, I.T.,Talley, T.T. Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.926 Å) |
Structure validation
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