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2V77
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BU of 2v77 by Molmil
Crystal Structure of Human Carboxypeptidase A1
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CARBOXYPEPTIDASE A1, OCTANE-1,3,5,7-TETRACARBOXYLIC ACID, ...
Authors:Pallares, I, Fernandez, D, Comellas-Bigler, M, Fernandez-Recio, J, Ventura, S, Aviles, F.X, Vendrell, J.
Deposit date:2007-07-27
Release date:2008-07-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid).
Acta Crystallogr. D Biol. Crystallogr., D64, 2008
6FXU
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BU of 6fxu by Molmil
Crystal structure of human transthyretin mutant T119M at pH 5.5
Descriptor: Transthyretin
Authors:Varejao, N, Esperante, S, Ventura, S, Reverter, D.
Deposit date:2018-03-09
Release date:2019-03-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.359 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
6FZL
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BU of 6fzl by Molmil
Crystal structure of human transthyretin double mutant K35T/T119M
Descriptor: Transthyretin
Authors:Esperante, S, Ventura, S, Reverter, D, Varejao, N.
Deposit date:2018-03-15
Release date:2019-03-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.446 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
5FW8
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BU of 5fw8 by Molmil
Structure of human transthyretin mutant E89K
Descriptor: TRANSTHYRETIN
Authors:Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
5FW7
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BU of 5fw7 by Molmil
Structure of human transthyretin mutant A109V
Descriptor: TRANSTHYRETIN
Authors:Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2017-03-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
1ZFI
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BU of 1zfi by Molmil
Solution structure of the leech carboxypeptidase inhibitor
Descriptor: Metallocarboxypeptidase inhibitor
Authors:Arolas, J.L, D'Silva, L, Popowicz, G.M, Aviles, F.X, Holak, T.A, Ventura, S.
Deposit date:2005-04-20
Release date:2005-09-13
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
4D7B
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BU of 4d7b by Molmil
Structure of human transthyretin in complex with Tolcapone
Descriptor: TRANSTHYRETIN, Tolcapone
Authors:Gallego, P, Sant'anna, R.O, Ventura, S, Reverter, D.
Deposit date:2014-11-21
Release date:2016-01-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Repositioning Tolcapone as a Potent Inhibitor of Transthyretin Amyloidogenesis and its Associated Cellular Toxicity
Nat.Commun., 7, 2016
2BO9
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BU of 2bo9 by Molmil
Human carboxypeptidase A4 in complex with human latexin.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETONE, ...
Authors:Pallares, I, Bonet, R, Garcia-Castellanos, R, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Rueth, F.X.
Deposit date:2005-04-08
Release date:2005-04-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Human Carboxypeptidase A4 with its Endogenous Protein Inhibitor, Latexin.
Proc.Natl.Acad.Sci.USA, 102, 2005
1E6H
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BU of 1e6h by Molmil
A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS
Descriptor: SPECTRIN ALPHA CHAIN
Authors:Vega, M.C, Serrano, L.
Deposit date:2000-08-17
Release date:2002-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1E6G
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BU of 1e6g by Molmil
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT
Descriptor: SPECTRIN ALPHA CHAIN, SULFATE ION
Authors:Vega, M.C, Serrano, L.
Deposit date:2000-08-15
Release date:2002-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1H8K
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BU of 1h8k by Molmil
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT
Descriptor: SPECTRIN ALPHA CHAIN
Authors:Vega, M.C, Serrano, L.
Deposit date:2001-02-09
Release date:2002-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1PYT
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BU of 1pyt by Molmil
TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C
Descriptor: CALCIUM ION, CHYMOTRYPSINOGEN C, PROCARBOXYPEPTIDASE A, ...
Authors:Gomis-Ruth, F.X, Gomez, M, Bode, W, Huber, R, Aviles, F.X.
Deposit date:1995-06-21
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C.
EMBO J., 14, 1995
2K2X
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BU of 2k2x by Molmil
Solution Structure of Tick Carboxypeptidase Inhibitor at pH 3.5
Descriptor: Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D, Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2Z
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BU of 2k2z by Molmil
Solution structure of the folded domain of intermediate IIIb of Tick Carboxypeptidase Inhibitor
Descriptor: Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D, Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2Y
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BU of 2k2y by Molmil
Solution structure of the folded domain of intermediate IIIa of Tick Carboxypeptidase Inhibitor
Descriptor: Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D, Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2KMO
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BU of 2kmo by Molmil
Solution structure of native Leech-derived tryptase inhibitor, LDTI
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMR
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BU of 2kmr by Molmil
Solution structure of intermediate IIc of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMP
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BU of 2kmp by Molmil
Solution structure of intermeidate IIa of Leeck-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMQ
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BU of 2kmq by Molmil
Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
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220113

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