3BJ5

Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain

Summary for 3BJ5

Entry DOI	10.2210/pdb3bj5/pdb
Descriptor	Protein disulfide-isomerase, SULFATE ION (3 entities in total)
Functional Keywords	thioredoxin fold, chaperone, endoplasmic reticulum, isomerase, membrane, redox-active center
Biological source	Homo sapiens (Human)
Cellular location	Endoplasmic reticulum lumen: P07237
Total number of polymer chains	1
Total formula weight	17366.84
Authors	Ruddock, L.W.,Nguyen, V.D.,Wierenga, R.K.,Haapalainen, A.M. (deposition date: 2007-12-03, release date: 2008-09-30, Last modification date: 2021-11-10)
Primary citation	Nguyen, V.D.,Wallis, K.,Howard, M.J.,Haapalainen, A.M.,Salo, K.E.H.,Saaranen, M.J.,Sidhu, A.,Wierenga, R.K.,Freedman, R.B.,Ruddock, L.W.,Williamson, R.A. Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain J.Mol.Biol., 383:1144-1155, 2008 Cited by PubMed: 18801374 DOI: 10.1016/j.jmb.2008.08.085 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation