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2L4C
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BU of 2l4c by Molmil
Solution Structure of the b domain of Human ERp27
分子名称: Endoplasmic reticulum resident protein 27
著者Amin, N.T, Wallis, K, Rowe, M.L, Kelly, G, Frenkiel, T.A, Williamson, R.A, Howard, M.J, Freedman, R.B.
登録日2010-10-03
公開日2010-11-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the b domain of human ERp27
To be Published
2TMP
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BU of 2tmp by Molmil
N-TERMINAL DOMAIN OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 (N-TIMP-2), NMR, 49 STRUCTURES
分子名称: TISSUE INHIBITOR OF METALLOPROTEINASES-2
著者Muskett, F.W, Frenkiel, T.A, Feeney, J, Freedman, R.B, Carr, M.D, Williamson, R.A.
登録日1998-05-26
公開日1998-12-09
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3.
J.Biol.Chem., 273, 1998
2K8V
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BU of 2k8v by Molmil
Solution structure of Oxidised ERp18
分子名称: Thioredoxin domain-containing protein 12
著者Rowe, M.L, Alanen, H.I, Ruddock, L.W, Kelly, G, Schmidt, J.M, Williamson, R.A, Howard, M.J.
登録日2008-09-25
公開日2009-06-02
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of ERp18, a small endoplasmic reticulum resident oxidoreductase .
Biochemistry, 48, 2009
1NYO
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BU of 1nyo by Molmil
Solution structure of the antigenic TB protein MPT70/MPB70
分子名称: Immunogenic protein MPT70
著者Bloemink, M.J, Dentten, E, Hewinson, R.G, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC)
登録日2003-02-13
公開日2003-08-19
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease
J.Biol.Chem., 278, 2003
1WA8
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BU of 1wa8 by Molmil
Solution Structure of the CFP-10.ESAT-6 Complex. Major Virulence Determinants of Pathogenic Mycobacteria
分子名称: 6 KDA EARLY SECRETORY ANTIGENIC TARGET (ESAT-6), ESAT-6 LIKE PROTEIN ESXB
著者Renshaw, P.S, Lightbody, K.L, Veverka, V, Muskett, F.W, Kelly, G, Frenkiel, T.A, Gordon, S.V, Hewinson, R.G, Burke, B, Norman, J, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC)
登録日2004-10-25
公開日2005-06-27
最終更新日2019-08-21
実験手法SOLUTION NMR
主引用文献Structure and Function of the Complex Formed by the Tuberculosis Virulence Factors Cfp-10 and Esat-6
Embo J., 24, 2005
1CU4
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BU of 1cu4 by Molmil
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN, RECOGNITION PEPTIDE
著者Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E.
登録日1999-08-20
公開日2000-04-17
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
1CR9
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BU of 1cr9 by Molmil
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4
分子名称: FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN
著者Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E.
登録日1999-08-14
公開日2000-04-17
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
3BJ5
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BU of 3bj5 by Molmil
Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain
分子名称: Protein disulfide-isomerase, SULFATE ION
著者Ruddock, L.W, Nguyen, V.D, Wierenga, R.K, Haapalainen, A.M.
登録日2007-12-03
公開日2008-09-30
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain
J.Mol.Biol., 383, 2008
2HH0
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BU of 2hh0 by Molmil
Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope.
分子名称: Heavy Chain, P-Clone Fab, Chimera, ...
著者Kanyo, Z.K.
登録日2006-06-27
公開日2006-12-26
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation
J.Mol.Biol., 363, 2006
6BLI
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BU of 6bli by Molmil
RSV G peptide bound to Fab CB002.5
分子名称: CB002.5 Fab Heavy Chain, CB002.5 Fab Light Chain, Major surface glycoprotein G
著者Jones, H.G, McLellan, J.S, Langedijk, J.P.
登録日2017-11-10
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
6BLH
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BU of 6blh by Molmil
RSV G central conserved region bound to Fab CB017.5
分子名称: 1,2-ETHANEDIOL, Fab CB017.5 heavy chain, Fab CB017.5 light chain, ...
著者Jones, H.G, McLellan, J.S, Langedijk, J.P.
登録日2017-11-10
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
4AWI
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BU of 4awi by Molmil
Human Jnk1alpha kinase with 4-phenyl-7-azaindole IKK2 inhibitor.
分子名称: MITOGEN-ACTIVATED PROTEIN KINASE 8, N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-4-[2-(1-methylethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamide, SULFATE ION
著者Chung, C, Vicentini, G, Liddle, J, Bamborough, P.
登録日2012-06-03
公開日2013-05-01
最終更新日2014-07-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献4-Phenyl-7-Azaindoles as Potent, Selective and Bioavailable Ikk2 Inhibitors Demonstrating Good in Vivo Efficacy.
Bioorg.Med.Chem.Lett., 22, 2012

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