3BJ5

Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein disulfide-isomerase	polymer	147	17270.8	1	UniProt (P07237) Pfam (PF13848) In PDB	Homo sapiens (Human)	PDI, Prolyl 4-hydroxylase subunit beta, Cellular thyroid hormone-binding protein, p55
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3		water	water		18.0	45	Chemie (HOH)

Sequence modifications

A: 213 - 351 (UniProt: P07237)

PDB	External Database	Details
Met 205	-	initiating methionine
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
Met 212	-	expression tag
Ala 272	Ile 289	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17270.8
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	17366.8

*Water molecules are not included.