6OZL

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 2 min soak in Mn2+

Summary for 6OZL

DescriptorEndonuclease V, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), MANGANESE (II) ION, ... (8 entities in total)
Functional Keywordsnucleic acid hydrolysis, rna recognition, metal ion dependent catalysis, dna damage, adenosine deamination, hydrolase
Biological sourceMus musculus (Mouse)
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Total number of polymer chains4
Total molecular weight71561.04
Authors
Samara, N.L.,Yang, W. (deposition date: 2019-05-15, release date: 2019-09-04, Last modification date: 2019-10-16)
Primary citation
Wu, J.,Samara, N.L.,Kuraoka, I.,Yang, W.
Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76:44-, 2019
PubMed: 31444105 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2019.06.046
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21640 1.7% 6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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