Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 2 min soak in Mn2+

Summary for 6OZL

DescriptorEndonuclease V, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), MANGANESE (II) ION, ... (8 entities in total)
Functional Keywordsnucleic acid hydrolysis, rna recognition, metal ion dependent catalysis, dna damage, adenosine deamination, hydrolase
Biological sourceMus musculus (Mouse)
Total number of polymer chains4
Total molecular weight71561.04
Samara, N.L.,Yang, W. (deposition date: 2019-05-15, release date: 2019-09-04, Last modification date: 2019-10-16)
Primary citation
Wu, J.,Samara, N.L.,Kuraoka, I.,Yang, W.
Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76:44-, 2019
PubMed: 31444105 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2019.06.046
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21640 1.7% 6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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