4F3O
| DNA Polymerase I Large Fragment Complex 5 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*GP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-09 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4F8R
| Bacillus DNA Polymerase I Large Fragment complex 7 | Descriptor: | DNA (5'-D(*CP*AP*TP*TP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3'), DNA polymerase, ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-17 | Release date: | 2013-08-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4EZ6
| Bacillus DNA Polymerase I Large Fragment Complex 1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-02 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4F4K
| DNA Polymerase I Large Fragment Complex 6 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-10 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4F2R
| DNA Polymerase I Large Fragment complex 3 | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-08 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
3PX0
| |
3PV8
| |
3PX6
| |
3PS5
| Crystal structure of the full-length Human Protein Tyrosine Phosphatase SHP-1 | Descriptor: | SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6 | Authors: | Wang, W, Liu, L, Song, X, Mo, Y, Komma, C, Bellamy, H.D, Zhao, Z.J, Zhou, G.W. | Deposit date: | 2010-11-30 | Release date: | 2011-04-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of human protein tyrosine phosphatase SHP-1 in the open conformation. J.Cell.Biochem., 112, 2011
|
|
3PX4
| |
7TO1
| Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+ATP) | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30 | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
|
|
7TNY
| Cryo-EM structure of RIG-I in complex with p2dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
|
|
7TO2
| |
7TO0
| Cryo-EM structure of RIG-I in complex with OHdsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, OHdsRNA, ZINC ION | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
|
|
7TNZ
| Cryo-EM structure of RIG-I in complex with p1dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p1dsRNA | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
|
|
7TNX
| Cryo-EM structure of RIG-I in complex with p3dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3dsRNAa, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
|
|
8G7T
| Cryo-EM structure of RNP end | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2023-02-17 | Release date: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) To Be Published
|
|
8G7U
| Cryo-EM structure of RNP end 2 | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2023-02-17 | Release date: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) To Be Published
|
|
8G7V
| Cryo-EM structure of RNP inter | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2023-02-17 | Release date: | 2023-11-15 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) To Be Published
|
|
5XGQ
| |
5XET
| Crystal structure of Mycobacterium tuberculosis methionyl-tRNA synthetase bound by methionyl-adenylate (Met-AMP) | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Methionine--tRNA ligase, ... | Authors: | Wang, W, Qin, B, Wojdyla, J.A, Wang, M, Gao, X, Cui, S. | Deposit date: | 2017-04-06 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism. IUCrJ, 5, 2018
|
|
5Z1Q
| Crystal structures of the trimeric N-terminal domain of Ciliate Euplotes octocarinatus Centrin | Descriptor: | CALCIUM ION, CHLORIDE ION, Centrin protein | Authors: | Wang, W, Zhao, Y, Yang, B, Wang, H. | Deposit date: | 2017-12-27 | Release date: | 2018-04-25 | Last modified: | 2018-06-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the trimeric N-terminal domain of ciliate Euplotes octocarinatus centrin binding with calcium ions Protein Sci., 27, 2018
|
|
6BLP
| Pol II elongation complex with an abasic lesion at i+1 position, soaking AMPCPP | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(P*AP*(3DR)P*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, W, Wang, D. | Deposit date: | 2017-11-11 | Release date: | 2018-02-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.203 Å) | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6BM2
| Pol II elongation complex with an abasic lesion at i-1 position | Descriptor: | DNA (5'-D(P*CP*AP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | Authors: | Wang, W, Wang, D. | Deposit date: | 2017-11-13 | Release date: | 2018-02-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.403 Å) | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6BM4
| Pol II elongation complex with an abasic lesion at i-1 position,soaking UMPNPP | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DNA (5'-D(P*CP*AP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, W, Wang, D. | Deposit date: | 2017-11-13 | Release date: | 2018-02-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.951 Å) | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|